JUNIOR STAR Grants Help Establish Seventeen New Research Teams

Starting next January, the Czech Science Foundation (GACR) will fund seventeen new JUNIOR STAR projects. The highly selective tender is aimed at excellent early-career scientists coming to the Czech Republic from abroad or with significant international experience. With an exceptional funding amount of CZK 25 million for 5 years, the scientists will be able to build new scientific teams and focus on new areas of research.

“The JUNIOR STAR scheme is a unique opportunity for early-career scientists to gain scientific independence and enrich the Czech environment with new research topics. The interest in these grants is enormous. However, we can only afford to fund the best of the best,” said GACR President Prof. Petr Baldrian. “This is the fourth year of this grant scheme. We are delighted that it allows us to attract scientists from prestigious universities abroad to work for Czech science. These are, for example, scientists working in the U.S., the United Kingdom, Norway or Germany. We believe that the researchers have the potential to answer important questions in their field of research and build new teams that will enrich Czech science.”

Projects in all areas of basic research are eligible for funding. Scientists in the new projects will focus, for example, on accelerating drug development, optimising 3D printing of alloys, computer vision using neural networks, and the impact of bilingualism in the first year of human life.

JUNIOR STAR 2024 Projects

Registration No.ApplicantTitleOrganizationNumber of yearsDiscipline Committee
24-10275MMgr. et Mgr. Veronika Dulíková, Ph.D.Titles and bones of ancient Egyptian officials: New mathematical approach to analysing Old Kingdom dataUniverzita Karlova, Filozofická fakulta5EX7
24-10298MIng. Vít Svoboda, Dr. sc. ETH ZurichProbing Chiral Dynamics on Femtosecond TimescalesVysoká škola chemicko-technologická v Praze, Fakulta chemicko-inženýrská5EX3
24-10599MRNDr. Michal Zajaček, PhD.Stars in galactic nuclei: interrelation with massive black holesMasarykova univerzita, Přírodovědecká fakulta5EX1
24-10738MIng. Lukáš Neumann, Ph.D.Inductive Biases of Deep Neural Networks in Computer VisionČeské vysoké učení technické v Praze, Fakulta elektrotechnická5EX8
24-11058MMgr. Milan Heczko, Ph.D.Design and optimization of 3D printable oxide-dispersion-strengthened multi-principal element alloys for extreme environmentsÚstav fyziky materiálů AV ČR, v.v.i.5EX8
24-11139MNikola Paillereau, Ph. D.The effect of bilingualism on speech perception and production in the first year of lifePsychologický ústav AV ČR, v.v.i.5EX6
24-11259MRNDr. Ondřej Černý, Ph.D.Salmonella effector network inhibiting T cell immunityMikrobiologický ústav AV ČR, v.v.i.5EX4
24-11562MPaulo PaiotiCatalytic Stereoselective Synthesis of Elusive Atropisomers for Accelerating Drug DiscoveryÚstav organické chemie a biochemie AV ČR, v.v.i.5EX3
24-11622MMgr. Martin Lang, Ph.D.Computing Religious Devotion: How Reinforcing Supernatural Beliefs Affects Normative Models in the MindMasarykova univerzita, Filozofická fakulta5EX6
24-12183MKlára Marečková, Ph.D., M.Sc.Prenatal Programming of Child's Brain and Behavior: Novel Insights into the Mechanisms of the Intergenerational TransmissionMasarykova univerzita, Středoevropský technologický institut5EX4
24-11702MRNDr Martin Rejhon, PhDTunable graphene/SiC optoelectronicsUniverzita Karlova, Matematicko-fyzikální fakulta5EX2
24-11761MMgr. Lenka Gahurová, Ph.D.Transposons and ovulatory cycles – key players in long-term female fertility?Jihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta5EX5
24-11928MDr Vinicius Tadeu SantanaControl of quantum phases and entanglement by magnetic field in molecular systemsVysoké učení technické v Brně, Středoevropský technologický institut5EX2
24-12359MIng. Rafael Navrátil, Ph.D.Innovative synthetic methods enabled by transition metal catalysis and electrochemistryUniverzita Karlova, Přírodovědecká fakulta5EX3
24-12400MJan VáňaThe Sociology of Literature Revisited: Towards Epistemological Symmetry within Literature-and-Society ResearchÚstav pro českou literaturu AV ČR, v.v.i.5EX7
24-12591MSamuel Walker BraunfeldModel theory, structural combinatorics, and algorithmsUniverzita Karlova, Matematicko-fyzikální fakulta5EX1
24-12912MMaria-Cecilia ChiriacHigh-throughput host detection and cultivation of freshwater CPRs (‘Ca. Patescibacteria’)Biologické centrum AV ČR, v.v.i.5EX5

Announcement of the results of the JUNIOR STAR – 2024 (pdf)

 

JUNIOR STAR grants are evaluated exclusively by international scientists who guarantee the expertise and objectivity of the evaluation. Each project receives four reviews from members of the international discipline committees and additional ones from external reviewers, on the basis of which the evaluation panels propose the best projects for funding.

The publication of the results of the Standard Projects and POSTDOC INDIVIDUAL FELLOWSHIP tenders will take place on 30 November 2023.

Call for additional nominations for evaluation panels

Candidates interested in membership in the evaluation panels of the Czech Science Foundation may now apply throughout the year ‒ nominations are valid for two years. Replacements and reappointments occur regularly every year as the members’ terms in office expire.

The Czech Science Foundation is searching experts to join particularly the following panels as of April 2024:

Technical sciences

  • P104 – Construction Materials, Architecture and Building Science
  • P107 – Metallic Materials – Preparation and Properties

Medical and Biological Sciences

  • P303 – Cell, Developmental and Evolutionary Biology
  • P305 – Medical Physiology and Neuroscience, Diagnostics and Therapy, Translational research – specialist in neuroscience
  • P306 – Pharmacology, Toxicology, Medical Biochemistry, Medical Biophysics

Social Sciences and Humanities

  • P402 – Economic Sciences, Macroeconomics, Microeconomics, Econometrics (except Financial Econometrics), Quantitative Methods in Economics (except Operational Research) – specialist in macroeconomics and specialist in applied microeconomics (e.g. development economics, health economics, environmental economics, industrial organisation)
  • P403 – Business and Management Science, Financial Econometrics and Operational Research – specialist in operational research
  • P406 – Linguistics and Literature – linguist, ideally with a diachronic focus, and literary scientist with a focus on contemporary literature, e.g. Czech literature in an international context
  • P408 – Juridical Science and Political Science – specialist in public law with a focus on administrative law or constitutional law
  • P409 – Art Sciences – specialist in theatre history and theatre studies

Agricultural and Biological-Environmental Sciences

  • P501 – Plant Physiology and Genetics, Plant Medicine
  • P504 – Landscape Management, Forestry and Soil Biology, Ecosystem Ecology
  • P505 – Animal and Plant Ecology (added 23. 11. 2023)
  • P506 – Botany and Zoology

 

What are the main responsibilities of a panel member?

  • Being an impartial evaluator abiding by the Code of Ethics
  • Writing reviews for an average of 12-17 project proposals each year, and evaluating additional ones
  • Recommending independent external reviewers for the second phase of the evaluation
  • Monitoring the progress of the projects funded, and preparing on average 5-7 reports after project completions
  • Attending four panel meetings each year where projects are discussed

 What are the minimum requirements?

  • Academic qualifications at the level of a Ph. D. or higher
  • Active scientific activity in basic research
  • Significant contribution to the advancement of knowledge and discovery
  • Experience with basic research projects as a principal investigator or co-investigator
  • Ability to assess scientific problems in the broader context of the development of the discipline internationally

 What we offer

  • The opportunity to actively participate in the development of scientific excellence in the Czech Republic
  • Experience in evaluating and preparing grant proposals
  • Opportunity to become familiar with current trends in the field
  • Financial remuneration proportionate to the level of involvement in the evaluation process

 

For the term in office starting as of April 2024, please submit your applications and nominations by 17 December 2023.

 

 

For the 20th time: Czech Science Foundation President’s Awards Presented to Excellent Scientists

The President of the Czech Science Foundation (GACR) together with the Minister for Science, Research and Innovation awarded the five best scientific projects at the 20th anniversary ceremony of the Czech Science Foundation President’s Awards yesterday (12 October 2023) at the Martinský Palace. The award recipients from all areas of basic research have contributed to a significant expansion of knowledge in the field and will lead to further applications.

The winning projects will contribute to the comprehension of black holes, the functioning of the vertebrate brain, and the communication strategies of politicians. The other award-winning research has the potential to contribute to more effective cancer treatments and improved lubrication of human joints.

“We have awarded the best of projects over the last twenty years – ninety of them in that time. The breadth of the award-winning projects shows that Czech science is world-class in all fields of research,” said Prof. Petr Baldrian, Czech Science Foundation President. “Like the years before, this year it was extremely difficult to select the best projects, because if a project receives funding from the Czech Science Foundation, it is almost guaranteed to be high-quality research thanks to our evaluation system.”

The Czech Science Foundation President’s Award has been regularly awarded since 2003 in recognition of outstanding results achieved in grant projects completed in the previous year. Recipients are selected on the recommendation of several hundred scientists who evaluate projects funded by the Czech Science Foundation. Each winner will receive a prize of CZK 100,000. The awards are presented in five areas of basic research: Technical Sciences, Physical Sciences, Medical and Biological Sciences, Social Sciences and Humanities, and Agricultural and Biological-Environmental Sciences.

The award ceremony took place as part of the celebration of the Czech Science Foundation’s 30th Anniversary, attended by Helena Langšádlová, Minister for Science, Research and Innovation, Miloš Vystrčil, President of the Senate of the Parliament of the Czech Republic, representatives of universities, the Czech Academy of Sciences, and dozens of other distinguished guests.

Award-Winning Projects

Technical Sciences

prof. Ing. Martin Vrbka Ph.D., Brno University of Technology, Faculty of Mechanical Engineering

Investigation of Synovial Fluid Viscosupplementation and its Impact on Friction and Lubrication

Viscosupplementation is a treatment for osteoarthritis that involves injecting a hyaluronic acid-based product between the cartilages of a joint. The award-winning project investigated whether this treatment could improve the mobility of joints. The project created a joint simulator that analysed the friction and lubrication film between the articular cartilage. The project has clarified the mechanism of viscosupplementation, and provided new insights to improve the treatment of osteoarthritis.

 Physical Sciences

Roman Konoplya Ph.D., Silesian University in Opava, Institute of Physics

Testing Strong Gravity via Black Holes

The project has developed a new method for describing black holes in various theories of gravity, including those that differ from the prevailing Einstein theory. The differences between the theories are most apparent in the extremely strong gravity around black holes. This new method makes it possible to study these differences and to combine theory with experiment to help understand gravity under extreme conditions. This way, the project contributes to a full understanding of gravity and its potential applications in energy and other areas of research.

Medical and Biological Sciences

Mgr. Jakub Rohlena, Ph.D., Institute of Biotechnology, Czech Academy of Sciences

Respiration-Linked Metabolic Limitations of De Novo Pyrimidine Biosynthesis

The project investigated the metabolism of cancer cells, which influences their ability to form tumours and respond to treatment. The chain responsible for cellular respiration was found to have different functions in dividing and resting cells – the former promoting the production of organic compounds, the latter stress resistance. This difference has important implications for cancer treatment which can affect not only cancerous cells but also healthy ones. The project also discovered a new metabolic pathway that produces a key substance for cancer cell growth – aspartic acid. These findings may contribute to new innovative cancer treatments.

Social Sciences and Humanities

Mgr. Alena Kluknavská, Ph.D., Masaryk University, Faculty of Economics and Administration

Contestation of Truth: Public Discourses on Migration in Central Europe in the Post-Truth Era

The award-winning project dealt with the relativisation of truth in political communication, where facts give way to opinions. It created a theoretical framework and a tool for analysing the post-factual communication of politicians, especially in the context of polarising issues such as migration. By combining manual and automatic textual analysis, the researchers found that post-factual communication is close to both populism and disinformation. It manifests itself primarily through hostile anti-elitist accusations against opponents of creating and spreading false information and lies, and a focus on emotionality, negativity and incivility rather than facts and expertise.

Agricultural and Biological-Environmental Sciences

Mgr. Pavel Němec, Ph.D., Charles University, Faculty of Science

Evolution of Brain Complexity and Processing Capacity in Amphibians and Reptiles: A Quantitative Approach to Understanding Tetrapod Brain Evolution

The brain and its neural capacity are crucial to the evolutionary success of species. However, even species with small brains can be intelligent because of the high density of neurons in the brain. The project researchers found that birds and mammals – unlike amphibians and reptiles – have experienced brain enlargement and an increase in the number of neurons during evolution, made possible by the increased metabolism of species with constant body temperature. Furthermore, a link between the number of neurons in the hindbrain and cerebellum and the innovativeness of birds in acquiring food has been demonstrated.

SOUVISEJÍCÍ ČLÁNKY

Czech Science Foundation Celebrates 30th Anniversary

The Czech Science Foundation (GACR) today celebrates 30 years since it first funded science projects. During its existence, the Czech Science Foundation has funded over 20,000 basic research projects worth more than CZK 71 billion (nearly EUR 3 billion).

“It took less than a year to establish our Foundation, launch the first call for proposals, and start funding the first scientific projects. Even then, the management was inspired by the best practices of renowned agencies abroad, such as the National Science Foundation in the USA. The latter even recently became our partner. This allowed the Czech Science Foundation to become a world-class agency within a short period of time,” says the President of the Czech Science Foundation, Prof. Petr Baldrian.

“Thirty years of existence is our commitment for the future. The Czech Science Foundation is pursuing global priorities such as open science, supporting scientists in their early careers, balancing professional and scientific life, and implementing those priorities in the Czech scientific environment. We are constantly expanding and improving our grant opportunities to meet the needs of Czech scientists,” notes Prof Baldrian.

The thirty year anniversary of the Czech Science Foundation will be commemorated throughout the year. The history and the present of the Czech Science Foundation will be presented on the pages of the publication Czech Science Foundation: the Path of Excellence in Basic Research and in a special feature of the “Vesmír” journal, which will be published in September. You can also follow the Czech Science Foundation’s birthday wishes from prominent personalities on Facebook. The celebrations will include the presentation of the Czech Science Foundation President’s Awards in October, which will also be an anniversary event – this year they will be awarded for the 20th time.

The Czech Science Foundation is the only provider of grants earmarked for basic research projects in all fields of science in the Czech Republic. In 2023, it has a budget of CZK 4.7 billion (approx. EUR 195 million). Over 11,000 expert reviews are produced each year to evaluate projects. In addition to the main calls for proposals, funding is also provided for narrowly focused calls for scientists in their early careers, but also for seasoned researchers, and for international research projects.

SOUVISEJÍCÍ ČLÁNKY

Tenders for 2024 Projects

The Czech Science Foundation (GACR) is announcing calls for proposals for tenders in the area of Standard Projects, JUNIOR STAR, POSTDOC INDIVIDUAL FELLOWSHIP, and International and Lead Agency projects. The submission deadline is 4 April. The winners will be announced in November this year. Projects which win funding after passing the multi-stage evaluation process will be launched in 2024.

“The aim of the Czech Science Foundation is not only to promote basic research, but mainly to increase its efficiency. The fact that scientists compete with each other for support is motivating – they have to submit an excellent project to receive funding. Even the preparation of the Project Proposals results in a thorough reflection on the scientific topics they can further address,” said the President of the Czech Science Foundation, Prof. Petr Baldrian. “The evaluation of the projects is carried out by experts on the given topics – over 400 of them work for GA CR from various fields and institutions. Thousands of foreign scientists then evaluate the projects that make it to the second round of selection.”

One of the upgrades in the new tender terms intended to facilitate the work-life and work-family balance is the option to pause the project for 6 to 18 calendar months, or to extend the project for up to 18 months. “This is yet another measure to help our investigators during difficult times – not necessarily maternity or parental leave, but also long-term illness or caring for a loved one,” added the President of GACR.

For this year, several rules have also been modified to allow for greater flexibility in the use of funds allocated – transfers of funds between items of the basic structure up to CZK 100,000 will be possible without submitting an request.

The submission deadline for Proposals for projects starting in 2024 is 4 April 2023. The winning proposals will be announced in November this year, except for international tenders, which will be announced in coordination with the partner agency abroad. GACR has brought on board a new partner agency, the HRZZ of Croatia, and joint international projects involving HRZZ may now be submitted. The new EXPRO tender will not be launched until next year.

Standard projects

Standard projects are the backbone of targeted aid for basic research in the Czech Republic, with GACR having financed hundreds of them each year since its founding in 1993. Through these projects, the best basic research in all areas is supported. Standard projects are usually worked on for three years and their proposals may be submitted by all researchers and their teams without limits on the length of their scientific careers. Project proposals are evaluated on the basis of a multi-level selection process.

JUNIOR STAR

The JUNIOR STAR tender is almost always met with great interest by applicants from the ranks of excellent scientists in basic research who are at the beginning of their career (up to 8 years after being awarded their Ph.D. titles) who have had their work published in prestigious international journals and have significant foreign experience. The goal of these five-year projects with a budget of up to 25 million CZK is to give the applicants a chance to gain scientific independence, including potentially founding their own research group to bring new topics into Czech science. Similarly to EXPRO projects, the review of JUNIOR STAR project proposals is carried out solely by external reviewers.

POSTDOC INDIVIDUAL FELLOWSHIP

For the third time, GACR is announcing the POSTDOC INDIVIDUAL FELLOWSHIP (PIF) tender this year. This type of grant is aimed at scientists who have finished their doctoral studies in the past four years. It can take two forms – either allowing a Czech scientist to carry out two years of research at a prestigious research centre abroad (with the condition of spending a third year at a research centre in the Czech Republic) or allowing a Czech postdoc or foreign scientist to come carry out research and begin their career at a Czech research centre.

International projects

Projects worked on by scientists and their teams in cooperation with researchers from partner states are a separate category of grants. Project proposals are either evaluated by both agencies (bilateral cooperation), or they are recommended for funding by one agency and the other adopts its recommendations (Lead Agency cooperation).

Bilateral-cooperation

Lead Agency

For reasons on the side of the Croatian Science Foundation (HRZZ), a decision on the launch of this year’s call, in which GA CR would be the evaluating agency, will be made in the coming weeks.

Further international calls based on Lead Agency cooperation may be launched during the year.

SOUVISEJÍCÍ ČLÁNKY

Czech Science Foundation to Fund over 500 New Projects Starting this January

In its largest grant scheme, the Czech Science Foundation (GACR) will fund 459 new projects in all areas of research starting next year. These projects will receive CZK 3.5 billion over the next three years. In addition to Standard Projects, the results of the POSTDOC INDIVIDUAL FELLOWSHIP tender for early-career scientists have been announced. Together with the EXPRO and JUNIOR STAR projects, which were announced a month ago, GACR will fund over 500 scientific projects worth a total of CZK 4.5 billion starting next year.

“I would like to warmly congratulate all the applicants who succeeded in our Standard Projects tender, and wish them all to achieve their goals and deliver impressive results with the support of the funding from the Czech Science Foundation. It is extremely difficult to succeed in our tenders, which we have been running every year for almost 3 decades – this year only about one-fifth of the best proposals succeeded,” said Petr Baldrian, President of GACR. ” Also thanks to a properly designed selection process – where all successful projects have to receive the backing of both Czech evaluators and independent specialists from abroad – we can be sure that we are selecting the best projects and that the funds earmarked for basic research are used effectively.”

Standard Projects

Standard Projects are the core of targeted aid for basic research in the Czech Republic. Starting in 2023, GACR will be funding 459 new Standard Projects worth CZK 3.5 billion. All researchers and their teams, regardless of their age and experience, may submit proposals for projects with a duration of up to three years. This project type has been funded since 1993.

Projects Funded  2023 onwards

Registration No.ApplicantTitleOrganizationNumber of yearsDiscipline committee
23-04712Sprof. Ing. Zdeněk Kala, Ph.D.Importance of Stochastic Interactions in Computational Models of Structural MechanicsVysoké učení technické v Brně, Fakulta stavební31. Technical Sciences
23-04724SFrantišek ŠebekComputational modelling of ductile fracture of identical wrought and printed metallic materials under ultra-low-cycle fatigueVysoké učení technické v Brně, Fakulta strojního inženýrství31. Technical Sciences
23-04744Sprof. Ing. Zbyšek Pavlík, Ph.D.Research of heavy metals immobilization in alternative low-carbon compositesČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-04772Sprof. Ing. Robert Černý, DrSc.Physical and chemical processes in alkali activated ceramics exposed to high temperaturesČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-04806SMgr. Ing. Oleg Heczko, Dr.Hyperfine field - new probe for Heusler alloysFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-04824SIng. Lenka Mészárosová, Ph.D.Influence of alternative raw material components on improvement of physico-mechanical properties of aerated autoclaved concreteVysoké učení technické v Brně, Fakulta stavební31. Technical Sciences
23-04928SIng. Petr Čermák, Ph.D.Mycelium-Lignocellulose-Based Bio-Composites: From Growth Kinetics to Physico-Mechanical Properties (MyBiCo)Mendelova univerzita v Brně, Lesnická a dřevařská fakulta31. Technical Sciences
23-04951Sdoc. RNDr. Pavel Rovnaník, Ph.D.Modification of rheological properties of alkali-activated materials with new types of organic admixturesVysoké učení technické v Brně, Fakulta stavební31. Technical Sciences
23-04971Sprof. Ing. Jaroslav Kruis, Ph.D.Prediction of mechanical behaviour of structures 3D printed based on alloy of titanium with betastructureČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-04974Sprof. Ing. Miroslav Vořechovský, Ph.D.Coupled chemo-mechanical model of normal and cancer microenvironmentVysoké učení technické v Brně, Fakulta stavební31. Technical Sciences
23-05002Sprom. fyz. Jiří Vacík, CSc., Ph.D.Black metals surface-decorated by MXenes as sensitive chemiresistor layersÚstav jaderné fyziky AV ČR, v.v.i.31. Technical Sciences
23-05082SRNDr. Theodor Staněk, Ph.D.The research on the combined effect of sulfur, copper and lithium oxides on the formation and properties of Portland cement clinker.Výzkumný ústav stavebních hmot, a.s.31. Technical Sciences
23-05104Sprof. RNDr. Roman Barták, Ph.D.Multi-Robotic Path Planning and ExecutionUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-05122SMgr. Martin Boháč, Ph.D.The role of combination of fluxes, mineralizers and SCMs on properties of low-energy clinkerVýzkumný ústav stavebních hmot, a.s.31. Technical Sciences
23-05126Sdoc. Ing. Pavel Novák, Ph.D.Sintered silicides as the future tool materials Vysoká škola chemicko-technologická v Praze, Fakulta chemické technologie31. Technical Sciences
23-05128SIng. Kamil Souček, Ph.D.Influence of textural and structural features on failure of transversely isotropic rocks examined using 4D X-ray computed tomographyÚstav geoniky AV ČR, v.v.i.31. Technical Sciences
23-05139Sprof. Ing. Pavel Lejček, DrSc.Structure and properties of metastable metal-matrix composites produced by 'bottom-up' processing of core-shell powdersFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-05154Sprof. RNDr. David Lukáš, CSc.Investigation of prokaryotic and eukaryotic cell interactions with nanofibers differing in morphology and structureTechnická univerzita v Liberci, Fakulta přírodovědně-humanitní a pedagogická31. Technical Sciences
23-05235SIng. Michal Zeleňák, Ph.D.Study of mechanism of formation stable high-frequency oscillations generated in a liquid under high pressuresÚstav geoniky AV ČR, v.v.i.31. Technical Sciences
23-05266Sprof. Dr. Ing. Josef KrýsaStudy of key factors influencing the efficiency of photoelectrochemical cells using sunlight for synthesis reactions and water purificationVysoká škola chemicko-technologická v Praze, Fakulta chemické technologie31. Technical Sciences
23-05338SProf. Yannis Dafalias, Ph.D.Mechanical and structural properties of additively manufactured AlSi10Mg alloy with effect of powder recyclingÚstav termomechaniky AV ČR, v.v.i.31. Technical Sciences
23-05372Sprof. Ing. Sergej Hloch, Ph.D.Surface and subsurface erosion due to multiple droplet impingementÚstav geoniky AV ČR, v.v.i.31. Technical Sciences
23-05435Sprof. Ing. Jiří Němeček, Ph.D.Nanomechanical performance of cementitious composites under radiation impact and variable environmental actionsČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-05500SM.Sc. Oleg Babčenko, Ph.D.Effect of surface treatments on the performance of silicon-based secondary materials in cementitious compositesFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-05507SIng. Jan Mrázek, Ph.D.Advanced inorganic nanocomposites for distributed sensors of harmful radiationÚstav fotoniky a elektroniky AV ČR, v.v.i.31. Technical Sciences
23-05575SRNDr. Lukáš Chrpa, Ph.D.Urban Traffic Control by Means of Automated PlanningČeské vysoké učení technické v Praze, Fakulta elektrotechnická31. Technical Sciences
23-05592SIng. Jaroslav Čapek, Ph.D.Influence of surface modifications on the functionality of zinc-based absorbable materials for applications in bone reconstructionsFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-05615SRNDr. Eva Mihóková, CSc.Scintillating multimodal materials and quantum heterostructures.Fyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-05646Sdoc. Ing. Zdeněk Bečvář, Ph.D.Intelligent Radio Resource and Mobility Management based on Federated LearningČeské vysoké učení technické v Praze, Fakulta elektrotechnická31. Technical Sciences
23-05662SRNDr. Petr Harcuba, Ph.D.Investigation of deformation mechanisms in metallic materials by advanced micromechanical testingUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-05701Sdoc. Ing. Pavel Peterka, Ph.D.Overcoming temperature limitations of kW-class thulium fiber lasersÚstav fotoniky a elektroniky AV ČR, v.v.i.31. Technical Sciences
23-05736SRNDr. Michal Pavelka, Ph.D.Geometric multiscale thermodynamics of complex fluidsUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-05818SRNDr. Jan Demel, Ph.D.Activated Borane as Lewis Acid Based CatalystÚstav anorganické chemie AV ČR, v.v.i.31. Technical Sciences
23-05845SIng. Helena Škutková, Ph.D.Real-time determination of infection threats from raw nanopore signals using machine learning techniquesVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií31. Technical Sciences
23-05878SIng. Jan Vlček, Ph.D.Thin films of transition metal complexes with vacant positions in the ligand field for gas sensing applicationFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-05895SIng. Jiří Červenka, Ph.D.Development of advanced electrode-electrolyte interfaces for next-generation high-voltage aqueous batteriesFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-05915SIng. Ján Lančok, Ph.D.Electric charge transport in heterostructures of semiconductor oxides with copper halidesFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-05918SIng. Dana Koňáková, Ph.D.Smart and programmable housing and living – energy storage systems are hidden everywhere in our buildings within basic construction componentsČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-05947Sdoc. Mgr. Pavel Souček, Ph.D.Ab-initio guided investigation of refractory metal-based high entropy ceramic coatingsMasarykova univerzita, Přírodovědecká fakulta31. Technical Sciences
23-06016Sdoc. Ing. Martina Eliášová, CSc.Surface treatment of glass and its influence on the reliability of adhesive bonding for glass structures at elevated temperaturesČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-06070Sdoc. Ing. Jan Jeřábek, Ph.D.Fundamental research on designing of CMOS fractional-order elementsVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií31. Technical Sciences
23-06152SIng. Michal Kohout, Ph.D.Modular approach towards chiral membranes for scalable enantioseparation of racemic drugsVysoká škola chemicko-technologická v Praze, Fakulta chemické technologie31. Technical Sciences
23-06157SIng. Lenka Scheinherrová, Ph.D.Impact of C3A on the early strength of cementČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-06159SIng. Jakub Šístek, Ph.D.Vortical structures: advanced identification and efficient numerical simulationMatematický ústav AV ČR, v.v.i.31. Technical Sciences
23-06167SIng. Ivo Kuběna, Ph.D.High-temperature damage mechanisms in Ni-based superalloy fabricated by laser powder bed fusionÚstav fyziky materiálů AV ČR, v.v.i.31. Technical Sciences
23-06169SIng. Tomáš Prošek, Ph.D.The role of precipitates in hydrogen transport and hydrogen embrittlement of Al alloysVysoká škola chemicko-technologická v Praze, Účelová celoškolská výzkumná a vzdělávací pracoviště31. Technical Sciences
23-06220Sprof. Dr. Ing. Eduard Rohan, DSc.Flexoelectric periodic structures for fluid transport and energy harvestingZápadočeská univerzita v Plzni, Fakulta aplikovaných věd31. Technical Sciences
23-06263SMgr. Petr Klapetek, Ph.D.Thermophysical characterisation of thin filmsČeský metrologický institut31. Technical Sciences
23-06285SMgr. Jakub Holovský, Ph.D.Novel ionic crystals and their surfaces as the key to future photovoltaic materials (NicePV)České vysoké učení technické v Praze, Fakulta elektrotechnická31. Technical Sciences
23-06352Sprof. Ing. Petr Konvalinka, CSc.Directed electromagnetic orientation of dispersed fibre reinforcement for optimal stress resistance in concrete structural membersČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-06476Sprof. RNDr. Josef Diblík, DrSc.Analysis of Discrete and Continuous Dynamical Systems with Emphasis on Identification ProblemsVysoké učení technické v Brně, Středoevropský technologický institut31. Technical Sciences
23-06506Sprof. Ing. Tomáš Vojnar, Ph.D.Advanced Analysis and Verification for Advanced SoftwareVysoké učení technické v Brně, Fakulta informačních technologií31. Technical Sciences
23-06543SRNDr. Milan Dopita, Ph.D.Structural changes induced by light soaking in mixed-halide perovskitesUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-06548Sprof. Ing. Roman Jambor, Ph.D.Superhydrophobic materials based on heteroboroxinesUniverzita Pardubice, Fakulta chemicko-technologická31. Technical Sciences
23-06562SMgr. Jan Hynek, Ph.D.Optimization of proton conductivity in Zr-based metal-organic frameworks by peripheral substitution of porphyrin ligandsÚstav anorganické chemie AV ČR, v.v.i.31. Technical Sciences
23-06644Sprof. RNDr. Jan Valenta, Ph.D.Fluorescent radiative-cooling materials: development, testing and applicationsUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-06691SRNDr. Jakub Zázvorka, Ph.D.Development of a sensing device using magneto-optical diffraction on ordered magnetic texturesUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-06746SMgr. Dana Kubies, CSc.Polyelectrolyte multilayer films based on charge-shifting synthetic polycations and heparin for delivery of growth factorsÚstav makromolekulární chemie AV ČR, v.v.i.31. Technical Sciences
23-06793SDr. Hanna SophaEngineering of bipolar electrochemical technology for the next generation of TiO2 nanotube layersUniverzita Pardubice, Fakulta chemicko-technologická31. Technical Sciences
23-06843Sdoc. Dr. Ing. Petr KlusoňAdvanced thin film photocatalysts on a basis of graphitic carbon nitrideÚstav chemických procesů AV ČR, v.v.i.31. Technical Sciences
23-06856SIng. Václav Pouchlý, Ph.D. Ing. Paed. IGIPCompositionally complex ceramic oxides: Ab initio design and experimental verificationVysoké učení technické v Brně, Fakulta strojního inženýrství31. Technical Sciences
23-06912SRNDr. David Mareček, Ph.D.Identification and Prevention of Unwanted Gender Bias in Neural Language ModelsUniverzita Karlova, Matematicko-fyzikální fakulta21. Technical Sciences
23-06920Sprof. Ing. Zbyněk Šika, Ph.D.Functionally biomimetic exoskeleton of human upper limb for selective muscle augmentationČeské vysoké učení technické v Praze, Fakulta strojní31. Technical Sciences
23-06925SMgr. Daniil Nikitin, Ph.D.Resistive switching in metal nanofluids: a novel approach in neuromorphic engineeringUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-06957SIng. Michal Mikl, Ph.D.New strategies in processing of multi-echo fMRI dataMasarykova univerzita, Středoevropský technologický institut31. Technical Sciences
23-07013SIng. Richard Pokorný, Ph.D.Characterization of gas evolution and transient melt formation to elucidate and minimize primary foaming during glass meltingVysoká škola chemicko-technologická v Praze, Fakulta chemické technologie31. Technical Sciences
23-07071SDr. Raul ZazpeTwo-dimensional transition metal-based phosphides by Atomic Layer DepositionUniverzita Pardubice, Fakulta chemicko-technologická31. Technical Sciences
23-07228SIng. Michal Novotný, Ph.D.Novel thermoelectric, thermovoltaic, and phonoelectric heat conversion systems based on nitrides semiconductorsFyzikální ústav AV ČR, v.v.i.31. Technical Sciences
23-07235SIng. Miroslav Šmíd, Ph.D.Microstructural manipulation of austenitic steels by laser powder bed fusion techniqueÚstav fyziky materiálů AV ČR, v.v.i.31. Technical Sciences
23-07244Sdoc. Ing. Michal Sedlačík, Ph.D.Anisotropic Magnetorheological Elastomers with Controlled Electrical PropertiesUniverzita Tomáše Bati ve Zlíně, Univerzitní institut31. Technical Sciences
23-07280Sdoc. Ing. Michal Hajžman, Ph.D.Identification and compensation of imperfections and friction effects in joints of mechatronic systemsZápadočeská univerzita v Plzni, Fakulta aplikovaných věd31. Technical Sciences
23-07292SRNDr. Viliam Kolivoška, Ph.D., MBAAdditive or subtractive manufacturing: Which is more powerful to achieve stable electroreduction of carbon dioxide at high reaction rates?Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.31. Technical Sciences
23-07294Sprof. Mgr. Pavel Rajmic, Ph.D.From perceptron to perception: psychoacoustically motivated audio reconstruction using learned componentsVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií31. Technical Sciences
23-07299SIng. Ondřej Kuželka, Ph.D.Statistical Relational Learning in Dynamic DomainsČeské vysoké učení technické v Praze, Fakulta elektrotechnická31. Technical Sciences
23-07356SIng. Ondřej Kašpar, Ph.D.Development of inhalable carriers for in-situ production of natural antibioticsVysoká škola chemicko-technologická v Praze, Fakulta chemicko-inženýrská31. Technical Sciences
23-07361SIng. Lukáš Münster, Ph.D.Synthesis of gold nanoparticles for SERS and catalysis guided by selectively oxidized polysaccharidesUniverzita Tomáše Bati ve Zlíně, Univerzitní institut31. Technical Sciences
23-07384SIng. Robert Macků, Ph.D.Back-gated few-layers graphene gas sensors: charge transport and its fluctuation used for performance improvementVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií31. Technical Sciences
23-07415SIng. Libor Sitek, Ph.D.Study of rock erosion resistance using accelerated hydro-abrasive and cavitation simulationÚstav geoniky AV ČR, v.v.i.31. Technical Sciences
23-07425Sprof. Ing. Petr Humpolíček, Ph.D.Anisotropic and Electro-Conducting BiomaterialsUniverzita Tomáše Bati ve Zlíně, Univerzitní institut31. Technical Sciences
23-07445SMgr. Elena Miliutina, Ph.D.Preparation, characterization, and utilization of hybrid MOF-Me nanostructured materialsVysoká škola chemicko-technologická v Praze, Fakulta chemické technologie31. Technical Sciences
23-07517SDr. rer. nat. Martin SaskaAgile swarms of aerial robots with reliable multimodal sensing and state-estimation capabilitiesČeské vysoké učení technické v Praze, Fakulta elektrotechnická31. Technical Sciences
23-07518Sdoc. Ing. Milan Polívka, Ph.D.Advanced structures and characterization methods of nonlinear backscattering for identification and sensingČeské vysoké učení technické v Praze, Fakulta elektrotechnická31. Technical Sciences
23-07574SIng. Miloš Krbal, Ph.D.Tunnig of optical properties of amorphous, thermally and laser-crystallized chalcogenide-based phase change materials for nanophotonic applicationsUniverzita Pardubice, Fakulta chemicko-technologická31. Technical Sciences
23-07617Sprof. RNDr. Tomáš Šikola, CSc.2D single crystals of MXenesVysoké učení technické v Brně, Středoevropský technologický institut31. Technical Sciences
23-07722SIng. Milan Maly, Ph.D.Advanced energy-efficient modifications of twin-fluid atomizerVysoké učení technické v Brně, Fakulta strojního inženýrství31. Technical Sciences
23-07772Sprof. Dr. Ing. Václav MatoušekStructure and dynamics of multi-species bed load transport above erodible plane bed in open channelČeské vysoké učení technické v Praze, Fakulta stavební31. Technical Sciences
23-07781Sdoc. RNDr. Irena Holubová, Ph.D.Self-Adapting Management of Multi-Model DatabasesUniverzita Karlova, Matematicko-fyzikální fakulta31. Technical Sciences
23-07785Sprof. Ing. Tomáš Polcar, Ph.D.Superlubricity: sliding of 2D materialsČeské vysoké učení technické v Praze, Fakulta elektrotechnická31. Technical Sciences
23-07848SDr. Alexander MozalevNovel self-organized nanorod arrays of molybdenum anodic oxides, compounds and heterostructures as emerging multipurpose electronic nanomaterialsVysoké učení technické v Brně, Středoevropský technologický institut31. Technical Sciences
23-07879SIng. Karel Slámečka, Ph.D.Exploring how nitriding affects fatigue behaviour of additive manufactured titanium hierarchical porous structuresVysoké učení technické v Brně, Středoevropský technologický institut31. Technical Sciences
23-07953SIng. Andrea Konečná, Ph.D.Shaped beams for a new era of electron microscopy and spectroscopyVysoké učení technické v Brně, Fakulta strojního inženýrství31. Technical Sciences
23-07962SIng. Vladislav Krzyžánek, Ph.D.Advanced cryo-optofluidic platform for correlative light and electron microscopy (CLEM)Ústav přístrojové techniky AV ČR, v.v.i.31. Technical Sciences
23-07971SIng. Štěpán Kment, Ph.D.Lead-Free Double Perovskite Nanocrystals for Photocatalytic CO2 ReductionUniverzita Palackého v Olomouci, Český institut výzkumu a pokročilých technologií31. Technical Sciences
23-08001SIng. Pavel Procházka, Ph.D.Tunable Charge Injection Layers for Efficient Charge Transfer Through Metal Electrode-Organic Semiconductor InterfaceVysoké učení technické v Brně, Středoevropský technologický institut31. Technical Sciences
23-08020SRNDr. Petra Veselá, Ph.D.Tomography of thin-film interfaces by using random-pulse picosecond sonarÚstav fyziky plazmatu AV ČR, v. v. i.31. Technical Sciences
23-08038SIng. Petr Tej, Ph.D.Optimized arrangement of reinforcement in cementisous compositesČeské vysoké učení technické v Praze, Kloknerův ústav31. Technical Sciences
23-04659SIng. Petr Beier, Ph.D.Utilization of organic fluorinated azides for the synthesis of unusual nitrogen heterocyclesÚstav organické chemie a biochemie AV ČR, v.v.i.32. Physical Sciences
23-04679Sprof. Ing. Daniel Klír, Ph.D.The study of z-pinch physics with novel diagnostic methods using fast ionsČeské vysoké učení technické v Praze, Fakulta elektrotechnická32. Physical Sciences
23-04683SChristopher Lambie-Hanson, Ph.D.Compactness in set theory, with applications to algebra and graph theoryMatematický ústav AV ČR, v.v.i.32. Physical Sciences
23-04703Sdoc. RNDr. Michal Roth, CSc.Alternative route to capillary monolithic silica columns from discrete particles treated with supercritical waterÚstav analytické chemie AV ČR, v.v.i.32. Physical Sciences
23-04720Sprof. RNDr. Luboš Pick, CSc., DSc.Fine properties of functions, operators and function spacesUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-04734SAlessandro FabbrizioExperimental determination of Be diffusivity in pyroxenes and plagioclase: a new tool for geospeedometryUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-04746Sdoc. RNDr. Ilja Turek, DrSc.Theory of magnetic systems in electric and electromagnetic fieldsÚstav fyziky materiálů AV ČR, v.v.i.32. Physical Sciences
23-04766SDoc. RNDr. Martin Kružík, Ph.D., DSc.Variational approaches to dynamical problems in continuum mechanicsÚstav teorie informace a automatizace AV ČR, v.v.i.32. Physical Sciences
23-04776Sprof. RNDr. Ondřej Kalenda, Ph.D., DSc.Interplay of algebraic, metric, geometric and topological structures on Banach spacesUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-04825SNeil ThapenLogic and unsatisfiabilityMatematický ústav AV ČR, v.v.i.32. Physical Sciences
23-04946SMgr. Josef Ďurech, Ph.D.Study of evolutionary paths of asteroids driven by non-gravitational forces with photometric observationsUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-05051Sprof. RNDr. Martin Mihaljevič, CSc.Metals and their isotopes in active and abandoned mining areas of sub-Saharan Africa – towards understanding of their geochemistry and impactsUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-05083SRNDr. Jindřich Fanfrlík, Ph.D.Modeling Biologically Active Heteroborane ClustersÚstav organické chemie a biochemie AV ČR, v.v.i.32. Physical Sciences
23-05111Sprof. RNDr. Petr Klán, Ph.D.Synthesis and Photophysical and (Photo)chemical Properties of Novel Cyanine DerivativesMasarykova univerzita, Přírodovědecká fakulta32. Physical Sciences
23-05146SMgr. Jindřich Karban, Ph.D.Study of galectin-glycan interactions using fluoroglycomimeticsÚstav chemických procesů AV ČR, v.v.i.32. Physical Sciences
23-05148Sdoc. RNDr. Jan Šťovíček, Ph.D.Homological and structural theory in geometric contextsUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-05207Sprof. RNDr. Josef Málek, CSc., DSc.Development of reliable computational tools adequate for the study of fluid-structure interactions, with special relevance to cardiovascular problemsUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-05217Sprof. RNDr. Katarína Holcová, Ph.D.Seagrass/seaweed meadows – overlooked Phanerozoic ecosystems: their contribution to shelf biodiversity and identification in the fossil recordUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-05241Sdoc. Mgr. Ctirad Hofr, Ph.D.Transcriptional regulation of Epstein–Barr oncovirus – biophysical implications for Rta-targeted therapyMasarykova univerzita, Přírodovědecká fakulta32. Physical Sciences
23-05242Sprof. RNDr. Roman Šimon Hilscher, DSc.Oscillation theory on hybrid time domains with applications in spectral theory and matrix analysisMasarykova univerzita, Přírodovědecká fakulta32. Physical Sciences
23-05271Sprof. Ing. Vladimír Šindelář, Ph.D.Chemical modification of bambusurils for adjusting their binding affinity and selectivityMasarykova univerzita, Přírodovědecká fakulta32. Physical Sciences
23-05293SIng. Jan Rohlíček, Ph.D.Pushing the limits of complexity in solving crystal structures using a combination of XRPD and ssNMRFyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05378SDr. Tao WuSynthesis and Characterization of Lanthanide-Luminescence Probes for Biomolecular Raman Spectroscopy and ImagingÚstav organické chemie a biochemie AV ČR, v.v.i.32. Physical Sciences
23-05439Sprof. RNDr. Juraj Glosík, DrSc.State specific recombination of astrophysically important ions with electronsUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-05443SIng. Ctirad Červinka, Ph. D.Computer-aided design of metal-organic porous liquids for gas adsorption and catalysis Vysoká škola chemicko-technologická v Praze, Fakulta chemicko-inženýrská32. Physical Sciences
23-05486Sdoc. Ing. Pavel Jelínek, Ph.D.On-surface synthesis and characterization of polyradical moleculesUniverzita Palackého v Olomouci, Přírodovědecká fakulta32. Physical Sciences
23-05557SRNDr. Michal Kolář, Ph.D.Towards atomistic understanding of the first moments in the life of proteinVysoká škola chemicko-technologická v Praze, Fakulta chemicko-inženýrská32. Physical Sciences
23-05577SDr. Catherine AnnenGeneration, extent, and longevity of magma mush columnsGeofyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05578SValentyn Laguta, DrSc.Electric-field control of spin-qubits in quantum paraelectricsFyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05586Sdoc. RNDr. Dalibor Šatínský, Ph.D.Nanofibers as advanced extraction materials for chromatographic analysisUniverzita Karlova, Farmaceutická fakulta v Hradci Králové32. Physical Sciences
23-05639Sprof. RNDr. Jiří Šponer, DrSc.Molecular dynamics simulations of RNA: from static structures to molecular ensemblesBiofyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05640Sdoc. RNDr. Tomáš Ostatnický, Ph.D.Electron tunneling in coupled semiconductor nanostructures triggered by plasmon resonance at terahertz frequenciesUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-05651Sdoc. RNDr. Barbora Kozlíková, Ph.D.ChromeXplore: Interactive visual exploration of chromatinMasarykova univerzita, Fakulta informatiky32. Physical Sciences
23-05688Sdoc. RNDr. Karolina Schwarzová, Ph.D.Electrochemical sensors based on nanostructured and functionalized sp2 and sp3 carbon surfaces for (bio)analytical applicationsUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-05737Sdoc. RNDr. Daniel Hlubinka, Ph.D.Functional Fourier Data AnalysisUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-05784SRNDr. Pavel Galář, Ph.D.Nanocrystal Photoluminescence Intermittency: Elucidation of long-term charge carrier dynamics through ultrafast processesFyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05798SMgr. Hana Engstová, Ph.D.Fluorescence nanoscopy of pancreatic beta cellsFyziologický ústav AV ČR, v.v.i.32. Physical Sciences
23-05827SIng. Jakub Vícha, Ph.D.Extension of Scientific Potential of Gamma-ray Observatory SWGO by Cherenkov TelescopesFyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05837SRNDr. Kateřina Kůsová, Ph.D.Phonon recycling in semiconductor quantum dotsFyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05891SHéctor Vázquez, Ph.D.Design of molecular circuits from simulations and machine learning Fyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-05914Sprof. RNDr. Jiří Podolský, CSc., DSc.Advanced Techniques Applied to Black-Hole and Gravitational-Wave Exact SpacetimesUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-05940SProf. Mgr. Lubomír Rulíšek, CSc. DSc.Catalytic Metallopeptides: Bridging the Gap Between Small Molecule Catalysts and MetalloenzymesÚstav organické chemie a biochemie AV ČR, v.v.i.32. Physical Sciences
23-05972SRNDr. Pavel Kubáň, Ph.D. DSc.Advanced techniques for fully autonomous dried blood spot analysesÚstav analytické chemie AV ČR, v.v.i.32. Physical Sciences
23-05983SRNDr. Jitka Myšková, Ph.D.Directionality of non-linear optical properties of fluorescent proteinsUniverzita Karlova, 1. lékařská fakulta32. Physical Sciences
23-06115SRNDr. Aleš Daňhel, Ph.D.Development of Electroanalytical Methods for Interaction of Galectins and Glycomimetic Ligands – New Potential Anticancer DrugsBiofyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-06177Sprof. PharmDr. Petr Zimčík, Ph.D.J-dimers of PhthalocyaninesUniverzita Karlova, Farmaceutická fakulta v Hradci Králové32. Physical Sciences
23-06198Sprof. RNDr. Jiří Frýda, Dr.Response of mid-Paleozoic faunal communities to significant environmental changes: a study of the Mulde, Lau, Choteč events from the Prague BasinČeská zemědělská univerzita v Praze, Fakulta životního prostředí32. Physical Sciences
23-06224Sprof. RNDr. Pavel Zemánek, Ph.D.Semiclassical Nonlinear Electro-Optical LevitationÚstav přístrojové techniky AV ČR, v.v.i.32. Physical Sciences
23-06308Sprof. Mgr. Radim Filip, Ph.D.Single-phonon quantum acousticsUniverzita Palackého v Olomouci, Přírodovědecká fakulta32. Physical Sciences
23-06345Sprof. RNDr. Jiří Zahradník, DrSc.Seismo-geodynamic modeling of the Hellenic subductionUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-06364Sdoc. Mgr. Jiří Pittner, Dr. rer. nat., DSc.Excited state molecular dynamics with non-adiabatic and spin-orbit effects assisted by machine learningÚstav fyzikální chemie J. Heyrovského AV ČR, v.v.i.32. Physical Sciences
23-06369SDR Artur SlobodeniukRole of decoherence in high-order nonlinear optical interactionsUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-06370SMgr. Petr Kolínský, Ph.D.Recognition of remote velocity anomalies in the upper mantleGeofyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-06401Sprof. RNDr. Jana Šafránková, DrSc.Where and how the solar wind is accelerated and heated and how these processes affect its evolution?Univerzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-06430SIng. Ivana Kolmašová, Ph.D.Power of nature: extreme lightning flashesÚstav fyziky atmosféry AV ČR, v. v. i.32. Physical Sciences
23-06437SMgr. Štěpán Timr, Ph.D.Allostery and spatial organization in glycolysis: the role of phosphofructokinase 1Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.32. Physical Sciences
23-06439Sdoc. Mgr. Milan Krtička, Ph.D.Collective dynamics of nuclear electromagnetic excitationsUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-06451SGregory RuetenikInterplay between relative sea-level and surface processes: comparing responses across tectonically active and inactive terrainsGeofyzikální ústav AV ČR, v.v.i.32. Physical Sciences
23-06465Sprof. Ing. Radek Cibulka, Ph.D.Merging photochemistry and electrochemistry in flavin-based redox catalysisVysoká škola chemicko-technologická v Praze, Fakulta chemické technologie32. Physical Sciences
23-06498SLinus WulffDualities and higher derivativesMasarykova univerzita, Přírodovědecká fakulta32. Physical Sciences
23-06530SRNDr. Stanislav Musil, Ph.D.Unique methods of ultratrace analysis of selected technology-critical elementsÚstav analytické chemie AV ČR, v.v.i.32. Physical Sciences
23-06600SRNDr. Petr Šimek, CSc.New approaches in targeted metabolomic analysis of unstable metabolites with oxo group: labeling with quaternary ammonium and stable isotopesBiologické centrum AV ČR, v.v.i.32. Physical Sciences
23-06708Sprof. RNDr. Jiří Žák, Ph.D.Detrital zircon geochronology as a tool for interpreting terrane provenanceUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-06718Sprof. RNDr. Petr Štěpnička, Ph.D., DSc., FRSCRigid and functional ferrocene phosphinesUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-06755SRNDr. Martin Lepšík, Ph.D.Atomistic Understanding of Peptide Hormone Binding to Their Receptors and Mimetics Design via Advanced Computations and Experimental VerificationÚstav organické chemie a biochemie AV ČR, v.v.i.32. Physical Sciences
23-06770SMgr. Michal Kovaľ, Ph.D.Precision Tests of the Standard Model at the NA62 experimentUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-06866SRNDr. Karel Škoch, Ph.D.Borenium cations (hetero)boraalkenes as sensors, small molecule activators and catalystsÚstav anorganické chemie AV ČR, v.v.i.32. Physical Sciences
23-06909Sprof. RNDr. Ing. Jaroslav Burda, DrSc.Grand-canonical description of the chemical reactions at constant pH.Univerzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-07031SDoc. Ing. Michal Šprlák, PhD.Ellipsoidal modelling of planetary gravitational fieldsZápadočeská univerzita v Plzni, Fakulta aplikovaných věd32. Physical Sciences
23-07043SRNDr. Martin Kološ, Ph.D.Black Hole MagnetosphereSlezská univerzita v Opavě, Fyzikální ústav v Opavě32. Physical Sciences
23-07066Sprof. RNDr. Petr Slavíček, Ph.D.Time-dependent simulations for time-resolved electronic spectroscopiesVysoká škola chemicko-technologická v Praze, Fakulta chemicko-inženýrská32. Physical Sciences
23-07110SMgr. Jiří Kvita, Ph.D.Machine learning applications in high-energy and astroparticle physicsUniverzita Palackého v Olomouci, Přírodovědecká fakulta32. Physical Sciences
23-07152SYuliya VystavnaWater scarcity hotspots in Central Europe based on the composition of water isotopes in lakes: hydrological, climatic and socio-economic determinantsBiologické centrum AV ČR, v.v.i.32. Physical Sciences
23-07154Sprof. Ing. Pavel Lhoták, CSc.Chalcogen analogues of calix[n]arenes as novel macrocycles for supramolecular chemistryVysoká škola chemicko-technologická v Praze, Fakulta chemické technologie32. Physical Sciences
23-07169Sprof. Ing. Igor Jex, DrSc.Multipartite quantum dynamics on graphs and hypergraphs – theory and applicationsČeské vysoké učení technické v Praze, Fakulta jaderná a fyzikálně inženýrská32. Physical Sciences
23-07175Sdoc. Ing. Radovan Herchel, Ph.D.Semicoordination: a route to chemically stable molecular nanomagnetsUniverzita Palackého v Olomouci, Přírodovědecká fakulta32. Physical Sciences
23-07254Sprof. RNDr. Karel Lemr, Ph.D.Shape of mobility peaks as a tool for discrimination of isomers by ion mobility-mass spectrometryUniverzita Palackého v Olomouci, Přírodovědecká fakulta32. Physical Sciences
23-07310SProf. RNDr. Tomáš Pánek, Ph.D.Deciphering the largest rock spread on Earth: why in arid Patagonia?Ostravská univerzita, Přírodovědecká fakulta32. Physical Sciences
23-07334SIng. Štěpán Štverák, Dr.Plasma interaction effects on electron measurements on board Solar Orbiter spacecraftÚstav fyziky atmosféry AV ČR, v. v. i.32. Physical Sciences
23-07430Sprof. RNDr. Martin Kotora, CSc.Novel Kind of Full Carbon Planarly Chiral 3D Polyaromatics: Synthesis and ApplicationUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-07432SDr. techn. Eric Glowacki, MSc.Faraday’s Scalpel: electrochemical oxygen reduction for precise neural tissue ablationVysoké učení technické v Brně, Středoevropský technologický institut32. Physical Sciences
23-07457SMgr. David Kubizňák, Ph.D.Hidden Symmetries and Black Hole ChemistryUniverzita Karlova, Matematicko-fyzikální fakulta32. Physical Sciences
23-07499Sdoc. RNDr. Jana Bielčíková, Ph.D.Study of quark-gluon plasma with hard probes and limits of its formationÚstav jaderné fyziky AV ČR, v.v.i.32. Physical Sciences
23-07563SIng. Miroslav KrůsBoranes: A route to the inertial confinement of proton-boron fusion.Ústav fyziky plazmatu AV ČR, v. v. i.32. Physical Sciences
23-07565SIng. Ondřej Lengál, Ph.D.Representing Boolean Functions by a Self-Adaptable Data StructureVysoké učení technické v Brně, Fakulta informačních technologií32. Physical Sciences
23-07581SDoc. RNDr. Jiří Urban, Ph.D.Comprehensive top-down-bottom-up proteomicsMasarykova univerzita, Přírodovědecká fakulta32. Physical Sciences
23-07605Sdoc. Ernst Paunzen, PhDThe fate of Galactic open clustersMasarykova univerzita, Přírodovědecká fakulta22. Physical Sciences
23-07616Sprof. RNDr. Petr Nachtigall, Ph.D.Operando Modeling of Zeolites: Beyond the Chemical IntuitionUniverzita Karlova, Přírodovědecká fakulta32. Physical Sciences
23-07625SDr. sc. nat. Tomáš MagnaPre-Variscan oceanic basins of the Bohemian Massif - Integrating petrology, geochronology and non-traditional stable isotope systemsČeská geologická služba32. Physical Sciences
23-07703SMgr. Marek Piliarik, Ph.D.Label-free super-resolution microscopy based on single-protein fluctuations to study the assembly of tau protein envelopesÚstav fotoniky a elektroniky AV ČR, v.v.i.32. Physical Sciences
23-07821SMgr. Pavlína Hasalová, Ph.D.Pervasive melt migration in continental crust: a micro-scale process with large-scale implicationsČeská geologická služba32. Physical Sciences
23-07931SDavid Fernández DuqueTransfinite Certificates of ConvergenceÚstav informatiky AV ČR, v.v.i.32. Physical Sciences
23-07947SMgr. Jakub Mareček, Ph.D.Learning Models of Quantum Systems as a Non-Commutative Polynomial Optimization ProblemČeské vysoké učení technické v Praze, Fakulta elektrotechnická32. Physical Sciences
23-08049SDr. Ulf BüntgenCentral European HYDRoclimate from Oak stable isotopes over the past 8000 years – HYDRO8Ústav výzkumu globální změny AV ČR, v. v. i.32. Physical Sciences
23-08056Sprof. Ing. Mgr. Miroslav Trnka, Ph.D.Dynamic tracking of drought events and their classification on the global scale - DynamicDroughtÚstav výzkumu globální změny AV ČR, v. v. i.32. Physical Sciences
23-08249SRNDr. Pavla Štípská, Ph.D.Origin of the relaminant in the Bohemian Massif during the Variscan orogenyČeská geologická služba32. Physical Sciences
23-04655Sprof. PharmDr. Karel Šmejkal, Ph.D.Role of prenylation and glycosylation patterns in anti-inflammatory activity and metabolism of natural phenolic compoundsMasarykova univerzita, Farmaceutická fakulta33. Medical and Biological Sciences
23-04662Sprof. RNDr. Zdeněk Dvořák, Ph.D., DrSc.Dietary monoterpenoids as a novel class of aryl hydrocarbon receptor negative allosteric modulators in the therapy of colon cancerUniverzita Palackého v Olomouci, Přírodovědecká fakulta33. Medical and Biological Sciences
23-04670SMgr. Jan Jakubík, Ph.D.Structure-activity guided design of novel long-acting antagonists of muscarinic receptorsFyziologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-04671Sprof. Ing. Jiří Neužil, CSc.Metabolic switch in liver regenerationBiotechnologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-04686SRNDr. Veronika Obšilová, Ph.D.The role of calcium and 14-3-3 protein in the regulation of human ubiquitin ligase Nedd4-2Fyziologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-04755SMgr. et Mgr. Dalibor Blažek, Ph.D.Characterization of a new pathway regulating pre-mRNA splicingMasarykova univerzita, Středoevropský technologický institut33. Medical and Biological Sciences
23-04769Sprof. M.Sc. Vjačeslav Jurčenko, Ph.D.Telomere biology of trypanosomatids: contrasting features point to diverse strategiesOstravská univerzita, Přírodovědecká fakulta33. Medical and Biological Sciences
23-04876Sdoc. RNDr. Marcela Buchtová, Ph.D.Nanodiamonds as selective protein traps to regulate disorders caused by aberrant FGF2 signalingMasarykova univerzita, Přírodovědecká fakulta33. Medical and Biological Sciences
23-04918SDr. Nicola SilvaA Chromatin Modification-mediated Mechanism Illuminates a Novel Pathway for the Establishment of Meiotic Chromosome SynapsisMasarykova univerzita, Lékařská fakulta33. Medical and Biological Sciences
23-04922Sprof. MUDr. Ladislav Vyklický, DrSc.In vitro and in vivo study of the consequences of disease-associated mutations in the NMDA receptor and potential rescue pharmacologyFyziologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-05070Sprof. PharmDr. Alena Sumová, CSc., DSc.Development of circadian clocks in neurons and glia of the fetal brain and their sensitivity to maternal stressFyziologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-05257Sdoc. Mgr. Zbyněk Heger, Ph.D.Ferritin-based prodrugs as nanovaccines for synergic immunotherapy of solid tumorsVysoké učení technické v Brně, Středoevropský technologický institut33. Medical and Biological Sciences
23-05274Sprof. MUDr. Milan Brázdil, Ph.D.Therapeutic miRNA targeting in epilepsy: Impact on excitability and beyondMasarykova univerzita, Středoevropský technologický institut33. Medical and Biological Sciences
23-05284Sdoc. Mgr. Jan Paleček, Dr. rer. natDeciphering the relationship between homologous recombination and gene silencingMasarykova univerzita, Přírodovědecká fakulta33. Medical and Biological Sciences
23-05303SMgr. Štěpána Boukalová, Ph.D.Exploiting metabolic vulnerabilities in succinate dehydrogenase-deficient cancersBiotechnologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-05327SIng. Lukáš Valihrach, Ph.D.Astrocyte-microglia communication as a target for stroke therapyBiotechnologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-05377Sprof. MUDr. Pavel Klener, Ph.D.Single-cell transcriptomics for the analysis of subclonal heterogeneity and clonal evolution of mantle cell lymphomaUniverzita Karlova, 1. lékařská fakulta33. Medical and Biological Sciences
23-05389SRNDr. Miroslav Kvasnica, Ph.D.Novel CB2 and BChE modulators against Parkinson's disease and related pathologiesÚstav experimentální botaniky AV ČR, v.v.i.33. Medical and Biological Sciences
23-05462Sdoc. RNDr. Vladimír Kryštof, Ph.D.Targeting of FLT3 using new dual inhibitors as a therapeutic approach in MLL-rearranged acute myeloid leukemiaUniverzita Palackého v Olomouci, Přírodovědecká fakulta33. Medical and Biological Sciences
23-05474Sprof. Ing. Miroslav Strnad, CSc., DSc.Modulation of kinases for targeted treatment of haematological and other malignanciesUniverzita Palackého v Olomouci, Přírodovědecká fakulta33. Medical and Biological Sciences
23-05540SDr. Jessica Kwok, PhD.Modulation of extracellular matrix to enhance neuroplasticity for the rescue of age-related memory deficits.Ústav experimentální medicíny AV ČR, v.v.i.33. Medical and Biological Sciences
23-05609SKari Hemminki, M.D. Ph.D.Explaining metastatic potential of colorectal cancer through whole-exome sequening and immune cell and telomere landscapeUniverzita Karlova, Lékařská fakulta v Plzni33. Medical and Biological Sciences
23-05622SMgr. Jarmila Hnilicová, Ph.D.Novel regulatory RNAs interacting with the transcription machinery in bacteriaMikrobiologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-05634SRNDr. Branislav Večerek, PhD.Contribution of regulatory RNAs to the pathogenesis of Bordetella pertussisMikrobiologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-05645SMgr. Klára Kostovčíková, Ph.D.Experimental ketogenic diet effect on immune response and ability of organism to cope with foreign substances (xenobiotics) in experimental modelMikrobiologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-05764Sprof. Mgr. Marek Eliáš, Ph.D.Organellar translation as an evolutionary playgroundOstravská univerzita, Přírodovědecká fakulta33. Medical and Biological Sciences
23-05805SRNDr. Lenka Žáková, Ph.D.Mannose-6-phosphate/insulin-like growth factor 2 receptor ligands to study their in vitro effects in pathological and neural processesÚstav organické chemie a biochemie AV ČR, v.v.i.33. Medical and Biological Sciences
23-05857SMgr. Eugenie Nepovimová, Ph.D.Alzheimer´s disease and aging: can mTOR inhibitors kill two birds with one drug?Univerzita Hradec Králové, Přírodovědecká fakulta33. Medical and Biological Sciences
23-05951SPhilip John Coates, Ph.D.Mechanisms and Effects of Inverse TAp63 and ΔNp63 RegulationMasarykův onkologický ústav33. Medical and Biological Sciences
23-05963SRNDr. Gabriela Pavlínková, Ph.D.Transcriptional and epigenetic regulation of auditory neuron developmentBiotechnologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06027SRNDr. Lukáš Alán, PhDThe role of Vwa8 protein in the regulation of mitochondrial lipid metabolismFyziologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06051SMgr. Tomáš Perečko, PhDElectrophilic nitro-fatty acids as countermeasures of ionizing radiation-induced hematopoietic damage: targeting NRF2 pathwayBiofyzikální ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06129Sdoc. Mgr. David Staněk, Ph.D.Identification of molecular defects caused by mutations in splicing factors linked with retina degenerationÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-06160SMgr. Jan Křivánek, Ph.D.Fluctuation of the stem cell niche as a source of tissue adaptability in health and diseaseMasarykova univerzita, Lékařská fakulta33. Medical and Biological Sciences
23-06208SRNDr. Katarína Smolková, Ph.D.Targeting tamoxifen resistance in breast carcinoma: the role of glycerophospholipid metabolismFyziologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06269SIng. Miroslava Anděrová, CSc.Disturbed regulation of mTOR signaling in glial cells following cerebral ischemiaÚstav experimentální medicíny AV ČR, v.v.i.33. Medical and Biological Sciences
23-06295SIng. Jan Dohnálek, Ph.D.Where transcription meets translationBiotechnologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06299Sprof. RNDr. Petr Volf, CSc.Transmission cycles of Leishmania major in natural reservoir hosts: local analyses with global implicationsUniverzita Karlova, Přírodovědecká fakulta33. Medical and Biological Sciences
23-06307SMgr. Vojtěch Novohradský, PhD.Metal-based compounds as candidates for antimetastatic chemotherapyBiofyzikální ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06316Sprof. RNDr. Jana Kašpárková, Ph.D.Medicinal biophysics and biochemistry of light-activated metallodrugs for targeted cancer therapy.Biofyzikální ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06368SRNDr. Libuše Váchová, CSc.Intercellular coordination and competition in spatially-structured yeast populations: Processes and regulationsMikrobiologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06472SMgr. Karel Souček, Ph.D.Elucidation of Haspin kinase interactome and its role in the context of cell plasticityBiofyzikální ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-06536SMgr. Ivo Fabrik, Ph.D.Pnpt1 as a regulator of metabolic reprogramming in phagocytesFakultní nemocnice Hradec Králové33. Medical and Biological Sciences
23-06546SRNDr. Tomáš Petrásek, Ph.D.The role of parvalbumin-positive interneurons in a rat model of schizophrenia induced by maternal immune activationNárodní ústav duševního zdraví33. Medical and Biological Sciences
23-06558SDoc. PharmDr. Martin Štěrba, Ph.D.Anthracycline-induced DNA damage signaling in the heart: implications for cardiotoxicity development and its pharmacological modulationsUniverzita Karlova, Lékařská fakulta v Hradci Králové33. Medical and Biological Sciences
23-06571SMgr. Karel Doležal, Dr., DSc.What orang-utans can teach us: plants used for self-medication as a potential source of bioactive substances with amoebicidal and antigiardial effectsÚstav experimentální botaniky AV ČR, v.v.i.33. Medical and Biological Sciences
23-06605SRNDr. Dominik Filipp, CSc.Interplay of cytoskeleton and membrane morphology during formation of immunological synapseÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-06638SRNDr. Jan Dvořák, Ph.D.Schistosoma mansoni egg-secreted proteins: a comparative approach to identify bioactive molecules of a human parasite.Česká zemědělská univerzita v Praze, Fakulta agrobiologie, potravinových a přírodních zdrojů33. Medical and Biological Sciences
23-06675Sdoc. RNDr. Petr Vaňhara, Ph.D.Pulmonary stress and regenerationMasarykova univerzita, Lékařská fakulta33. Medical and Biological Sciences
23-06676SMgr. Tomáš Brdička, Ph.D.Adaptor protein PSTPIP2 and chronic multifocal osteomyelitis in mouse models and human patientsÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-06884SRNDr. Bořivoj Vojtěšek, DrSc.Characterization of the ribosome translating pre-spliced mRNAs for the synthesis of antigenic peptide substrates for the MHC-I pathwayMasarykův onkologický ústav33. Medical and Biological Sciences
23-06888SMgr. Pavel Doležal, Ph.D.Iron-sulfur cluster biosynthesis in Giardia intestinalis mitosomes and their role in cellular metabolism and antibiotic resistance.Univerzita Karlova, Přírodovědecká fakulta33. Medical and Biological Sciences
23-06913SKonstantinos Tripsianes, Ph.D.Understanding the order-disorder continuum in Dishevelled function and Wnt signalingMasarykova univerzita, Středoevropský technologický institut33. Medical and Biological Sciences
23-07021Sprof. MUDr. David Šmajs, Ph.D.In vitro cultivation of Treponema pallidum: a new tool to study genetics and pathogen-host interaction of the agent of syphilisMasarykova univerzita, Lékařská fakulta33. Medical and Biological Sciences
23-07056SRNDr. Zbyněk Kozmik, CSc.Evolutionary history of vertebrate lateral plate mesoderm: an insight from the basal chordate amphioxusÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07074SIng. Mgr. Jaroslav Hlinka, Ph.D.Symmetries of brain connectivityNárodní ústav duševního zdraví33. Medical and Biological Sciences
23-07094Sprof. PharmDr. František Štaud, Ph.D.Cannabis use in pregnancy; effects on endocrine and immune functions of the placentaUniverzita Karlova, Farmaceutická fakulta v Hradci Králové33. Medical and Biological Sciences
23-07096SIng. Kvido Stříšovský, Ph.D.Mechanistic and structural analysis of the ADAM17-iRhom2 complex for novel anti-inflammatory strategiesÚstav organické chemie a biochemie AV ČR, v.v.i.33. Medical and Biological Sciences
23-07141SPanagiotis Alexiou, PhDA computational-experimental approach to non-miRNA Ago2 targetingMasarykova univerzita, Středoevropský technologický institut33. Medical and Biological Sciences
23-07149SRNDr. Cyril Bařinka, Ph.D.Mechanistic insights into microtubule polyglutamylations by tubulin tyrosine ligase-like 11 (TTLL-11)Biotechnologický ústav AV ČR, v.v.i.33. Medical and Biological Sciences
23-07160Sprof. RNDr. Daniel Růžek, Ph.D.Molecular pathogenesis of alimentary infection by tick-borne encephalitis virus.Masarykova univerzita, Přírodovědecká fakulta33. Medical and Biological Sciences
23-07184Sdoc. RNDr. Jiří Novotný, DSc.Circadian regulation of kynurenine pathway enzymes in rat brain and peripheral organsUniverzita Karlova, Přírodovědecká fakulta33. Medical and Biological Sciences
23-07212SMgr. Vladimír Soukup, Ph.D.New organizers of development of body appendages in vertebratesUniverzita Karlova, Přírodovědecká fakulta33. Medical and Biological Sciences
23-07273SMUDr. Jiří Bártek, CSc., Dr.h.c.Exploring the role of PML nucleolar compartment in rDNA maintenance in normal and cancer cellsÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07277SMgr. Vladimír Hampl, Ph.D.Spatial proteomics of Euglena gracilis with a focus on its pellicle structure and chloroplast protein importUniverzita Karlova, Přírodovědecká fakulta33. Medical and Biological Sciences
23-07370SMgr. Vladimír Varga, PhDStarvation as a trigger of cellular differentiation of Trypanosoma brucei procyclic formÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07372Sprof. Mgr. Štěpánka Vaňáčová, Ph.D.Identification and role of RNA surveillance and degradation factors in the regulation of gene expressionMasarykova univerzita, Středoevropský technologický institut33. Medical and Biological Sciences
23-07396SDr. Teije Middelkoop, PhDConverting molecular-scale torques to organismal left-right symmetry breakingÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07532SRNDr. Dávid Drutovič, Ph.D.Regulation of acentriolar spindle assembly and chromosome segregation in human and mouse oocyte meiosisÚstav živočišné fyziologie a genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07631SMgr. Michaela Bosáková, Ph.D.The function of GRK2 kinase in skeletogenesis and bone homeostasisÚstav živočišné fyziologie a genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07674Sdoc. Hassan Hashimi, Ph.D.How systematic changes to the membrane proteome and cardiolipin drive mitochondrial cristae developmentBiologické centrum AV ČR, v.v.i.33. Medical and Biological Sciences
23-07736SRNDr. Petr Dráber, DrSc.New signaling pathways induced in mast cells by cholesterol-dependent cytolysinsÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07810SMgr. Michaela Fenckova, PhDDrosophila habituation to close the gap in genetic diagnostics of neurodevelopmental disordersJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta33. Medical and Biological Sciences
23-07850SRNDr. Daniel Sojka, Ph.D.Master proteases driving the apical complex of Babesia parasitesBiologické centrum AV ČR, v.v.i.33. Medical and Biological Sciences
23-07990SRNDr. Roman Kuchta, Ph.D.Secretomics: exploration of intercellular communicators between parasites and their hostsBiologické centrum AV ČR, v.v.i.33. Medical and Biological Sciences
23-08039SRNDr. Martin Palus, Ph.D.Neuropathogenesis linked to NS1 protein of tick-borne encephalitis virusBiologické centrum AV ČR, v.v.i.33. Medical and Biological Sciences
23-04719Sdoc. Mgr. Markéta Ziková, Ph.D.Development of Syllabic Sonorants in CzechMasarykova univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-04764SMgr. Jana Obrovská, Ph.D.Addressing the Individual Educational Needs of All Students: Ethnography of Lower Secondary ClassroomsMasarykova univerzita, Pedagogická fakulta34. Social Sciences and Humanities
23-04781SProf. PhDr. Pavel ZatloukalFrom the Obelisk to Moderation. Brno Architecture of the Nineteenth CenturyOstravská univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-04833Sdoc. Mgr. Tomáš Weiss, M.A., Ph.D.Specialisation in EU small states’ foreign and security policyUniverzita Karlova, Fakulta sociálních věd34. Social Sciences and Humanities
23-04955Sdoc. PhDr. Věra Stojarová, Ph.D.Russian influence operations in the Western Balkans and their impact on the Western Balkan Security ComplexMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-04979Sdoc. Mgr. Martin Pelc, Ph.D.Schlaraffia: The Element of Play in Nineteenth-century CultureSlezská univerzita v Opavě, Filozoficko-přírodovědecká fakulta34. Social Sciences and Humanities
23-04980SIng. Mgr. Petr Pytlík, Ph.D.The function of paratexts at the reception of authors of the Gruppe 47 in Czechoslovakia between 1948-1989Masarykova univerzita, Pedagogická fakulta34. Social Sciences and Humanities
23-04986SMgr. Klára Bártová, Ph.D. et Ph.D.Sexual orientation or not? Capturing the diversity of cognitive, psychosocial, and psychophysiological aspects of asexualityUniverzita Karlova, Fakulta humanitních studií34. Social Sciences and Humanities
23-04988Sdoc., Mgr. Miroslav Valeš, Ph.D.A Fala Grammar Based on Primary Data and Community EngagementTechnická univerzita v Liberci, Fakulta přírodovědně-humanitní a pedagogická34. Social Sciences and Humanities
23-04989SMgr. Marie Peterková Hlouchová, Ph.D.Ancient Egyptian Burial Containers of the Old Kingdom and First Intermediate Period. Evolution, Contextualisation and SignificanceUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-05005SFil.dr Mgr. Anežka KuzmičováWays of imagining with children’s nature nonfiction (WONDER)Univerzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-05042SMgr. Radka Heisslerová, Ph.D."Czech Vasari" Jan Jakub Quirin Jahn (1739–1802) and his conception of the history of visual arts in BohemiaNárodní galerie v Praze34. Social Sciences and Humanities
23-05045SPhDr. Bc. Věra Dvořáčková, Ph.D.Symbols of Science 1945–1970Masarykův ústav a Archiv AV ČR, v.v.i.34. Social Sciences and Humanities
23-05047Sdoc. PhDr. Iva Šmídová, Ph.D.Institutions of Ageing MenMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-05096SRNDr. Robert Osman, Ph.D.Geographies of Crip Temporalities: Time in Everydayness of People with DisabilitiesMasarykova univerzita, Přírodovědecká fakulta34. Social Sciences and Humanities
23-05138SMgr. Adéla Ebersonová, Ph.D.Medieval Libraries of the Canons Regular of St Augustine in Bohemia in the Context of Central EuropeUniverzita Karlova, Fakulta humanitních studií34. Social Sciences and Humanities
23-05178SMgr. Matyáš Havrda, Ph.D.Credible medicine: Galen's method of inquiry and proofFilosofický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-05181Sdoc. PhDr. Jana Mynářová, Ph.D.Archaeology of Texts. Tradition, Transmission, and Transformation in the Ancient Near EastUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-05238SMgr. et Mgr. Marie Mikulová, Ph.D.Functions and forms of circumstantial modificationsUniverzita Karlova, Matematicko-fyzikální fakulta34. Social Sciences and Humanities
23-05240SMgr. Barbora Štěpánková, Ph.D.Epistemic and Evidential Markers in CzechUniverzita Karlova, Matematicko-fyzikální fakulta34. Social Sciences and Humanities
23-05243SAlberto Virdis, Ph.D.Fragmented Images. Exploring the Origins of Stained Glass ArtMasarykova univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-05248SPhDr. Jan Mergl, Ph.D.Circulation of knowledge as a basis for multiculturalism and its role in a transformation of the Czech art Industry in 1850s–1920sUměleckoprůmyslové muzeum v Praze34. Social Sciences and Humanities
23-05300SMgr. Eva Taterová, M.A., Ph.D.Czechoslovak Diplomacy and the Arab-Israeli Conflict from 1948-1989Ústav pro soudobé dějiny AV ČR, v.v.i.34. Social Sciences and Humanities
23-05312Sdoc. PhDr. Petr Hlaďo, Ph.D.Research on perceived work ability among lower secondary school teachersMasarykova univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-05334SMgr. Pavel Burgert, Ph.D.Metabasites of the Jizerské Hory (Jizera Mountain) Type as a Trans-Cultural Link Between Central European Prehistoric CommunitiesArcheologický ústav AV ČR, Praha, v.v.i.34. Social Sciences and Humanities
23-05374SMgr. Filip Jaroš, Ph.D.Reframing Philosophical Anthropology: Searching for an Anthropological Difference Beyond the Nature/Culture DichotomyUniverzita Hradec Králové, Filozofická fakulta34. Social Sciences and Humanities
23-05379SZsófia Csajbók, M.A., Ph.D.Exploring the dynamics of depressive symptoms in intimate relationshipsUniverzita Karlova, Fakulta humanitních studií34. Social Sciences and Humanities
23-05408SMgr. Vít Třebický, Ph.D.Attractiveness cues to physical fitness across perceptual modalitiesUniverzita Karlova, Fakulta tělesné výchovy a sportu34. Social Sciences and Humanities
23-05437SPhDr. Dalibor Dobiáš, Ph.D.Literary criticism in the Bohemian lands in the period of the formation of national canons (1806-1858)Ústav pro českou literaturu AV ČR, v.v.i.34. Social Sciences and Humanities
23-05448Sprof. PhDr. Vojtěch Kolman, Ph.D.Fallibilism and Its Immanent StructureUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-05449Sdoc. Bernadette Nadya Jaworsky, Ph.D.People Like Us? A Reverse Sociology of Migration in CzechiaMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-05519SRNDr. Šárka Kaňková, Ph.D. Disgust sensitivity before and after conception: immunological and hormonal correlates and long-term effects on maternal and child healthUniverzita Karlova, Přírodovědecká fakulta34. Social Sciences and Humanities
23-05562SMgr. et Mgr. Michaela Spurná, Ph.D.Who teaches future geography teachers? Social representations of teachers and teaching in initial teacher educationMasarykova univerzita, Pedagogická fakulta34. Social Sciences and Humanities
23-05587Sdoc. PhDr. Daniel Špelda, Ph.D.Philosophical Legitimation of Science in the Early Enlightenment: Fontenelle and His ContemporariesMasarykova univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-05617Sdoc. Mgr. Petr Knecht, Ph.D.Conceptions of geography teaching: Exploring the ecological validity of an assessment toolMasarykova univerzita, Pedagogická fakulta34. Social Sciences and Humanities
23-05637SMgr. Viktor Ber, Ph.D.Capital offences in the Deuteronomic Code, and their early linguistic recontextualizationJihočeská univerzita v Českých Budějovicích, Teologická fakulta34. Social Sciences and Humanities
23-05641SMgr. Pavel Baloun, Ph.D.Punish or rehabilitate? Gender, convict labour, and disciplination in the workhouse in the Czech lands (1918-1950)Historický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-05655SMgr. Martin Lang, Ph.D.Signaler psychology: Investigating computations underlying human cooperative communicationMasarykova univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-05753SMgr. Jiří Hlaváček, Ph.D.Minutes between life and death: Changes in emergency medical service and the professional identity of its employees in the Czech lands 1952–2003Ústav pro soudobé dějiny AV ČR, v.v.i.34. Social Sciences and Humanities
23-05769SPhDr Ayaz Zeynalov, PhDWeathering Corporate Bankruptcy: The Role of Discipline EffectVysoká škola ekonomická v Praze, Fakulta mezinárodních vztahů34. Social Sciences and Humanities
23-05777SPetr JakubíkNew challenges in macroprudential policies for the European insurance sectorUniverzita Karlova, Fakulta sociálních věd34. Social Sciences and Humanities
23-05800SMgr. David Černín, Ph.D.The Big History and its Philosophical PotentialOstravská univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-05873SMartin Komarc, Ph.D.Motivation for physical education in Czech high school students: Longitudinal associations with psychosocial antecedents and cognitive outcomesUniverzita Karlova, Fakulta tělesné výchovy a sportu34. Social Sciences and Humanities
23-05880Sdoc. Mgr. Aleš Urválek, Ph.D.Intercultural and interdisciplinary transfer on the border of historical epochs: the intellectual biography of Joachim MorasMasarykova univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-05893SMgr. Miroslav Hanke, Ph.D.On Knowing and Doubting: The Tradition of British Epistemic Logic in Late-Medieval PeriodFilosofický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-05924SMgr. Jana Nosková, Ph.D.Between "East" and "West" – border experiences and narratives on the Czech-Slovak and Slovak-Ukrainian state bordersEtnologický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-05958Sdoc. Mgr. Monika Brusenbauch Meislová, Ph.D.Self-Legitimation Practices of EU Institutions in an Age of Permanent Emergency: A Discursive PerspectiveMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-06062SMgr. Petr Kadlec, Ph.D.The modernisation of commercial education in Cisleithania 1848-1918: patterns, trends, processesOstravská univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-06139SMgr. Vladimír Holý, Ph.D.Dynamic Score-Driven Models in Operations ResearchVysoká škola ekonomická v Praze, Fakulta informatiky a statistiky34. Social Sciences and Humanities
23-06150SMgr. Tereza Matějčková, Ph.D.Repetition: The Mother of Originality? Copying and Its Uncertain PromiseUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-06170Sdoc. Mgr. Sylvie Graf, Ph.D.The Role of Distinct Types of Social Norms in Improving Conflictual Intergroup RelationsPsychologický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-06180SMgr. Jaromír Mazák, Ph. D.The Impact of the Legitimacy of Civil Society Organizations on Volunteering: The Case of Czechia in a Post-Communist ContextUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-06187SMgr. Stanislav Popelka, Ph.D.Identification of barriers in the process of communication of spatial socio-demographic informationUniverzita Palackého v Olomouci, Přírodovědecká fakulta34. Social Sciences and Humanities
23-06213SSmaranda PanteaDigitalization of the public sector: effects on growth and innovation of domestic IT sectorsVysoká škola ekonomická v Praze, Fakulta mezinárodních vztahů34. Social Sciences and Humanities
23-06243SJUDr. Miroslav Sedláček, Ph.D., LL.M.Digital Resolution of Civil Disputes and Guarantee of the Right to a Due ProcessUniverzita Karlova, Právnická fakulta34. Social Sciences and Humanities
23-06264SPhDr. Martina Mysíková, Ph.D.Income poverty: Household expenses and indebtedness in European countriesSociologický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-06280SMichal HolčapekNew approaches to forecasting of financial time series within fuzzy-probabilistic settingOstravská univerzita, Centrum excelence IT4Innovations, divize OU, Ústav pro výzkum a aplikace fuzzy modelování34. Social Sciences and Humanities
23-06282SDr. Fabio Giovanni LamantiaEvolutionary economic dynamics with finite populations: Modeling and applicationsVysoká škola báňská - Technická univerzita Ostrava, Ekonomická fakulta34. Social Sciences and Humanities
23-06289SPhDr. Lenka Kollerová, Ph.D.Consequences of bullying: How classroom characteristics weaken the psychological problems associated with victimizationPsychologický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-06346SJakub Eberle, Ph.D.Digital Sovereignty and Central EuropeÚstav mezinárodních vztahů, v.v.i.34. Social Sciences and Humanities
23-06348SMgr. et Mgr. Marcela Petrová Kafková, Ph.D.Meanings of food intake in old ageMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-06394SMgr. Jan Kapusta, Ph.D.Key cultural sources, ideas, and practices of Western alternative spirituality and medicineZápadočeská univerzita v Plzni, Fakulta filozofická34. Social Sciences and Humanities
23-06403SMgr. Helena Tůmová, Ph.D.Provenance of Marble from Northern Italy and Istria as Evidence of Interconnections between the East and West in Late AntiquityUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-06406SMgr. Kamila Hladikova, Ph.D.Representations and Role of Tibetan Buddhism in Narratives about Tibet from 1950s to PresentUniverzita Palackého v Olomouci, Filozofická fakulta34. Social Sciences and Humanities
23-06411SIng. Zbyněk Dubský, Ph.D.Decarbonisation of the Czech energy sector through the prism of the new energy geopolitics of the EU (focusing on gas dependence)Vysoká škola ekonomická v Praze, Fakulta mezinárodních vztahů34. Social Sciences and Humanities
23-06509Sdoc. Mgr. et Mgr. Markéta Kulhánková, Ph.D.Cherchez la femme. Female Characters in Late Byzantine LiteratureSlovanský ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-06606Sprof. PhDr. Ladislav Krištoufek, Ph.D.Deep dive into decentralized finance: Market microstructure, and behavioral and psychological patternsÚstav teorie informace a automatizace AV ČR, v.v.i.34. Social Sciences and Humanities
23-06645SMgr. Iva Lelková, Ph.D.Scholarly publication strategies and correspondence networks of the post-White Mountain Czech Lands (1622 - 1667)Filosofický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-06662SMSc. Kateřina Klapilová, Ph.D.Body or behavior? Exploring the relative roles of physical versus behavioral indicators of age in mating contexts in pedophiles and teleiophilesNárodní ústav duševního zdraví34. Social Sciences and Humanities
23-06683SMgr. et Mgr. Adéla Souralová, Ph.D.Grandparent-Grandchild Bonds: Cross-Generation Relations and Everyday Negotiations of Care CommitmentsMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-06790SJUDr. Martin Hapla, Ph.D.Human Rights and WelfarismMasarykova univerzita, Právnická fakulta34. Social Sciences and Humanities
23-06796SJames BrandCze-Lex: A large-scale quantification of the Czech lexiconUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-06812SMgr. Jana Urbanovská, Ph.D.Images of “the Other”: Czech-German relations in times of crisisMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-06822SMgr. Rebeka Rmoutilová, Ph.D.Human skeletal remains from Zlaty kůň: The re-examination and new interpretations of the 20th century excavations at Koněprusy CavesUniverzita Karlova, Přírodovědecká fakulta34. Social Sciences and Humanities
23-06827Sprof. Dr. phil. Jakub Mácha, Ph.D.The Ornament: Aesthetics, Politics and Metaphysics of RepetitionMetropolitní univerzita Praha, o.p.s.34. Social Sciences and Humanities
23-06828Sdoc. Mgr. Jakub Čapek, Ph.D.The Reluctant Existentialism of Jan PatočkaUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-06902SMgr. Dušan Coufal, Th.D.The Controversy over Wyclif and his 45 Articles in a European PerspectiveFilosofický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-06924SMgr. Hynek Cígler, Ph.D.Response-scale format effects on the psychometric parameters of itemsMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-06940Sdoc. Mgr. Ondřej Chvojka, Ph.D.Unity across the border. Indicators of economic and social relations of the Urnfield Period in the Bohemian-Bavarian areaJihočeská univerzita v Českých Budějovicích, Filozofická fakulta34. Social Sciences and Humanities
23-06953SMgr. Michal Schwarz, Ph.D.Evolutionary interferences of religion and governance in Inner Asia: comparison of mutual impacts with tributary countries: Mongolia, Korea, VietnamMasarykova univerzita, Filozofická fakulta34. Social Sciences and Humanities
23-06972SMgr. Daniela Theinová, Ph.D.Green Ireland? Ecology in Modern Irish PoetryUniverzita Karlova, Filozofická fakulta34. Social Sciences and Humanities
23-06989SMgr. et Mgr. Ing. Štěpán Bahník, Ph.D.Why don't birds of a feather always flock together? Imperfect selection of cheaters in cheating-enabling environmentsVysoká škola ekonomická v Praze, Fakulta podnikohospodářská34. Social Sciences and Humanities
23-07020SMgr. Lucie Drdova, Ph.D.BDSM under-CoV-2: The Central European BDSM subculture during the pandemicUniverzita Hradec Králové, Pedagogická fakulta34. Social Sciences and Humanities
23-07049SMgr. Jan Kovář, Ph.D.Mapping and Explaining the Politicisation and Framing of European Integration in the Political Discourse of Central and Eastern European CountriesÚstav mezinárodních vztahů, v.v.i.34. Social Sciences and Humanities
23-07068SMgr. Petr Dvořák, Ph.D.Moral Argument in Juan Caramuel y Lobkowicz in the Context of ProbabilismFilosofický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-07081SSebastian OttingerThe Effects and Origins of National and Local Political InstitutionsUniverzita Karlova, Centrum pro ekonomický výzkum a doktorská studia34. Social Sciences and Humanities
23-07114SMgr. et Mgr. Jiří Navrátil, Ph.D.Between revolution and crisis: Emergence, evolution and re-structuring of economic protest in post-socialist contextMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-07119Sprof. RNDr. Jaroslav Peregrin, CSc.MEANING AS AN OBJECT – PRINCIPLES OF SEMANTIC THEORIESFilosofický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-07128SDr. Gabriele TorriMarket based measures of systemic risk using synthetic CDOsVysoká škola báňská - Technická univerzita Ostrava, Ekonomická fakulta34. Social Sciences and Humanities
23-07136SIng. Matej Lorko, PhD.Three experiments on using salience towards sustainable tax complianceVysoká škola ekonomická v Praze, Fakulta podnikohospodářská34. Social Sciences and Humanities
23-07198SPhDr. Ivana Boháčová, Ph.D.An Early Medieval Centre – Topography, Functions, Changes: Přemyslid Boleslav and its transformation into the seat of a collegiate chapter (900–1200)Archeologický ústav AV ČR, Praha, v.v.i.34. Social Sciences and Humanities
23-07227SMgr. Milan Řepa, Ph.D.The Politics and Collective Identities of Bohemian Germans (1848-1914)Historický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-07257SMgr. Jan Urban, Ph.D.Causal role of environmental identity in pro-environmental behaviorUniverzita Karlova, Centrum pro otázky životního prostředí34. Social Sciences and Humanities
23-07270SIng. Miroslav Rada, Ph.D.Using modern methods of discrete geometry for solving selected problems in operations research and data analysis – IIIVysoká škola ekonomická v Praze, Fakulta informatiky a statistiky34. Social Sciences and Humanities
23-07295Sdoc. PhDr. Jan Mervart, Ph.D.A Genealogy of Czechoslovak Stalinism 1929–1953: Conceptualizations, Representations, CommunicationsFilosofický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-07318Sdoc. PhDr. Ondřej Sládek, Ph.D.Czech Structuralism Between Poetics and PoliticsÚstav pro českou literaturu AV ČR, v.v.i.34. Social Sciences and Humanities
23-07353SGiedrė Šabasevičiūtė, Ph.D.Pathways of Literary Professionalization in Twenty-first-century EgyptOrientální ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-07371Sdoc. Ing. Mgr. Martin Lux, Ph.D.Pragmatic socioeconomics: a new bridge between sociology and economics in housing studiesSociologický ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-07378Sprof. PhDr. Martin Kreidl, M.A.,Ph.D.The changing educational structure and new partnership dynamics: Highly educated women after the reversal of the gender gap in educationMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-07382SMgr. Stanislav MartinátAccumulating Environmental Injustices and the Emergence of Climate Vulnerability in Central-European Coal Regions: Socio-Spatial PerspectivesUniverzita Palackého v Olomouci, Přírodovědecká fakulta34. Social Sciences and Humanities
23-07559SMgr. Matouš Jaluška, Ph.D.Verbal Efficacy in Literature of Medieval BohemiaÚstav pro českou literaturu AV ČR, v.v.i.34. Social Sciences and Humanities
23-07619SMgr. Michaela Langová, Ph.D.Pottery as a Witness to Cultural Change? The Early Bronze Age Settlement Agglomeration in Plotiště n. Labem in the Light of Multidisciplinary ResearchArcheologický ústav AV ČR, Praha, v.v.i.34. Social Sciences and Humanities
23-07642SVasily Korovkin, Ph.D.The Effects of Wars and Conflicts on Production Networks: Evidence from Russia, Ukraine, and IndiaNárodohospodářský ústav AV ČR, v.v.i.34. Social Sciences and Humanities
23-07660SMgr. Martin Voříšek, Ph.D.Schwarzenberg Wind Harmonie in the musical life of the princely court at the second half of the 18th centuryJihočeská univerzita v Českých Budějovicích, Pedagogická fakulta34. Social Sciences and Humanities
23-07669SMgr. Veronika Jičínská, Ph. D.Women's Writing and Translating in Fin-de-Siècle Prague and the Bohemian LandsUniverzita Jana Evangelisty Purkyně v Ústí nad Labem, Filozofická fakulta34. Social Sciences and Humanities
23-07727SMgr. Petr Plecháč, Ph.D.European Poetry: Distant ReadingÚstav pro českou literaturu AV ČR, v.v.i.34. Social Sciences and Humanities
23-07747SPhDr. Martin Loučka, Ph.D.Hope and prognostic awareness in patients with advanced diseaseUniverzita Karlova, 3. lékařská fakulta34. Social Sciences and Humanities
23-07764SMgr. Alžběta Frank Danielisová, Ph.D.Social and technological change along the Amber Road in the third century BC. Multi-isotopic and aDNA analysis of La Tène cemeteries in Moravia.Archeologický ústav AV ČR, Praha, v.v.i.34. Social Sciences and Humanities
23-07791Sprof. JUDr. Michal Skřejpek, DrSc.Rituals and Symbols in Roman LawUniverzita Karlova, Právnická fakulta34. Social Sciences and Humanities
23-07819Sprof. RNDr. Petr Pavlínek, Ph.D.Impacts of the transition to the manufacturing of electric vehicles in the Czech automotive industryUniverzita Karlova, Přírodovědecká fakulta34. Social Sciences and Humanities
23-07863SPhDr. Rudolf Procházka, CSc.Emergence of the high medieval pottery – the pottery kilns and their batchArcheologický ústav AV ČR, Brno, v. v. i.34. Social Sciences and Humanities
23-07933SMgr. Jiří Janáč, Ph.D.Technocratic Environmentalism across the Iron Curtain: Czechoslovak experts in the UNECE (1950s-1980s)Ústav pro soudobé dějiny AV ČR, v.v.i.34. Social Sciences and Humanities
23-07934Sdoc. PhDr. Irena Smetáčková, Ph.D.LGBT+ identity as developmental challenge in school environment: individual, group and institutional perspectiveUniverzita Karlova, Pedagogická fakulta34. Social Sciences and Humanities
23-07983Sdoc. Ing. Svatopluk Kapounek, Ph.D.Corporate social behavior and responses to CSR policies, institutions, and economic distressMendelova univerzita v Brně, Provozně ekonomická fakulta34. Social Sciences and Humanities
23-07985Sdoc. PhDr. Roman Chytilek, Ph.D.Same problem, different perception? An experimental research on attributes of political issuesMasarykova univerzita, Fakulta sociálních studií34. Social Sciences and Humanities
23-08052SMgr. Markéta Braun Kohlová, Ph.D.Using the theory of costly signalling to increase social status of frugal consumers and strengthen their pro-environmental consumption patternsUniverzita Karlova, Centrum pro otázky životního prostředí34. Social Sciences and Humanities
23-08311Sprof. RNDr. Luděk Sýkora, Ph.D.Spatial and temporal dynamics of social exclusion and segregationUniverzita Karlova, Přírodovědecká fakulta34. Social Sciences and Humanities
23-04654Sdoc. Ing. Kateřina Valentová, Ph.D.Chemoenzymatic preparation and biological activity of metabolites of food polyphenolsMikrobiologický ústav AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-04690SMgr. Jan Jansa, Ph.D.Arbuscular mycorrhizal symbiosis and soil nitrification - extent and mechanisms of the interactionMikrobiologický ústav AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-04749SRNDr. Vít Latzel, Ph.D.Transgenerational adaptation of a clonal plant in the context of biotic interactionsBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-04866SDocent Michael Wrzaczek, PhDReceptor-like protein kinase-mediated regulation of plasmodesmata and intercellular communication in plantsBiologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-04887SMgr. Jan Bartoš, Ph.D.Identification of genes controlling nondisjunction of the maize B chromosomeÚstav experimentální botaniky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-04891Sdoc. RNDr. Aleš Vaněk, Ph.D.SILVER STABLE ISOTOPE SYSTEMATICS IN ENVIRONMENTS AFFECTED BY MINING AND METALLURGY: METAL DYNAMICS IN SOILSČeská zemědělská univerzita v Praze, Fakulta agrobiologie, potravinových a přírodních zdrojů35. Agricultural and Biological-Environmental Sciences
23-05108SMgr. Tereza Toralová, Ph.D.Maternal protein degradation and its impact on the development quality of mammalian preimplantation embryoÚstav živočišné fyziologie a genetiky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-05132SMgr. Petra Hájková, PhD.New calibration and indicator systems for reconstruction of Holocene climate controlled for local habitat developmentBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-05272SRNDr. Jan Altman, Ph.D.Tropical cyclone activity, drivers, and impact on forest ecosystems at different spatial and temporal scalesBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-05453SMgr. Martina Janoušková, Ph.D.Mycorrhiza as complex insurance of plants for variable conditionsBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-05461SIng. David Püschel, Ph.D.Water holding and translocation via mycorrhizal networksBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-05465SDr Dina in 't ZandtSoil microbiota and soil resources as drivers of self-limitation and stability in grasslandsBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-05564Sprof. RNDr. Viktor Žárský, CSc.FASS/TON2 functions in moss cell morphogenesis and phylogenetic insights into the TTP complex evolutionÚstav experimentální botaniky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-05654SProf. RNDr. Jan Lepš, CSc.Drivers of competition asymmetry in communities of perennial species: ubiquitous but untestedJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-05733SRNDr. Jesús Servando Hernández OrtsFrom the wheel to the thorn: Evolution and adaptations to parasitism in the SyndermataBiologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-05977SAntonín MacháčDiversity dynamics across scalesUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06004Sprof. RNDr. Ivan Čepička, Ph.D.New approaches to the important symbiosis: Diversity and dynamics of the relationship of anaerobic protists and intracelular methanogenic archeaUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06009Sprof. RNDr. Tomáš Cajthaml, Ph.D.Detection of new hazardous micropollutants in drinking water supply system and in vitro study of the toxicity mechanisms using multi-omics approachesMikrobiologický ústav AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06075Sprof. RNDr. Evžen Stuchlík, CSc.Environmental changes caused by extraterrestrial impacts and volcanism: Evidence from lake sedimentsBiologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06116SDoc. Mgr. et Mgr. Josef Bryja, Ph.D.Phyloregions of sub-Saharan Africa: Small mammals as a suitable model group for unbiased quantification of evolutionary diversity and uniquenessÚstav biologie obratlovců AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06133SMgr. et Mgr. Adam Bajgar, Ph.D.The role of macrophages in emergency lipid mobilizationJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06140SHelene Robert Boisivon, Ph.D.Investigating the developmental function of the BnaTAA1 gene family in Brassica napusMasarykova univerzita, Středoevropský technologický institut35. Agricultural and Biological-Environmental Sciences
23-06203SMgr. Tomáš Pánek, Ph.D.Pushing the frontiers of plastid biology research by studying secondarily non-photosynthetic protistsUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06379SRNDr. Eva Kaštovská, Ph.D.Performance of mountain ecosystems along elevation gradients under changing environmental conditionsJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06426SProf. Ing. Otomar Linhart, DrSc.DNA methylation in heterogeneous populations of fish spermatozoa after their aging in vitroJihočeská univerzita v Českých Budějovicích, Fakulta rybářství a ochrany vod35. Agricultural and Biological-Environmental Sciences
23-06429Sdoc. Ing. Jiří Bárta, Ph.D.SoWaFUN - Fungal ecology at the soil-water interfaceJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06455SRNDr. Petr Nguyen, Ph.D.Mechanistic basis and evolution of meiotic idiosyncrasies in LepidopteraJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06457SRNDr. Pavel Hyršl, Ph.D.Identification and functional characterization of bioactive molecules produced by entomopathogenic nematodesMasarykova univerzita, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06507SMgr. Petr Dvořák, Ph.D.Factors driving the global diversification of cosmopolitan cyanobacterium MicrocoleusUniverzita Palackého v Olomouci, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06518Sprof. Ing. Vladimír Košťál, CSc.Diversity and physiological roles of small cryoprotective molecules in drosophilid flies: focusing on mitochondrial membranes.Biologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06568SMgr. Lukáš Falteisek, Ph.D.Genome dynamics and maintenance in simple and homogeneous natural prokaryotic communitiesUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06593SProf. RNDr. Ondřej Prášil, Ph.D.Mechanisms and importance of functional heterogeneity in unicellular nitrogen fixing cyanobacteriaMikrobiologický ústav AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06614SMgr. Martin Kopecký, Ph.D.Linking microclimate and forest dynamics: from plant growth responses to long-term vegetation changeBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-06643SMgr. Vratislav Peška, Ph.D.Disposition, distribution, and processing of DNA lesions in the genome of Arabidopsis thaliana plants defective in DNA repair and nucleosome assemblyBiofyzikální ústav AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06660SHervé LesotPhysiological dynamics of odontogenesis in context of surrounding structuresÚstav živočišné fyziologie a genetiky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06726SMgr. Petra Šarhanová, Ph.D.Sex in apomicts – hidden events detected with novel methods.Masarykova univerzita, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06745SIng. David Janík, Ph.D.How traits mediate tree interactions with neighbours, enemies and mutualists: explaining coexistence mechanisms in tropical and temperate forestsVýzkumný ústav Silva Taroucy pro krajinu a okrasné zahradnictví, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06757SIng. Petr Sedláček, Ph.D.Self-entrapment of Plant Growth Promoting Rhizobacteria by gelation of their exopolysaccharides – towards the next-generation bioinoculantsVysoké učení technické v Brně, Fakulta chemická35. Agricultural and Biological-Environmental Sciences
23-06776SIng. Zuzana Vaňková, Ph.D.Stable Mn oxide-biochar composites – a smart solution for complex soil remediationČeská zemědělská univerzita v Praze, Fakulta životního prostředí35. Agricultural and Biological-Environmental Sciences
23-06806SMarkus HaberPhage host hunt: finding hosts for freshwater phagesBiologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-06840Sprof. Mgr. Martin Lysák, Ph.D., DSc.Evolutionary new centromeres in plantsMasarykova univerzita, Středoevropský technologický institut35. Agricultural and Biological-Environmental Sciences
23-06881Sdoc. Mgr. Pavel Škaloud, Ph.D.Understanding the genetic basis of protist speciationUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06928SMartin DančákDiscovering new species – don’t we really care? The genus Thismia (Thismiaceae) in Borneo and SumatraUniverzita Palackého v Olomouci, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06931SMgr. Jiří Grúz, Ph.D.Phenylsufates in plants and foods: Occurrence, environmental factors and health riskUniverzita Palackého v Olomouci, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06941SIng. Barbora Branská, Ph.D.Inhibitors from bio-waste processing: challenge or opportunity for biotechnological production of chemicals by clostridia?Vysoká škola chemicko-technologická v Praze, Fakulta potravinářské a biochemické technologie35. Agricultural and Biological-Environmental Sciences
23-07000Sprof. RNDr. David Honys, Ph.D.Exploring the regulatory roles of a newly discovered subgroup of bZIP transcription factors in plant developmentÚstav experimentální botaniky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07026SMgr. Miroslav Kolařík, PhD.Unraveling the relationship between ambrosia gall midges and their symbionts: neglected model of fungus farming evolutionMikrobiologický ústav AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07087SJules SegrestinEffects of plant diversity loss on ecosystem carbon cycling in a changing worldJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07103Sprof. Mgr. Jiří Reif, Ph.D.Towards the understanding of processes responsible for farmland biodiversity loss: insights from Central European birdsUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07185SMgr. Markéta Ondračková, Ph.D.Impact of non-native fish species on native parasite diversity in freshwater ecosystemsÚstav biologie obratlovců AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07210SMUDr. Daniel Elleder, PhDVirus sensing and interferon signaling in avian cellsÚstav molekulární genetiky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07216SMgr. Jakub Kreisinger, Ph.D.Interplay between genetics, ecology and symbionts in two adaptive radiations of New Guinean rodentsUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07274Sdoc. Ing. Vladimír Žlábek, Ph.D.Bioaccumulation dynamics of emerging contaminants in aquatic invertebrates using marbled crayfishJihočeská univerzita v Českých Budějovicích, Fakulta rybářství a ochrany vod35. Agricultural and Biological-Environmental Sciences
23-07278SDr. Ivan JaricHarnessing iEcology and culturomics to advance invasion scienceBiologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07287SRNDr. Radka Reifová, Ph.D.The causes and evolutionary consequences of programmed DNA elimination in songbirdsUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07303Sdoc. Mgr. Stanislav Korenko, Ph.D.Darwin wasps as a model of the parasitoid-host coevolution – an integrative approachČeská zemědělská univerzita v Praze, Fakulta agrobiologie, potravinových a přírodních zdrojů35. Agricultural and Biological-Environmental Sciences
23-07331SRNDr. Václav Gvoždík, Ph.D.Genetic networks in the Congolian forests: Unexplored biodiversity archive, herpetological aspectÚstav biologie obratlovců AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07347SMichail Rovatsos, Ph.D.Drivers of differentiation of sex chromosomes: challenging the classical modelsUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07363SMgr. Ondřej Novák, Ph.D.Alternative splicing fine-tunes cytokinin perception in plantaÚstav experimentální botaniky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07376Sprof. RNDr. Břetislav Brzobohatý, CSc.Modulation of the heat stress response by the cytokinin signaling pathway in ArabidopsisMendelova univerzita v Brně, Agronomická fakulta35. Agricultural and Biological-Environmental Sciences
23-07403Sprof. Mgr. Bohumil Mandák, Ph.D.Worldwide phylogeography and history of the globally invasive weed species Chenopodium album.Česká zemědělská univerzita v Praze, Fakulta životního prostředí35. Agricultural and Biological-Environmental Sciences
23-07533SMgr. Lukáš Čížek, Ph.D.Temperate lowland woodlands in transition: How succession, climate change, exotic organisms, and management affect different trophic levels?Biologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07583SMgr. Filip Oulehle, Ph.D.Does tree transpiration drive forest calcium biogeochemistry? Or the other way round?Česká geologická služba35. Agricultural and Biological-Environmental Sciences
23-07658Sprof. Mgr. Lukáš Kratochvíl, Ph.D.Environmental sex determination in amniote vertebrates: a stress‐related mechanism?Univerzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07665SMgr. Marie Altmanová, Ph.D.Is hybridization the only way to asexuality in vertebrates?Ústav živočišné fyziologie a genetiky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07716SIng. Jan Douda, Ph.D.Linking performance trade-off with modern coexistence theory and functional trait approachČeská zemědělská univerzita v Praze, Fakulta životního prostředí35. Agricultural and Biological-Environmental Sciences
23-07733SIng. Přemysl Pejchar, Ph.DAll roads lead to ROS: spatio-temporal regulation of pollen NADPH oxidasesÚstav experimentální botaniky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07744SDr. Győző Garab, Dr.Sc.Identification and characterization of structural entities associated with different lipid phases of plant thylakoid membranesOstravská univerzita, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07776SProf. RNDr. Vojtěch Novotný, CSc.Rainforest succession trajectories along an elevation gradient in times of climate change: a community-transplantation experiment in New GuineaBiologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07811SProf. Ing. Jiřina Száková, CSc.Interaction of parasites and metal(loids) in small terrestrial mammalsČeská zemědělská univerzita v Praze, Fakulta agrobiologie, potravinových a přírodních zdrojů35. Agricultural and Biological-Environmental Sciences
23-07813SRNDr. Jan Petrášek, Ph.D.Revealing the nature of auxin regulation of cell division and expansionÚstav experimentální botaniky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07916SIng. Anna Jirošová, Ph.D.Identification and RNAi silencing of aggregation pheromone production genes in the spruce-killing bark beetles (Ips typographus)Česká zemědělská univerzita v Praze, Fakulta lesnická a dřevařská35. Agricultural and Biological-Environmental Sciences
23-07970SMgr, Karel Říha, Ph.D.Function and dynamics of P-bodies in plant meiosisMasarykova univerzita, Středoevropský technologický institut35. Agricultural and Biological-Environmental Sciences
23-08067SMgr. Kamil Růžička, Dr. rer. nat.Modulating ABA signaling pathways by alternative splicing of ABI2Ústav experimentální botaniky AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences

Announcement of the Results of the Standard Grant Project 2023 Public Call for Proposals

 

POSTDOC INDIVIDUAL FELLOWSHIP

For the second time, the Czech Science Foundation has announced the POSTDOC INDIVIDUAL FELLOWSHIP (PIF) scheme in two modes: OUTGOING and INCOMING. The outgoing mode will allow early-career scientists to participate in a two-year fellowship abroad, where they will gain valuable experience at the early stages of their careers. In the third year, they will capitalize on this experience at a Czech institution. The second mode of the scheme (PIF INCOMING) will enable outstanding early-career scientists from abroad to work at a research institute in the Czech Republic. This tender is also benefiting young Czech scientists abroad who plan to return to the Czech Republic after their postdoctoral experience in another country. A total of 24 young scientists, who obtained their PhD’s no more than four years ago, have been awarded these three-year Fellowship grants, starting in January.

PIF OUTGOING Projects Funded 2023 onwards

Registration No.ApplicantTitleOrganizationNumber of yearsDiscipline committee
23-04903OIng. Martin Ladecký, Ph.D.Reduced-order topology optimisation of high-resolution microstructures with internal contactČeské vysoké učení technické v Praze, Fakulta stavební41. Technical Sciences
23-06074OIng. Ján Mucha, Ph.D.Research of advanced methods of graphomotor disabilities analysis based on fractional calculusVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií41. Technical Sciences
23-05760OMartin PižlRedox and photochemical properties of polypyridyl-based biosensorsVysoká škola chemicko-technologická v Praze, Fakulta chemické technologie32. Physical Sciences
23-06015OMgr. Lukáš Lachman, PhD.Photonic and Atomic Fock State CorrelationsUniverzita Palackého v Olomouci, Přírodovědecká fakulta42. Physical Sciences
23-06344ORNDr. Marek Tuhý, Ph.D.Wildfire-driven metal(loid)s fluxes in mining areas: insights from pilot-scale simulations and in-situ observationsUniverzita Karlova, Přírodovědecká fakulta42. Physical Sciences
23-06384OJán ŠubjakUnveiling the population of close-in exoplanets and brown dwarf companions to starsAstronomický ústav AV ČR, v.v.i.32. Physical Sciences
23-06810ORNDr. Petr Doležal, Ph.D.Investigation of magneto-elastic interaction in quantum spin liquid candidate materialsUniverzita Karlova, Matematicko-fyzikální fakulta42. Physical Sciences
23-07610OMarie ŠvecováCopper-based enhancing substrates for advanced vibrational spectroscopiesVysoká škola chemicko-technologická v Praze, Fakulta chemicko-inženýrská32. Physical Sciences
23-06639OIvone Cristina Igreja e Sa, M.Sc.The role of endoglin in immune cell hepatic infiltration during nonalcoholic steatohepatitisUniverzita Karlova, Farmaceutická fakulta v Hradci Králové43. Medical and Biological Sciences
23-05412OMgr. Martin Lešák, Ph.D.Art, Stational Liturgy, and Communities: Conceiving Monumental Mosaic Decorations in Late Antique Rome (5th–6th Centuries)Masarykova univerzita, Filozofická fakulta44. Social Sciences and Humanities
23-05310ORNDr. Ing. Tomáš Figura, Ph.D.Thief hunt: In search for plants stealing carbon on fungiBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-05469OMgr. Veronika KonečnáRepeated adaptation in wild carnations: the role of shared genetic variation and novel mutations in convergent selection signatures in the genomeBotanický ústav AV ČR, v. v. i.35. Agricultural and Biological-Environmental Sciences
23-05546OMgr. Dora ČertnerováShaping the genome: How environmental factors affect the DNA content evolution in populations of planktonic algae?Univerzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-06710OMgr. Michal Daněk, PhDRole of HIR proteins in effector-triggered immunity in Arabidopsis thalianaÚstav experimentální botaniky AV ČR, v.v.i.45. Agricultural and Biological-Environmental Sciences
23-07045OMgr. Anna Mrázová, Ph.D.Tree defence strategies: why and how does the strength of bottom-up control vary along latitudinal gradient?Biologické centrum AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences
23-07434OMgr. Vojtěch Tláskal, Ph.D.TIMPAOMP project - The IMPortance of Anaerobic Oxidation of Methane in PeatlandsBiologické centrum AV ČR, v.v.i.45. Agricultural and Biological-Environmental Sciences
23-07638OMgr. Martina KarasováThe regulation of xenobiotics metabolism via mechanotransduction: a novel role for the aryl hydrocarbon receptorBiofyzikální ústav AV ČR, v.v.i.35. Agricultural and Biological-Environmental Sciences

Announcement of the Results of the POSTDOC INDIVIDUAL FELLOWSHIP OUTGOING 2023 Public Call for Proposals

 

PIF OUTGOING Projects Funded 2023 onwards

Registration No.ApplicantTitleOrganizationNumber of yearsDiscipline committee
23-06386IMgr. Ondřej Mottl, PhD.BIODYNAMICS: Spatio-temporal dynamics of biotic interactionsUniverzita Karlova, Centrum pro teoretická studia45. Agricultural and Biological-Environmental Sciences
23-06513IMgr. Michaela Walterová, Ph.D.Tidal sounding of terrestrial (exo)planets and binary asteroidsUniverzita Karlova, Matematicko-fyzikální fakulta42. Physical Sciences
23-07242IJan Kotál, Ph.D.Functional characterization of cytokine binding molecules from tick salivaJihočeská univerzita v Českých Budějovicích, Přírodovědecká fakulta43. Medical and Biological Sciences
23-07275IJörn Frederik GerchenPopulation genomic evidence of inter-ploidy introgression and its adaptive significance in natural populationsUniverzita Karlova, Přírodovědecká fakulta35. Agricultural and Biological-Environmental Sciences
23-07330IDr. Goncalo OliveiraThe source of neurological pathology in PNKP-mutated diseaseÚstav molekulární genetiky AV ČR, v.v.i.33. Medical and Biological Sciences
23-07751IMichaela AppeltovaEmbodied Socialism: Gender, Bodies, and the Cold War in Czechoslovakia 1965-1989Masarykův ústav a Archiv AV ČR, v.v.i.34. Social Sciences and Humanities
23-07924IMSc. Mariia Zhadko, Ph.D.Advanced nanostructured metal coatings with superior mechanical properties and high thermal stabilityZápadočeská univerzita v Plzni, Fakulta aplikovaných věd31. Technical Sciences

Announcement of the Results of the POSTDOC INDIVIDUAL FELLOWSHIP INCOMING 2023 Public Call for Proposals

 

The three-stage evaluation process, which all Standard and POSTDOC INDIVIDUAL FELLOWSHIP project proposals go through, involves over 400 experts from each scientific discipline, and dozens of other international reviewers.

Last month, the winning JUNIOR STAR and EXPRO projects were announced. The JUNIOR STAR scheme is targeted at outstanding early-career scientists to enable them to form a scientific team, and pursue their own research topics. The EXPRO grants, on the other hand, are targeted mainly at experienced scientists to provide them with exceptional support. Both types of projects have a five-year duration, and a total of 33 projects will now be funded from next year onwards.

International projects to be funded are announced in consultation with the co-financing agency in the respective other country in the course of the calendar year.

 

SOUVISEJÍCÍ ČLÁNKY

Nearly CZK 1 bn Earmarked for Highly Selective EXPRO and JUNIOR STAR Projects

The Czech Science Foundation (GACR) will fund 10 new EXPRO projects and 23 JUNIOR STAR projects starting next year. These prestigious schemes both aim to promote scientific excellence through superior conditions – EXPRO is designed for seasoned scientists who have a groundbreaking idea, whereas JUNIOR STAR will allow outstanding scientists in their early careers to pursue their own research topics. The five-year projects will receive a total of almost one billion crowns.

“Only the best of the best projects receive funding within EXPRO and JUNIOR STAR, reviewed and recommended by international evaluation panels. Their investigators will enjoy better terms of funding during the five-year project period,” says Petr Baldrian, GACR President. “It is also important what these projects are supposed to bring – EXPRO is expected to deliver a breakthrough in a given scientific field, and JUNIOR STAR fosters the rise of a new, independent scientific generation.” Projects will, for example, focus on the development of new detector systems for particle identification, contribute to more efficient plant breeding through a more detailed understanding of evolutionary forces,  improve the regulatory framework involving artificial intelligence, explore ways to reduce environmental burdens, and design more effective cancer therapies.

The evaluation process involves foreign scientists only. It takes place in two phases – each project that receives funding is first reviewed by six subject-matter experts, and it is then discussed in detail at a meeting of the Discipline Committee.

EXPRO

The aim of the EXPRO grants is to facilitate the development of excellent research, to set standards for excellent science, and to help overcome the barriers inhibiting the success of project proposals submitted to the highly prestigious European ERC grant programme. One of the obligations of the investigators is to apply for an ERC grant. The cost of EXPRO projects, which are mainly designed for seasoned researchers, can reach up to CZK 50 million over five years. The EXPRO grant calls will now be launched in even-numbered years only.

In this year’s tender, out of the ten winning projects, three will be carried out at the Masaryk University in Brno, two each at institutes of the Czech Academy of Sciences, the Czech Technical University in Prague, and the Charles University. One grant has also been awarded to scientists from the Palacký University in Olomouc. Over CZK 450 million will be allocated to these projects.

EXPRO Projects to be Funded 2023 onwards

Reg. numberApplicantProject NameResearch OrganizationDiscipline Committee
23-04754XMgr. et Mgr. Dalibor Blažek, Ph.D.Identification and characterization of a new pathway regulating pre-mRNA splicingMasarykova univerzita, Středoevropský technologický institutEX4
23-04949Xdoc. RNDr. Pavel Valtr, Dr.Fundamental questions of discrete geometryUniverzita Karlova, Matematicko-fyzikální fakultaEX1
23-05692XMgr. Eva Šlesingerová, Ph.D.Robots, Computing the Human, and Autism/Cultural Imaginations of Autism Diagnosis and Emotion AIMasarykova univerzita, Fakulta sociálních studiíEX7
23-06479Xprof. RNDr. Julius Lukeš, CSc.What do the most abundant oceanic protistan proteins actually do?Biologické centrum AV ČR, v.v.i.EX5
23-07085XMgr. Jiří Dědeček, CSc., DSc.Splitting of molecular nitrogenÚstav fyzikální chemie J. Heyrovského AV ČR, v.v.i.EX3
23-07580XJan Vitek, PhdRigorous Engineering of Data Analysis Pipelines (RiGiD)České vysoké učení technické v Praze, Fakulta informačních technologiíEX8
23-07969XMgr, Karel Říha, Ph.D.Biomolecular condensates in plant germline differentiationMasarykova univerzita, Středoevropský technologický institutEX5
23-07973XDr. rer. nat. Torsten SattlerA Unified 3D Map RepresentationČeské vysoké učení technické v Praze, Český institut informatiky, robotiky a kybernetikyEX8
23-07984XJan Weinzettel, Ph.D.PATHWAYS TOWARDS ENVIRONMENTAL SUSTAINABILITYUniverzita Karlova, Centrum pro otázky životního prostředíEX6
23-08019XProf.Dr. Patrik SchmukiSingle-Atom-based 2D-PhotocatalystsUniverzita Palackého v Olomouci, Český institut výzkumu a pokročilých technologiíEX2

JUNIOR STAR

The JUNIOR STAR grants are designed for excellent early-career scientists who completed their Ph.D. no more than 8 years ago, have already published in prestigious international journals, and have had significant international experience. The five-year projects with up to CZK 25 million in funding will give them the opportunity to become independent scientists and possibly to start their own research group to bring new research topics to the world of Czech science.

Starting next year, a total of 23 JUNIOR STAR projects will receive new funding, most of them at the Charles University (5 projects), the Czech Technical University in Prague (4 projects), the University of Chemistry and Technology in Prague (4 projects), and institutes of the Czech Academy of Sciences (3 projects). More than half a billion Czech crowns is earmarked for these projects over the next five years.

JUNIOR STAR Projects to be Funded 2023 onwards

Reg. numberApplicantProject NameResearch OrganizationDiscipline Committee
23-04740Mdoc. Mgr. Zbyněk Heger, Ph.D.Hybrid biocompatible nanocatalysts for extracellular bioorthogonal activation of prodrugsMendelova univerzita v Brně, Agronomická fakultaEX4
23-04869MDr. rer. nat. Benedikt BergmannParticle identification in high-energy physics experiments and space with advanced detection systemsČeské vysoké učení technické v Praze, Ústav technické a experimentální fyziky ČVUTEX1
23-04921MRNDr. Petr Šácha, Ph.D.Unravelling climate impacts of atmospheric internal gravity waves.Univerzita Karlova, Matematicko-fyzikální fakultaEX1
23-04962MRNDr. Vojtěch Vyklický, Ph.D.NMDA receptor conformational dynamics: from structure to function and pharmacologyFyziologický ústav AV ČR, v.v.i.EX4
23-05027MIng. Jakub Cikhardt, Ph.D.Strong electromagnetic pulses: their generation, characterization and controlČeské vysoké učení technické v Praze, Fakulta elektrotechnickáEX8
23-05107MDr. Erin Claire Carson, Ph.D.Inexact Matrix Computations for the Exascale EraUniverzita Karlova, Matematicko-fyzikální fakultaEX8
23-05119MIng. Andrea Konečná, Ph.D.Shaped beams for a new era of electron microscopy and spectroscopyVysoké učení technické v Brně, Fakulta strojního inženýrstvíEX2
23-05194Mdoc. Ing. Ondřej Jankovský, Ph.D.High-strength and water-resistant MOC composites with secondary fillers: contribution of 2D carbon-based nanomaterials and their combinationsVysoká škola chemicko-technologická v Praze, Fakulta chemické technologieEX8
23-05227Mdoc. PhDr. Zuzana Iršová Havránková, Ph.D.Spurious Precision in Meta-Analysis of Social Science Research (METASPUR)Univerzita Karlova, Fakulta sociálních vědEX6
23-05336MMgr. et Mgr. Pavla Perlíková, Ph.D.Development of actin polymerization inhibitors as potential migrastaticsVysoká škola chemicko-technologická v Praze, Fakulta chemické technologieEX3
23-05476MIng. Ctirad Červinka, Ph. D.Making ab initio modelling possible for disordered molecular semi-conductive materialsVysoká škola chemicko-technologická v Praze, Fakulta chemicko-inženýrskáEX3
23-06162MIng. Robert Pěnička, Ph.D.TOPFLIGHT: Trajectory and Mission Planning for Agile Flight of Aerial Robots in Cluttered EnvironmentsČeské vysoké učení technické v Praze, Fakulta elektrotechnickáEX8
23-06540MElías Fuentes GuillénNormalisation and Emergence: Rethinking the Dynamics of Mathematics The case of Prague in the First Half of the 19th CenturyFilosofický ústav AV ČR, v.v.i.EX7
23-06781MBruno de la Torre, Ph.D.Atomic-scale control and visualization of charge delocalization in light-harvesting molecular nanomodelsUniverzita Palackého v Olomouci, Český institut výzkumu a pokročilých technologiíEX2
23-06815MDr. Jan VolecExtremal and probabilistic combinatoricsČeské vysoké učení technické v Praze, Fakulta jaderná a fyzikálně inženýrskáEX1
23-06977MPeter FabianAnalysis of the craniofacial skeletal stem cell nicheMasarykova univerzita, Přírodovědecká fakultaEX5
23-07108MMgr. Ondřej Srba, Ph.D.Changing Adaptive Strategies of Mobile Pastoralists in Mongolia: Dynamics in Community Histories and Movement Patterns Documented Through Oral SourcesMasarykova univerzita, Filozofická fakultaEX7
23-07204MFilip KolářMechanisms driving convergent genome evolution in natural populationsUniverzita Karlova, Přírodovědecká fakultaEX5
23-07283MMgr. Aleš Kudrnáč, Ph.D.The dynamics of adolescents‘ attitudes toward outgroupsSociologický ústav AV ČR, v.v.i.EX6
23-07419MSven Hoeppner, M.Sc., LL.M., Ph.D.Human-Machine Transactions: Behavioral Micro-foundations and Legal ImplicationsUniverzita Karlova, Právnická fakultaEX6
23-07692MRNDr. Vojtěch Kubelka, Ph.D.Animal migrations in a changing world – Movements for reproduction to higher latitudes: still advantageous strategy or maladaptive behaviour? Jihočeská univerzita v Českých Budějovicích, Přírodovědecká fakultaEX5
23-08010MAleš BučekTrajectories of genome evolution in convergent organismsČeská zemědělská univerzita v Praze, Fakulta tropického zemědělstvíEX5
23-08083MIng. Martin Veselý, Ph.D.Synthesis and Property Tuning of Layered Low-Dimensional Materials Beyond Graphene – Utilization in Fundamental Research of Heterogeneous CatalystsVysoká škola chemicko-technologická v Praze, Fakulta chemické technologieEX3

 

The evaluation of EXPRO and JUNIOR STAR project proposals will be made available to proposers in GRIS in the coming days.

SOUVISEJÍCÍ ČLÁNKY

New Evaluation Panel Members Wanted

Every year, the Czech Science Foundation (GACR) receives over three thousand project proposals from all areas of basic research. Over 400 renowned experts help to select the best ones. As the terms in office of about half of them are coming to an end in March 2023, the GACR is launching a call for nominations for evaluation panels. The system has been simplified by making the application electronic and allowing for self-nominations. The deadline to apply is 15 December 2022.

“Without the honest work of the panel members, the Czech Science Foundation would be unable to operate. They are the experts who thoroughly review all of the project proposals submitted, and compare them against one another. Then they recommend the ones that should be funded,” says the President of the Czech Science Foundation, Assoc. Prof. Petr Baldrian. “In order to be able to select as many outstanding experts as possible for our panels, this year we have decided to allow what we call self-nominations – anyone who meets the basic criteria can apply. Anyone whose project has ever been selected for funding should contribute to the evaluation of other scientists’ projects to the best of their ability.  Of course, we continue to welcome nominations of experts by scientific institutions.”

There are 39 evaluation panels at the Czech Science Foundation, grouped into 5 discipline committees by the area of science. In total, there are over 400 experts from all fields who evaluate proposals for basic research projects in tenders for Standard Projects, POSTDOC INDIVIDUAL FELLOWSHIPS, and International Projects.

What are the main responsibilities of a panel member?

 What are the minimum requirements?

 What we offer

 

BECOME A MEMBER OF AN EVALUATION PANEL – apply by 15 December 2022

Important note: If you do not receive confirmation of your nomination within one working day, please contact our helpdesk.

 

 

Call for nominations for members of the evaluation panels of the Czech Science Foundation 2022 (*.pdf) – in Czech only

 

SOUVISEJÍCÍ ČLÁNKY

The President of the Czech Science Foundation along with the Minister for Science, Research and Innovation awarded the five best scientific projects

On Thursday, 29 September, five scientists from various fields of basic research received the President’s Award of the Czech Science Foundation (GA CR) for outstanding achievements. This was the 19th award ceremony in history – for the first time it was presented by Petr Baldrian, appointed President of GACR last year, together with the Minister for Science, Research and Innovation Helena Langšádlová.

The award-winning research projects have provided important insights and methods that make it possible, for example, to identify and sharpen blurry objects in a video, determine the quality of soil based on satellite data, or use machine learning to determine which texts by important authors did not actually come from their pens. The award-winning scientists have also explored how genes are switched on and off in the cell, potentially leading to serious diseases, as well as what influences the rate of ageing.

“The quality of the projects funded – and therefore that of Czech science – has grown year after year. The award-winning researchers deserve our recognition all the more – the award-winning projects have been selected from dozens of scientific projects funded by the Czech Science Foundation, all of which are among the best of the best in the Czech scientific research and even in the world,” said Petr Baldrian, President of the Czech Science Foundation. “It is also gratifying that many of the projects have a potential way forward, towards applied use or understanding of the basic principles of nature and society.”

The President’s Award has been presented regularly since 2003 in recognition of outstanding results achieved in grant projects completed in the previous calendar year. The laureates are selected on the recommendation of several hundred scientists who evaluate projects funded by GACR. Each laureate receives a financial award of CZK 100,000. Prizes are awarded in five areas of basic research: technical sciences; life sciences, medical and biological sciences; social sciences and humanities; and agricultural and bio-environmental sciences.

List of laureates and award-winning projects

Technical Sciences

assoc. prof. Ing. Filip Šroubek, Ph.D., DSc., Institute of Information Theory and Automation, Czech Academy of Sciences

Solving Inverse Problems for the Analysis of Fast Moving Objects

The award-winning project has developed a method that allows to significantly improve the image quality, despite the limited technical possibilities of recording. The method relies on the fact that more information can be extracted from a blurred video than from a single sharp image – such as the 3D trajectory and angular velocity of an object. This makes it possible to reconstruct the shape, appearance, and motion of a fast-moving object. Additional image sharpening will also find applications in scientific experiments, defence, healthcare and other fields.

Physical Sciences

M.Sc. Asa Gholizadeh, Ph.D., Czech University of Life Sciences, Prague, Faculty of          Agrobiology, Food and Natural Resources

Soil Contamination Assessment Using Hyperspectral Orbital Data

This junior project provided a breakthrough method for identifying contaminated soil using freely available satellite data. The newly developed method also uses machine learning algorithms to process the data – making it possible to extract the information of soil contamination from satellite images over large areas quickly, cheaply, and environmentally friendly. The method will allow new and accurate algorithms to be implemented in future space-based sensors to monitor global soil contamination over time and space.

Medical and Biological Sciences:

assoc. prof. Ing. Václav Veverka, Ph.D., Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences

The Evolutionary and Functional Relationship between LEDGF/p75 and Pdp3

As part of the project, the researchers looked at how selected types of protein stretches, previously identified in studies of leukaemia and HIV infection, can affect RNA chain elongation. They have gradually untangled a wide network of interacting cellular partners that influence this process. They were thus able to uncover a previously neglected role for unstructured protein domains in ensuring this cooperation. This discovery may contribute to a better understanding of cancer, viral or neurodegenerative diseases, and other conditions that are caused by disrupted gene expression.

Social Sciences and Humanities:

Mgr. Petr Plecháč, Ph.D. & Ph.D., Institute of Czech Literature, Czech Academy of Sciences

Stylometric Analysis of Poetic Texts

The project focused on identifying the authors of poetic texts using machine learning. In addition to commonly used textual features, such as word and phrase frequency data, the researchers also focused on formal features of the verse (verse rhythm, rhyme), which they were able to prove to significantly increase the reliability of the results. Using machine learning, for example, the team was able to determine which passages Henry VIII and Two Noble Kinsmen, both versed plays, were from the pen of William Shakespeare, and which were from his co-author John Fletcher.

Agricultural and Biological-Environmental Sciences:

prof. RNDr. Martin Reichard, Ph.D., Institute of Vertebrate Biology, Czech Academy of Sciences

Sources of Intrapopulation Heterogeneity in Ageing

Ageing is biologically a process of deterioration in the optimal functioning of an organism, and an increase in the risk of failure of some essential function. This project has uncovered the causes of the different rates of ageing in male and female African turquoise rockfish in nature and in the laboratory and described how environmental conditions, embryonic development and growth rate can influence the ageing process. Understanding the sources of differences in ageing rates is also important for addressing current issues in the ageing human population.

Czech Science Foundation

The Czech Science Foundation (GACR) is the only institution in the Czech Republic that provides targeted aid from public funds to basic research projects only. The objectives of GACR are to fund basic research projects carried out by scholars and their teams, both seasoned scientists and young ones in their early careers, to create suitable and attractive conditions for scientists, and to promote and expand international scientific cooperation. GACR launched its activities in 1993.

SOUVISEJÍCÍ ČLÁNKY

JUNIOR STAR projects

JUNIOR STAR grants are intended for excellent scientists in their early careers within 8 years of receiving their PhDs who have published in prestigious international journals before, and have had substantial experience abroad. The 5-year project allows them to receive up to CZK 25 million and gives them an opportunity to attain scientific independence or even start their own research team, which can bring new areas of research into Czech science. Only a fraction of submitted projects receive funding.

JUNIOR STAR 2025

Abstract

“The project aims to develop a quantitative imaging technique for the human cholinergic system, critical for cognitive functions, and vulnerable in neurodegenerative diseases. By employing advanced MRI methods, including advanced diffusion and functional MRI, we plan to quantitatively assess its components, such as nuclei, projections, and cortical targets. Our novel approach involves longitudinal studies to capture the system’s dynamics over time, contrasting the static snapshots of cross-sectional research. Cholinergic projections from the basal forebrain to the cortex are notably impaired in Alzheimer’s disease and dementia with Lewy bodies, leading to significant deficits due to neuron degeneration and the presence Lewy bodies, respectively. The importance of the cholinergic system in these conditions is underscored by the effectiveness of acetylcholine-modifying drugs as a common treatment approach. Therefore, precise imaging of cholinergic pathways and cortical regions is critical for improving diagnosis, monitoring disease progression, and guiding therapeutic interventions.”

Project Aims

“The project aims to develop a cutting-edge multimodal structural and functional technique for in vivo quantitative imaging of the human cholinergic system and to investigate its pathophysiology in a longitudinal manner in both normal and abnormal aging.”

Abstract

“The evolution of artificial intelligence, spurred by advancements in neuromorphic computing and large language models, demands increasingly energy-efficient computing systems. Photonic neural networks (PNNs) have emerged as a promising avenue towards achieving this goal. Furthermore, they also offer the advantage of high-speed and parallel processing by light. This project explores integration of a volatile phase-change material, vanadium dioxide (VO2), into PNNs to address the limitations of their current forms. By capitalizing on the unique properties of VO2, such as ultrafast phase changes at low energy threshold, we aim to develop more compact and efficient PNN components, study their functions in contemporary and advanced neuromorphic topologies, and finally experimentally demonstrate neuromorphic computing tasks with these innovative devices. Through a multidisciplinary approach combining expertise in nanostructure fabrication, optical simulations, and circuit design, we seek to unlock the untapped potential of VO2 in novel PNNs for faster and more energy-efficient computing.”

Project Aims

“Explore volatile phase-change material (VO2) in photonic neural networks (PNNs): 1) Study VO2’s activation for neuromorphic computing. 2) Implement VO2 nanostructures into neuromorphic elements. 3) Integrate VO2 into waveguides for PNN prototypes. 4) Utilize VO2 in advanced neuromorphic concepts.”

Abstract

“Acute ischemic stroke is the second leading cause of death. It is caused by fibrin clots blocking blood flow to the brain. Thrombolytics are practical and affordable, clot-dissolving drugs, but show many limitations. Alteplase, which is the only FDA-approved drug, causes bleeding and has a narrow therapeutic window. Staphylokinase is a promising alternative due to its high specificity for fibrin and lower production costs, but it suffers from high immunogenicity and low affinity to plasmin, which reduces its effectiveness. This project proposes to use protein engineering methods to develop the next-generation thrombolytics to overcome these limitations. We will modify Alteplase to reduce side effects and improve fibrin specificity and penetration into the clot. For Staphylokinase, we will focus on increasing its affinity for plasmin, while preserving its benefits. By combining rational design, computational methods, and experimental characterization, this project has the potential to develop, more efficient, safer, and more affordable thrombolytic drugs for the treatment of stroke.”

Project Aims

“This project is focused on 3 main aims: 1) the development of methods for the analysis and engineering of Alteplase, 2) the development of methods for the analysis and engineering of Staphylokinase, and 3) the experimental validation of designs proposed in aims 1 and 2.”

Abstract

“Deactivation of zeolite-based catalysts due to the deposition of high-molecular-weight carbon species (coking) poses a significant challenge in methanol-to-hydrocarbons (MTH) conversion processes. These processes are crucial for producing essential chemical intermediates from non-petroleum resources but often require costly regeneration. The design of superior MTH catalysts with minimized coking propensity hinges on a fundamental understanding of micropore fouling by coke. This project aims to address this gap by leveraging neutron powder diffraction (NPD) to understand coke formation within micropores during MTH reactions. This innovative approach holds great potential for pinpointing the structure and location of coke species inside micropores. By investigating various zeolite structures, the project seeks to unravel how pore geometry and the distribution of active sites influence coke evolution and catalyst deactivation. This research will elucidate the impact of coke species on catalyst performance, providing crucial insights for the design of more durable MTH catalysts.”

Project Aims

“The project aims to achieve a fundamental understanding of the evolution of coke, including its structure and location within the micropores of zeolite catalysts, with respect to the framework topology and geometry, which is a key for development of improved methanol to hydrocarbon catalysts.”

Abstract

“There still exist knowledge gaps regarding the perspective of resorbable magnesium implants that dissolve completely in the body. Although the instrumentation capabilities for materials testing are constantly evolving, there is not enough attention paid to mimicking the human body environment. This results in the overuse of experimental animals even for proof of concepts that could be confirmed or refuted in vitro. Furthermore, prominent problems connected with Mg implants are often overlooked, such as static vs. dynamic test conditions, hydrogen generation, corrosion localization, corrosion product redeposition, and the effects of sterilization and storage. The project will use dynamic mechanical analysis (DMA), together with a flow-through bioreactor to elucidate fundamental aspects of in vitro degradation. Moreover, in vitro-in vivo correlation factors and advanced polymer-based and composite protective coatings will be studied to address other pressing issues of these implants while providing a way for surface functionalization, including localized drug elution.”

Project Aims

“(1) Design of functional coatings of Mg-based implants. (2) Determining the barriers affecting in vitro-in vivo correlation factors. (3) Comparison of static and dynamic loading of implants in simulated body media. (4) Studying the effects of storage and sterilization on Mg implants.”

Abstract

“The fundamental research project aims to explore how future mobile aerial robots could utilize their senses to detect and model their surrounding environment. We hypothesize that a significant methodological leap is necessary beyond the incremental improvements of current SLAM (Simultaneous Localization and Mapping) systems. The accuracy-focused SLAMs currently in use are limited by their real-time performance due to their complexity. We propose a biologically-inspired approach for multi-modal semantic feature extraction, which is gradually becoming feasible with advancements in visual object detection and classification. Our objective is to generalize robot navigation in real-world environments without relying on precise motion odometry. To achieve this, we intend to develop novel methods for learning and extracting multimodal landmarks from sensor data. Additionally, we seek to address the fundamental challenge of sharing plans and paths between robots and humans in environments where there is no prior knowledge available about the environment and no notion of global coordinates.”

Project Aims

“1. Developing new methods for learning and extracting multi-modal landmarks from sensor data. 2. Generalizing robot navigation in real-world environments without precise localization and motion odometry. 3. Investigating the way to share plans and paths between robots and human operators.”

Abstract

“Nickel catalysis offers a promising alternative to conventional precious-metal-dependent crosscoupling methods, facilitating the formation of diverse C–C or C–X bonds. However, traditional ligands that have been in use for decades limit the applications and restrict the reaction conditions, the range of organic substrates, or the variety of activation pathways. Our interdisciplinary research explores new ligand effects and catalyst activations. Combining synthesis, molecular spectroscopy, and theoretical calculations, we analyze the impact of sterics, electronics and ligand redox non-innocence on Ni complexes, particularly their photochemical, photophysical, and electrochemical properties. The aim is to reveal structure /function relationships to guide design of advanced Ni catalysts. The goal is to broaden the scope, improve yields and selectivity in traditional cross-coupling catalysis, and at the same time reveal new possibilities for the reactivity of Ni complexes, useful for original applications in the synthesis and production of organic molecules or small-molecules activation.”

Project Aims

“Study of original ligands for Ni catalysis. Comparison of steric and electronic contributions. Use of photochemical and electrochemical activations. Combining experiment and theory to reveal structure/function relationships. A rational approach to optimize reaction conditions and substrate scope.”

Abstract

“This grant proposal addresses the critical need to advance our understanding of host-pathogen interactions, particularly focusing on coronaviruses. Our study seeks to elucidate the plasticity of protein-protein interactions, especially in coronaviruses’ receptor binding domains (RBDs), which play a crucial role in viral entry and infection. To achieve these aims, we propose utilizing in vitro evolution with random mutagenesis to affinity maturate multiple coronaviral RBD domains. Through deep sequencing and comprehensive characterization, we aim to map key residues responsible for high-affinity binding to human receptors and their impact to infectivity. By predicting and understanding the trajectories and mutations of pathogens, we can preemptively prepare for their changes, potentially limiting their evolution and pandemic potential.”

Project Aims

“The aim of the project is to analyze the evolutionary pathways of coronavirus receptor binding domains (RBD, NTD) towards high affinity to human receptors and to analyze mutational barriers through in vitro evolution mimicking viral evolution, analyzing affinity, infectivity, and structural changes.”

Abstract

“PolyHydroxyAlkanoates (PHA) are microbial polyesters produced by many prokaryotes with great potential in replacing current petrochemical plastics. Sadly, only half of the PHA cycle, notably degradation, is described in ample detail, especially from the perspective of bioinformatics. While the database of PHA depolymerases exists, its counterpart summarizing knowledge of PHA synthases is missing. This lack of knowledge hampers the design of novel technologies for sustainable production of advanced PHA materials. In the project, we will design a robust computational pipeline to analyze all currently available prokaryotic genomes to propose a novel classification of PHA synthases. Moreover, we will experimentally characterize tens of microorganisms and microbial consortia producing PHAs and perform several in vitro and in vivo experiments to describe the properties of particular synthases. Also, we will analyze the material properties of polymers synthesized with various synthases. In the end, we will develop a comprehensive database of PHA synthases allowing computational analyses.”

Project Aims

“The aim of the project is to propose a robust computational pipeline for novel classification of PHA synthases and their comprehensive database, considering also the material properties of polymers they synthesize for the selection of bacteria utilizable for industrial production of bioplastics.”

Abstract

“Interpolation is a fundamental metalogical property of broad importance to several fields, including software/hardware verification, databases, mathematics, and philosophy. This project aims to bridge the gap between the two dominant paradigms in the study of interpolation: the proof-theoretic approach and the algebraic approach. By reconciling these methodologies, the project will develop a systematic account of interpolation in varied environments, and, in particular, will produce a flexible and powerful toolkit for investigating interpolation in different logical contexts. Our investigation places a special emphasis on finding broadly applicable techniques for understanding computational aspects of interpolation, such as the decidability of various questions relating to interpolation and complexity of the associated algorithms.”

Project Aims

“(1) Bridge the gap between syntactic and semantic approaches to interpolation. (2) Provide a systematic account interpolation across different logical contexts. (3) Deploy insights from the more cohesive framework to deepen our understanding of interpolation in important case studies.”

Abstract

“Characterization of a quantum state, known as quantum tomography, is one of the most important tasks in emerging nanoscale technologies. These technologies exploit phenomena such as superposition and entanglement to achieve tasks that are not possible classically. Tomography is used, for example, to validate quantum algorithms, find sources of experimental errors, ensure secure communication, and optimize the design of quantum sensors. However, traditional tomography methods, based on classical statistics, struggle with efficiency. We plan to revolutionize this by introducing an adaptive quantum tomography framework based on the recently discovered quantum Bayes’ theorem. This method is very promising in terms of its ease of implementation and applicability to a significantly larger number of qubits. By adopting adaptive measurements, our method aims for quick convergence, outperforming existing techniques and accelerating the deployment of faulttolerant and scalable quantum technologies.”

Project Aims

“Develop a method of quantum tomography that is faster, easier to implement, and applicable to significantly larger systems than existing methods. Establish cutting-edge research of quantum technologies at Charles University and improve its presence in the Czech Republic, according to VaVaI 1.1.1.”

Abstract

“Proportionality and consistency are two primary aspects determining whether a sentence is just. This project aims to evaluate both proportionality and consistency in unprecedented detail. Such evaluation will be enabled by creating generalized behavioural categories based on descriptions of sentenced behaviour in court verdicts using large language models, allowing for going beyond simple legal classification. I will first use them to assess whether the emphasis put on proportionality and consistency by some countries is reflected in their sentencing practices. To investigate proportionality, I will identify what harm dimensions determine the ranking of offenses according to their seriousness and whether the public and courts differ in what dimensions they prefer. To examine consistency, I will describe and evaluate previously unexplored unifying practices of prosecutors and I will experimentally test the effectiveness of evidence-based sentencing orientations, which I will formulate using behavioural categories and identified preferences of proportionality.”

Project Aims

“The project aims to complexly analyze proportionality and consistency at sentencing by employing generalized behavioural categories. Judicial practice in different countries, harm dimensions and effectiveness of measures destined to improve proportionality and consistency will be assessed.”

Abstract

“The explicit illustration of Einstein’s E = mc^2 is the process of converting photon energy into matter, i.e. into electron and positron. Electron-positron pairs are present in astrophysical systems, such as those associated with neutron star and black hole environments. With the advent of multi-petawatt laser facilities, the possibility of creating electron-positron pairs via the multiphoton Breit-Wheeler process in multiple laser pulse collision has attracted a lot of attention motivated by the demand to study the fundamental quantum electrodynamics processes present in extreme astrophysical environments using high intense laser fields. Using supercomputers and exploiting the potential of structured laser pulses we design a laser-based optical system for efficient conversion of light (photons) into matter and antimatter (electron and positron). Based on the numerical model, we propose the laser-based experimental setup for cascade electron-positron pair generation.”

Project Aims

“Using supercomputers and exploiting the potential of structured laser pulses we design an extremely efficient optical trap for electron-positron cascade pair creation allowing to reach orders of magnitude higher number of created positrons compared to so-far considered optical structures.”

Abstract

“The global incidence of autoimmune diseases has surged in recent decades. Understanding the mechanisms safeguarding the mammalian immune system against the development of autoimmunity is crucial for future interventions. We focus on the processes of central immune tolerance that occur in the thymus and are crucial for the formation of a functional and safe T cell repertoire. Central to this are thymic antigen-presenting cells that present self-antigens to developing T cells to eliminate self-reactive clones and prevent autoimmunity. However, how the thymus provide tolerance to inflammation-related antigens remains unknown. Our preliminary data suggest that thymus accommodates a novel population of transitional dendritic cells (tDCs) that have the potential to migrate to the thymus and present peripheral antigens to developing T cells. This project aims to characterize the role of tDCs in thymic T cells tolerance to inflammation-related self-antigens under steady-state conditions and during inflammation and provide insight into their impact on autoimmunity development.”

Project Aims

“The project aims to characterize the origin, development, migration capacity and the role of novel thymic transitional dendritic cells population in T cells tolerance under steady-state conditions and during inflammation.”

Abstract

“Medieval society was ruled by a patriarchal monarchical system that tended to exclude females from power. However, queens and other royal women were powerful agents whose voices were consequential in all sectors of society. Their impact could have taken many forms, ranging from direct governance to social and cultural patronage. This project sets out to explore Bohemian queenship, that is the role and office of royal women in the Late Middle Ages, by concentrating on three aspects: power, resources, and effects. By analysis of primary sources and implementation of the most recent trends in queenship and gender studies, the project will shed light on the fluidity of agency of selected Bohemian royal women in the interaction with masculine power. To evaluate the character of gendered layers of rulership, the project will analyse financial and social resources and the legal and ritual setting, which enabled the female agency. Finally, it will study the traces and imprints of the queenly power left in material and written culture, architecture, and art in Central Europe and beyond”

Project Aims

“This project aims to change the way of studying Bohemian queens, shifting from a biographic and positivistic approach to the systematic analysis of the queenship as a gendered component of late medieval monarchy by examining queenly resources, modalities and impact of their power and agency.”

Abstract

“Additive manufacturing (AM) of metals has revitalized the interest in metallurgy. Even familiar metals like steels exhibit unique behaviors when produced through AM, owing to the inherent heterogeneity of AM materials. While some aspects of heterogeneity can be mitigated, others, like columnar grains and texture, pose persistent challenges. However, AM offers unprecedented control over material properties through precise manipulation of composition and microstructure. This project focuses on complex understanding the micromechanisms of phase transformations, texture evolution, and deformation mechanisms in austenitic steels fabricated via AM techniques. Most importantly, controlled local changes of microstructure and composition during AM will result in materials with locally enhanced mechanical properties. Experimental data will inform the development of the MTEX model, facilitating the design of complex structures. Leveraging expertise gained from neutron and synchrotron diffraction experiments, the project aims to advance the understanding of AM-produced metals.”

Project Aims

“The aim of the project is to understand the micromechanical properties of steels prepared by additive methods and to prepare complex structures with locally modified mechanical properties to improve the overall mechanical properties.”

Abstract

“Plants produce diverse specialized metabolites, crucial for their defence and communication with other organisms. Understanding global drivers of chemical diversity remains fragmented. Prior studies explored different dimensions of chemical diversity in isolation and limited analysis to specific metabolites and environmental stressors. To comprehend overall trends in the astonishing diversity of specialized metabolites, we must assess how various stressors influence different dimensions of their diversity. Abiotic stress at high latitudes likely drives chemical convergence, while herbivore pressure in the tropics may promote chemical divergence among plant species. I’ll employ novel metabolomics methods to show how these processes shape latitudinal clines in metabolite concentration, richness, variation, and structural diversity, influencing global turnover in plant chemical strategies. I aim to link the macroevolution of chemical diversity to its ecological function, uncovering factors driving the exceptional diversity of plant metabolites.”

Project Aims

“I will show how different selection pressures support different dimensions of diversity of specialized metabolites in plants growing in various environments. My project will explain the global turnover in plant chemical strategies and reveal the factors contributing to plant chemical diversity.”

Abstract

“Since the beginning of the Russian invasion of Ukraine in 2022, there has been a significant increase in the number of Ukrainian pupils in Czech schools, with their share reaching 3.7% of all pupils. Ukrainian pupils represent the largest group of foreigners in schools. The research is aimed at exploring the inclusive efforts of Czech schools towards Ukrainian refugee pupils by analyzing the current efforts and needs of key stakeholders in the educational process. The main aim of the research is to provide findings that can contribute to improving the educational conditions for Ukrainian refugee pupils in schools and to support the development of an inclusive learning environment in Czech primary schools. The methodology of the project involves conducting a multiple case study, questionnaire survey with a randomized sample in the South Moravian Region. The research will be conducted using the following methods: focus groups, questionnaire survey, semi-structured interviews, observations, quasi-experiment. The main output of the project will be 5 scientific articles (2 JIMP, 3 JSC).”

Project Aims

“1.characterize the inclusive efforts of Czech schools for Ukrainian students; 2.to analyze the development of inclusive approaches in primary schools over the course of Ukrainian students’ education; 3.identify the needs of students, teachers, and parents for an inclusive environment in Czech school”

Abstract

“The aim of this project is research in the field of ultrafast photon detectors based on singlephoton avalanche diodes and their application in quantum-assisted astrometry. This new technique is based on the interferometric sensing of photon phases of light emitted by two independent astronomical objects at two or more separate telescope stations. Such approach allows construction of synthesised aperture optical telescopes of arbitrary baseline with the achievable angular resolution in the order of 10 microarcseconds during single night observation, thus bringing the performance seen in radio telescope arrays into the optical region. Achieving the successful demonstration, this technology has a great potential to revolutionise astronomical observations. In addition, the developed instrumentation, such as spectrometers with excellent time resolution, will help to further explore the uncharted territory in the field of real-time imaging of chemical and biological reactions, time-of-flight mass spectroscopy or detection and characterization of photons in quantum optics and networks.”

Project Aims

“The main objectives are commissioning of new Heisenberg-Uncertainty Principle limited spectrometer, performing proof-of-concept quantum assisted astrometry measurements, and establishment of group, bridging expertise from experimental physics and astrometry.”

 

JUNIOR STAR 2024

Abstract

One of the most important discoveries in microbiology in the last decade was Candidate Phyla Radiation (CPR) or ‘Ca. Patescibacteria’, a recently described phylum of mostly episymbionts that include up to 26% of bacterial diversity. Although >2400 representative genomes are available, less than a dozen members were cultivated to date, belonging to just two out of 24 CPR classes. Because to their prevalence in the environment, cultivating ‘Ca. Patescibacteria’ is important, but notoriously difficult due to their complex nutrition needs and reliance on other microorganisms, and new strategies and techniques are needed to understand their ecophysiology. In our project, we propose to target both partners with metatranscriptomics and EpicPCR to assess the functional potential and host range of CPRs. Further, we aim to obtain episymbionts – hosts co-cultures by combining reverse metagenomics and high-throughput cultivation. These approaches represent the necessary steps that will advance the understanding of CPRs biology.

Project Aims

The project aims 1) to understand the functional potential of ‘Ca. Patescibacteria’ members in the environment; 2) to assess the host range of these epi- and endo-symbiotic bacteria; and 3) to obtain new enrichment cultures and co-cultures.

Abstract

Our research will study the emerging connections between model theory and structural graph theory. Model theory provides a collection of concepts and tools for analyzing the complexity of infinite structures, and these are mirrored in the analysis of finite structures. For some time, this similarity seemed only analogical, but recent results have shown that the model-theoretic machinery can be finitized, and doing so recovers key definitions from structural graph theory and provides new and unified tools for proving results about them. The main conjecture that serves to focus our efforts is algorithmic in nature: it identifies a certain model-theoretic property as characterizing the graph classes on which a wide swath of algorithmic problems (namely, those expressible in first-order logic) can be efficiently solved. While most researchers active in the area approach from the combinatorial viewpoint, we plan to use our expertise to take a model-theoretic approach to this problem, and also to see how the combinatorial concepts can feed back into model theory

Project Aims

We plan to develop the interaction between model theory and structural graph theory, and in particular to (try to) solve a conjecture about graph classes that admit efficient algorithms.

Abstract

In this interdisciplinary project, we will develop a research model for studying the relationship between literature and society through a critical discussion of relevant paradigms in literary theory and sociology from their foundation to the present. The project consists of two parts: First, we will conduct metatheoretical research on how the relationship between literature and society has been studied throughout the history of literary theory and sociology. We will focus on the epistemological and ontological assumptions of the most dominant approaches and investigate how these assumptions determine the treatment of the literary-social link. Second, we will synthesize selected approaches and construct a theoretical hypothesis, which will be empirically tested on five distinct case studies. The goal is to design a model of literary communication that combines micro- and macro-perspectives to study literary production, reception, internal textual structure, and their interconnectedness, thus granting literature and society equal valence in the analysis—epistemological symmetry.

Project Aims

1. Identify and make transparent the asymmetries between the “literary” and the “social” in previous literature-and-society research. 2. Employ this knowledge to design a model of literary communication that grants the “literary” and “social” epistemological symmetry and develop it on case studies.

Abstract

Advances in organic chemistry have enabled life-changing discoveries and fostered key developments in medicinal, agricultural and materials chemistry. However, bridging fundamental knowledge gaps and meeting increasing demands for more safe, practical, and easily scalable organic syntheses while also reducing their step-count, cost, and environmental impact requires developing innovative synthetic methods. The research proposal tackles these challenges by developing conceptually innovate and unprecedented synthetic methods based on two emerging research areas: 1) molecular editing, for predictive and selective manipulation (e.g., migration) of native functional groups, and 2) radical-based C–C/C–N cross-coupling, for bond formation at sp3-hybridized carbon centers. To this end, this research will tap into the potential of transition metal catalysis, electrochemical activation, and radical chemistry approaches. The resulting methods will be then applied to overcome current limitations in the synthesis of bioactive compounds and natural products.

Project Aims

Development of novel catalytic and electrochemical synthetic methods for 1) migration of functional groups in organic compounds, 2) radical-based C–C a C–N cross-coupling reactions. Application of developed methods in the synthesis of bioactive compounds and natural products.

Abstract

Electronic spin in molecules of coordination compounds is promising as the basic logic unit of quantum computers. This technology will transform various aspects of society by enabling faster and more efficient computation, secure communication, and precise sensing. Molecules can be tailored to achieve specific magnetic properties through simple ligand substitution. Among the desired features is quantum entanglement, which interconnects the molecular quantum states for quantum information processing. Molecular crystals are formed through hydrogen bonds or other weak interactions between neighbor molecules, resulting in a structure that gives rise to spin lattices and spin-spin couplings. We will use electron spin resonance (ESR) to explain the crucial role of weak intermolecular interactions in determining the entanglement phenomenon in molecular crystals. A thorough understanding of these interactions is essential to successfully implement molecular crystals in future quantum devices.

Project Aims

Investigate the effect of the weak exchange and the control of quantum entanglement in molecular crystals by screening new coordination compounds and pushing forward the state-ofthe-art in electron spin resonance, envisioning possible applications in quantum devices.

Abstract

In mammalian female foetuses, the oocytes are established as a finite pool. They enter meiosis I before birth and remain arrested until the meiotic resumption during the reproductive period, leading to ovulation. Oocytes of long-lived species can be arrested for decades while maintaining the quality to support embryonic development. To understand the mechanisms of long-term female fertility, we study naked mole rat (NMR) and giant mole rat (GMR), rodents with reproductive span greater than 20 and 15 years, respectively. Decreased oocyte quality in aged mice was linked with transposon (TE) dysregulation and deleterious effect of ovulations. Low genomic content of potentially active TEs and social system comprising ovulating and nonovulating females make NMR and GMR suitable models to study the effect of TEs and ovulatory cycles on oocyte and ovarian quality. By combining the latest genomics and imaging technologies, we will assess the consequences of low TE activity on the oocyte transcriptome and epigenome, and the effect of ovulations on the aging-associated decline of the quality.

Project Aims

We aim to determine the role of transposons and ovulatory cycles on female fertility by studying the effect of low transposable element activity and natural absence of ovulations on oocyte and ovarian quality in mole-rats, long-living rodents with long-term female fertility.

Abstract

ABC-stacked trilayer graphene is known to exhibit a clean tunable energy bandgap by a perpendicular field, an important feature for its future applications in electronics and optoelectronics. However, the major techniques used to prepare ABC graphene struggle with a maximal size of ABC graphene, which is around 100 nm, making any future applications impossible. Therefore, we propose to use ABC-stacked epitaxial graphene on a silicon carbide substrate grown by silicon sublimation, which enables the preparation of homogeneous graphene on a large scale, for the development of tunable electronic and optoelectronic devices. In particular, we aim to develop a detector of terahertz and far-infrared radiation based on ABC-stacked graphene by tailoring the energy bandgap with a perpendicular electric field. The detection performance will be tested at temperatures from cryogenic to room temperature, and compared with conventional liquid-helium-cooled bolometers.

Project Aims

The project’s goal is to fabricate and characterize tunable electronic and optoelectronic components based on ABC-stacked trilayer epitaxial graphene on SiC substrate. We aim to optimize the growth technique and comprehensively study the tunable properties of ABC graphene.

Abstract

Maternal stress, anxiety, and depression during pregnancy have long-lasting consequences for the child, manifesting as emotional and behavioral problems. Still, the mechanisms of this intergenerational transmission are not well understood. The ambition of the current project is to identify the mechanisms underlying the relationships between maternal health during pregnancy and brain structure, function and behavior in the child. We aim to test the mediatory role of inflammation and accelerated aging in these relationships and demonstrate what environmental factors might magnify or protect against the negative impact of maternal illness during pregnancy. This high-risk/high-gain project would provide ground-breaking new insights into the mechanisms of prenatal programming and allow the development of targeted interventions that would reduce the odds of mental illness in the new generations. Our findings will thus contribute to two areas of the national priority Healthy Population: (1) Origin and Development of Diseases and (2) Epidemiology and Prevention of the Most Serious Diseases.

Project Aims

ChiBra project aims to identify the mechanisms underlying the relationships between maternal mental health during pregnancy and child’s brain and behavior. We will test the mediatory role of inflammation and accelerated aging and demonstrate what environmental factors moderate these relationships.

Abstract

Religions permeate the lives of billions and are hypothesised to play an essential role in normative behaviour. Yet, little is known about how religious devotion penetrates cognitive computations during decision-making. I fill this lacuna by proposing a computational model of religious decision-making. In this model, religious belief, forged through religious practice, forms strong priors in the mind. When the mind simulates possible actions during decision-making, religious actions become readily available and likely selected due to their high value. To empirically develop the model, I will determine how religious belief affects the strength of religious priors during normative decision-making in various laboratory and field studies. Moreover, in a large-scale cross-cultural study, I will establish how beliefs and practices of different religious traditions affect cognitive computations during normative decisions. The project will producing one-of-a-kind, comprehensive model of how religions shape the mind, and document the workings of this model across at least 12 articles.

Project Aims

The CREDO project aims to devise and test a computational model that will explain how religious devotion affects normative decision-making. The long-term vision is to provide a formal computational platform offering a deeper understanding of the workings of human mind within cultural complexity.

Abstract

Atropisomers are separable conformational isomers arising from restricted rotation around a single bond which revolutionized drug discovery. The main goal herein is inducing conformational restriction to create new drugs by developing catalytic stereoselective synthesis methods toward difficult-to-access drug-like atropisomers. We will study how conformational changes, from achiral and flexible to chiral and more rigid atropisomeric forms, impact a molecule’s ability to interact with biological receptors. To accomplish this, we will introduce three new catalytic atroposelective methods. 1) We will develop the first atroposelective amidebond formation toward atropisomeric peptidomimetics. (2) We will generate sphere-shaped atropisomers. This rarely investigated area of molecular shape is sought-after in drug discovery. (3) We will develop the first atroposelective decarboxylation of esters. Collectively, the resulting knowledge will shed light on differences between pharmacological properties of achiral and chiral atropisomers, constituting an invaluable insight for drug discovery.

Project Aims

Discovery of new atropisomeric drugs by development of unprecedented catalytic stereoselective synthesis methods toward difficult-to-access drug-like atropisomers.

Abstract In this project we will identify the network of effectors enabling Salmonella to establish a longlasting niche in its host by inhibiting crucial T cell response. The Salmonella pathogenicity island 2-encoded type III secretion system (SPI-2 T3SS) is known to translocate effectors inhibiting migration of dendritic cells, inducing anti-inflammatory conditions, and blocking antigen presentation. However, my preliminary data show that only a subpopulation of intracellular bacteria express effectors involved in subversion of the T cell immunity. This leads to formation of distinct populations of infected antigen-presenting cells that induce different T cell phenotypes. Using the effector network approach, we will identify contribution of individual effectors to inhibition of T cell response. We will examine how the effectors influence interaction between dendritic cells and T cells and describe the heterogeneity in the T cell response. Our results might provide us with new markers for infection outcome and help to develop new vaccination strategy in the future.

Project Aims

The aim of this project is to determine the impact of heterogeneous modulation of dendritic cells by Salmonella effectors on the establishment of chronic infection and superspreader phenotype of infected host. This may open new avenues in design of chronic bacterial infection therapies.

Abstract

Many infants in the world acquire two languages from birth and yet, the population of bilingual children is under-represented in scientific studies on early speech acquisition. The fundamental aim of this research project is to investigate the effect of bilingualism on the course of speech perception and production in the first year of infants’ lives, and render existing theoretical accounts on early speech development more comprehensive and generalisable. Babbling will be analysed in infants aged 8-14 months. Auditory discrimination between languages and speech sounds will be examined at 4, 6, and 12 months, using advanced neuroimaging (EEG and fNIRS) and cognitive-behavioural methods. Neurophysiological data on speech processing during the initial months of life are expected to be particularly illuminating as they should help provide deeper understanding of the developing brain’s exposure to the infant’s native language (s). The project will help to understand whether the established developmental milestones in early speech acquisition can be considered universal.

Project Aims

Run four perception and one production studies with monolingual and bilingual infants between 4 and 14 months. Check milestones in language acquisition. Gain unique insight into developmental differences and point to possible applications. Form a research team. Report findings in IF journals

Abstract

The future of sustainable development of human society directly depends on improvement in energetic and economic efficiency. Such advancement in electric power generation or propulsion requires discovery and development of high-performance materials. Following-up our recent revolutionary work (Nature, 2023) the goal is to explore a newly opened compositional space for design and optimization of cost-effective and sustainable 3D printable oxide-dispersion-strengthened multi-principal element alloys (ODS-MPEAs). The predictive power of thermodynamic calculations will be combined with rapid alloy production by additive manufacturing. Promising candidate materials will undergo accelerated mechanical testing in terms of monotonic load, creep and fatigue. Complemented by state-of-the-art multi-scale characterization and supported by the atomistic simulations, the key design aspects determining alloy performance will be assessed. Proposed multi-layered optimization approach will result in the development of new 3D printable ODS-MPEAs for use in the targeted temperature range of 800-1000°C.

Project Aims

Identification of critical aspects of material design determining behavior of 3D printable ODSMPEAs under monotonic, creep and cyclic loading at high temperatures (800-1000°C). Development of new cost-effective and sustainable 3D printable ODS-MPEA for use in extreme environment.

Abstract

Deep Neural Network models have in the recent years dominated virtually all areas of Artificial Intelligence and Computer Vision. Despite the recent success, the models are easily confused by trivial samples not present in the training set and even the largest models lack basic generalisation and reasoning abilities despite having hundreds of millions of parameters and being trained on millions of very diverse data samples – suggesting that a fundamental piece of understanding is still missing. We propose that one of the missing pieces in current models is an appropriate inductive bias – the set of prior assumptions used to generalise and make a prediction based on a finite set of training samples – and therefore in this project, we want to study inductive biases for common Computer Vision tasks and incorporate them into modern Deep Neural Networks. This will result in Deep Neural Network models which require less parameters, which are more efficient, which are less confused by out-of-distribution data samples and which require less training data.

Project Aims

1) discover existing and search for new symmetries for modern computer vision models 2) discover novel topological representations as another form of inductive bias encoding 3) introduce novel indirect low-dimensional representations 4) make the search for inductive bias more efficient

Abstract

The goal of the project is to study the mutual interaction between stars and supermassive black holes (SBHs) in galactic nuclei. Previously, we showed that the interaction with the nuclear jet can substantially affect stellar characteristics. Here we propose to extend previous studies by analyzing systematically the combined interaction of stars with both the accretion disk and the jet. Repetitive encounters will enhance stellar mass loss and hence, in addition to modifying stellar evolution, they inevitably change the accretion state of the SBH. Traditional unified models of active galactic nuclei (AGN) neglect the effect of stars. However, they can not only perturb the accretion state of SBHs, but eventually also determine it via dense concentrations – nuclear star clusters (NSCs). Comparison of the NSC properties, radio emission characteristics on smaller and larger scales as well as X-ray emission properties within the Bondi radius of the SBH are needed to comprehend the link between the NSC modulation of the SMBH accretion state and large-scale AGN feedback.

Project Aims

We will compute the effect of repetitive stellar passages through the nuclear disk-jet on both the star and the accretion of the supermassive black hole (SBH). We will compare the nuclear star cluster (NSC) properties with the SBH emission to understand the NSC effect on the large-scale feedback.

Abstract

Chirality plays an important role in chemistry, physics, and biology. Reactions involving chiral molecules often entail changes in molecular chirality. One way to visualize photo-induced chiral dynamics during chemical transformations in real time is time-resolved photoelectron circular dichroism (TRPECD). The PECD manifests itself as an asymmetry in a photoelectron angular distribution (PAD) when an ensemble of randomly oriented chiral molecules is ionized with circularly polarized (CP) radiation. The PAD is measured by time-resolved photoelectron spectroscopy combined with extreme ultraviolet CP femtosecond pulses obtained through high harmonic generation. The project aims to study chiral dynamics on femtosecond timescales, thereby advancing several research disciplines such as excited-state photochemistry and femtochirality and entails the following major goals: probing electron correlations during double ionization of chiral molecules, probing chiral changes during the photo-switching of helicenes, and the development of a theoretical framework for calculating the TRPECD.

Project Aims

1) Founding of a new research group 2) Study of chiral dynamics during chemical transformations in real time by measuring static and time-resolved PECD and PICD of doubly charged cations and helicenes 3) Development of advanced experimental setup with 3D VMI and circularly polarized high harmonics

Abstract

The analysis of extensive data of prospographical, administrative and anthropological character using advanced mathematical methods reveals changes in Old Kingdom society (2700–2180 BC) and differences between individuals in relation to their social status. The combined use of a database of officials and their titles (Maat-base) and an anthropological database (AnuBase) containing the detailed evaluation of hundreds of morphological and metric features is the initial resource in the analyses and mathematical processing. The interdisciplinary project integrating the methods of systematic data collecting and complex network analysis with anthropological study of particular individuals buried at Giza and Abusir enables us to view, newly interconnect and evaluate known data using new perspectives that significantly expand and deepen our knowledge of ancient Egyptian society at a number of levels: an individual (physical appearance, physical activity, career length) – the family or community (family ties, nepotism) – the whole society/population (demography, changes over time).

Project Aims

The main goal is to study individuals and the operation of society in Egypt in the third millennium BC. The principal task is to define possible relations and links between anthropological data and the social status, family kinship or demographic profile of the population using mathematical methods.

JUNIOR STAR 2023

Abstract

The proposed project addresses the development of radiation detection systems for real-time measurement of radiation field characteristics, based on hybrid pixel detectors of the Timepix family. This development is driven by the needs of physics experiments at accelerators and in space. Particle type identification accuracy and precision of trajectory reconstruction shall be improved by utilizing novel chip technology and sensor materials in combination with state-ofthe-art computer science methods. Artificial intelligence will be used for exploiting the characteristic features of particle traces in the sensors. Besides 3D particle trajectory and dE/dX measurement, detector segmentation and an expected time resolution of 200 ps also provide information about the direction of particle flight. Developed detection systems and data evaluation methodology will be applied also to the mixed radiation fields found in the ATLAS and MoEDAL experiments at the LHC, and in Space. The expected outputs are 10-15 publications in impacted journals and 2-3 conference proceedings.

Project Aims

  • Develop novel detector systems and algorithms for real-time particle identification and trajectory reconstruction;
    • Use the developed detector system and evaluation methodology for fundamental research in high-energy physics and space applications.

Abstract

“With recent developments in instrumentation, phase plates and machine learning algorithms, the field of electron microscopy and spectroscopy is at the edge of a new era. In this project, we will study shaped electron beams as revolutionary probes, which will make electron microscopes more versatile and cheaper, and enable novel applications. We will theoretically explore phase plates needed for the preparation of shaped beams and alternative imaging and spectroscopic methods available with these unconventional probes. We will introduce and optimise designs of tunable light- or microelectronics-based electron phase concerning selected applications. We will focus on fast and damage-free imaging and spectroscopy, probing lowenergy excitations beyond the usual selection rules and studying optical dichroism, everything down to the atomic scale. Since electron microscopes are essential diagnostic tools in many areas of research and development, the achievements of the project will have a significant impact on the whole society.”

Project Aims

Theoretical development and optimisation of fast and versatile electron phase plates for generation of shaped beams. Theoretical proposal of applications of such beams in fast electron imaging and spectroscopy of low-energy optical and vibrational excitations.

Abstract

Migrastatics represent a new class of drugs with great potential to improve the outcome of current cancer treatment strategies by inhibiting the metastatic behaviour of cancer cells. Actin polymerization is one of the potential targets for migrastatics. The aim of the project is to develop new compounds with antimetastatic activity based on inhibition of actin polymerization (direct or indirect). Analogues of cytochalasins, that directly inhibit actin polymerization, will be developed based on virtual screening and fragment growing. Inhibitors of ARPC1, a subunit of the Arp2/3 complex and actin polymerization regulator, will be developed including specific inhibitors of ARPC1 isoforms. Finally, PROTACs targeting the Arp2/3 complex and its subunits will be synthesized and their effect on cancer cell invasion will be studied. The screening of the new compounds will be performed in close collaboration with Prof. Jan Brábek (BIOCEV, Vestec, Czech Republic).

Project Aims

Development of cytochalasin analogs Development of Arp2/3 complex inhibitors that target an ARPC1 subunit Development of specific binders to ARPC1 subunit isoforms Development of proteolysis-targeting chimeras to modulate the function of the Arp2/3 complex

Abstract

“N-methyl-D-aspartate receptors (NMDARs), a subtype of ionotropic glutamate receptors, bin synaptically released neurotransmitter glutamate and mediate fast excitatory synaptic transmission at the majority of synapses in the mammalian central nervous system. NMDARs play a key role in synaptic plasticity and neuronal development. We will use a combination of single-molecule FRET, electrophysiology, molecular biology and computational methods to study human NMDAR conformational rearrangements underlying receptor activation and desensitization. On this basis the project aims to build a quantitative model of NMDAR activation, reveal how the individual conformational states and transitions in the receptor activation pathway are affected by human de novo disease-associated mutations of the GRIN genes and how this relates to altered receptor cell-surface expression. Finally we aim to reveal how the impaired NMDAR signaling can be rectified by novel subunit-selective modulators.”

Project Aims

To quantitatively characterize NMDAR conformational changes in the course of receptor activation and desensitization, to uncover the structural basis of human GRIN diseaseassociated mutations, and to explore how the impaired NMDAR signaling can be rectified by novel subunit-selective modulators.

Abstract

“Determining genetic underpinnings of adaptation is a major challenge of evolutionary biology. Repeated environmental adaptation offers powerful naturally replicated study systems, yet varying fraction of the genome exhibiting convergence precludes generalization. Multiple genomic and functional factors have been proposed to determine genomic convergence, but their relative importance is blurred by case-specific focus of the studies and varying evolutionary timescales. Leveraging 13-fold independent colonization of challenging toxic soil by model family Brassicaceae, I aim at systematic assessment of the factors underlying genome convergence and thus evolutionary predictability. We will combine population and structural genomics with transcriptomic and reverse genetic validations to characterize the factors determining genomic hotspots of convergence and test the hypothesis of their varying importance with divergence. The project will identify general drivers of convergent genome evolution in nature and inform evolutionary predictions essential for efficient breeding and conservation.”

Project Aims

Identify candidate hotspots of convergent adaptation along a broad divergence continuum. Quantify relative importance of the genomic and functional predictors of convergent hotspot loci. Functionally validate phenotypic and fitness effects of the convergent hotspot loci.

Abstract

“I argue that the meta-analysis methodology used in observational research entails a bias, one that stems from a reliance on reported precision which often exaggerates real precision. I will show that, when applied to all meta-analysis contexts, a method inspired by instrumentál variables used in economics corrects for the bias. In meta-analysis, studies reporting more precision get more weight. Yet more than 20,000 metaanalyses have been conducted in social sciences, mostly synthesizing observational research, where researchers have control over the precision measure they report. Hence, reported precision is endogenous. I challenge the assumption that observational studies reporting more precision are more informative and less biased. While I focus on social sciences, the results will apply to the 100,000+ meta-analyses in other fields that have also relied on observational research. Spurious precision has dramatic consequences not only for meta-analysis methodology and structural models calibrated using meta-analyses but also for the entire practice of evidence based policy.

Project Aims

“I will present a novel meta-analysis estimator and gauge its performance using i) Monte Carlo simulations, ii) comparisons of meta-analyses with pre-registered Many Labs replications, and iii) comparisons among many meta-analysis estimators applied to a large number of metaanalysis datasets”

Abstract

“The purpose of this project is to better understand the development of mathematics in Prague during the first half of the 19th century by elucidating the motives (e.g., practical) and factors (e.g., socio-institutional) that led to certain practices being set as a norm but also to the emergence of new mathematical knowledge. For this we take as case study the University of Prague and Bernard Bolzano, both of which were sui generis actors at the time, and we propose a methodological approach to study the dynamics of mathematics that brings together elements from the latest trends in the history of mathematics and mathematics education, the philosophy of mathematical practices, the studies on mathematical cultures and the textual studies.”

Project Aims

“Study the mathematical practices in Prague and in Bolzano’s work in the context of European mathematics of the first half of the 19th century. Create a Digital Archive of Bolzano’s mathematical manuscripts. Encouragement of ‘citizen science’ and education through public engagement.”

Abstract

“Scientific computing inherently involves multiple sources of inexactness, from discretization or simplification of the problem, to noisy data, to rounding errors, to stopping computations intentionally to improve efficiency. The state-of-the-art approach is to analyze different sources of error separately. This modular approach is not only potentially hazardous, but also misses potential opportunities to improve performance by combining multiple sources of inexactness. Developing reliable, efficient approaches for exascale matrix computations requires filling this gap. This project will break the modular approach to the analysis and design of algorithms for inexact matrix computations by rigorously analyzing how different errors interact while being propagated through a computation and their effect on numerical behavior and solution quality. Our holistic approach, rooted in rigorous theoretical analysis, will lead to new algorithms for exascale problems that exploit inexactness to balance performance and accuracy. ”

Project Aims

“This project will: 1) rigorously analyze matrix computations subject to multiple sources of inexactness and 2) to build on insights from this analysis to develop new algorithms targeting exascale machines that exploit inexactness to achieve both performance and accuracy. ”

Abstract

“Drones are already changing many industries like package delivery, inspection, or search and rescue. This research project will focus on answering fundamental questions that arise from high-speed flight of quadrotors in cluttered environments. The motivation for this project is the search and rescue scenario which requires the drones to be as fast as possible to quickly find survivors after natural disasters. We will focus on pushing the boundaries of the drones’ autonomy in planning and control for agile quadrotor flight. Current approaches struggle with online trajectory planning and control that would use full agility of the quadrotors and thus minimize the time of flight. We plan to developt planning and control methods that overcome this limitation and thus significantly improve the efficiency of drones in such tasks. Furthermore, we will develop novel approaches for online mission planning over multiple targets, e.g. estimated locations of survivors in the search and rescue, that would (contrary to existing work) account for cluttered environments and limited battery capacity.”

Project Aims

“We will develop novel methods in

1)Online trajectory planning for minimum-time flight in cluttered environments

2)Robust model-based and learning-based control approaches for an agile flight amongobstacles

3)Multi-goal mission planning with minimum-time objective and constrained battery capacity”

Abstract

Stem cells reside in specialized microenvironments or “niches” that maintain stem cell function during the growth, maintenance, and repair of tissues. My project aims to leverage powerful genetic, imaging, and lineage tracing tools of zebrafish with single-cell sequencing to investigate a recently discovered specialized fibroblast population (Fabian et al, NatCom, 2022) that may act as a niche for long-term skeletal health. As several of the genes enriched in this niche cause craniofacial malformations when mutated in humans, my work will provide an important new insight into how proper niche function ensures normal development and maintenance of the head skeleton.

Project Aims

“This proposal aims to characterize a novel population of cranial neural crest cells in the vertebrate face and describe their function as a niche supporting the skeletal stem cells.”

Abstract

“This proposal aims at development of novel ab initio simulation tools for treatment of amorphous and crystalline organic semiconductors. My research background enables me to target an unprecedented sub-chemical accuracy of predictions of structural properties and phase transitions. Exploitation of fragment-based ab initio Monte Carlo and quasi-harmonic models grants a sound physical consistency, minimizing any empiric inputs. I will address extending the applicability of the developed methodology to bulk phase of large molecules, typical for organic semiconductors. These compounds nicely illustrate the applicability and accuracy limits of the state-of-the-art ab initio modelling of molecular materials concerning molecular size, specific interactions, importance of the amorphous state, and dependence of the charge-carrier mobility on subtle variations of the structure. Proposed research will enable to accurately predict melting and vitrification points, polymorphism, crystallization driving force or conductivity of cutting-edge materials with optoelectronic relevance.”

Project Aims

Development of ab initio simulation tools to predict structure, phase behavior and chargé transfer of amorphous and crystalline organic semiconductors with an unprecedented subchemical accuracy, being applicable also for large molecules typical for real organic semiconductors.

Abstract

The challenges related to integration of foreigners are very important and timely in various
societies. Negative attitudes toward out-groups are associated with social problems, such as
racism, discrimination, social exclusion, violent crime and extremism. Czech Republic is
currently facing unprecedented influx of refugees from Ukraine and most of the Czech
adolescents will start sharing classrooms with foreigners for the first time in their life. The main aim of this project is to examine the effect of education and classroom environment on the development of attitudes toward out-groups with a 4-wave panel survey that will track
individuals during their high school education. Literature on the liberalizing effect of education distinguishes three causal mechanisms: cognitive sophistication, learning liberal values, and gaining psychological security. This project aims to test the mechanisms on panel data that will include critical thinking assessment, sociometric status, dynamics of social relationships in classrooms, learning content, methods, and teachers’ characteristics.

Project Aims

“This project aims to employ a 4-wave Czech high school panel survey to examine the longitudinal effect of education, classmates and teachers on the development of attitudes towards out-groups in adolescence.”

Abstract

“This research proposal employs state-of-the-art high-resolution atmospheric datasets and cutting-edge theoretical methods for internal gravity wave (GW) detection and wave-mean flow interaction to revisit and advance our understanding of GW effects on atmospheric dynamics, composition and coupling across atmospheric layers. GWs exist on a variety of scales, but typically a significant portion of the GW spectrum remains unresolved in global weather prediction or climate models and the GW impacts need to be parameterized. Our knowledge on GW impacts ranging from regionality of precipitation to the evolution of the ozone layer has been so-far based on their predominantly parameterized effects. Analyzing the resolved GW effects will improve our understanding on the forcing of selected atmospheric phenomena, but will also put additional constraints on the current GW parameterizations by showing to what extent their effects (and our current understanding) are artificial. This will help us to modify GW parameterization schemes with an ultimate goal of improving future climate predictions.”

Project Aims

“Evaluation of the parameterized gravity waves (GWs)-resolved dynamics interaction in models based on GW resolving simulations. Revision of climate GW effects based on GW resolving simulations. Development of GW parameterizations without artificial effects on model dynamics and transport.”

Abstract

Targeted therapy is the golden grail of contemporary cancer chemotherapy. Despite that, the
use of targeted therapies in clinical practice is impeded by several drawbacks including
inadequate pharmacokinetics and side toxicity. These limitations might be circumvented by
enhancement of selectivity and efficiency of therapeutic modalities. Therefore, we plan to
benefit from a concept of bioorthogonal chemistry to develop biocompatible ferritin-based
nanocatalysts for in situ extracellular liberation of cytotoxicity of non-toxic prodrugs. To achieve this, we plan four work-packages: i) engineering and production of recombinant ferritins for delivery of catalysts, ii) synthesis of catalysts for BOOM and IEDDA reactions and their encapsulation into ferritins, and synthesis of prodrugs, iii) investigation of reactivity of nanocatalysts in cell-free and cell culture conditions. and iv) examination of an anticancer
efficiency of bioorthogonal pairs in murine model. The proposed project will open up new
avenues for exploitation of novel hybrid nanocatalysts in precise anticancer therapy.

Project Aims

“The proposed project aims on a design and functional validation of novel biocompatible hybrid ferritin-based nanocatalysts for in situ extracellular activation of prodrugs towards development of a new generation of efficient anticancer therapeutic modalities.”

Abstract

“Organic solar cells exhibit remarkable optoelectronic properties similarly to naturally occurring light-harvesting complexes in photosynthesis. However, comparatively with their inorganic counterparts, they yield relatively low efficiency due to their short exciton and charge diffusion length. The project aims to investigate fundamental laws governing charge mobility in lightharvesting molecular nanomodels. To this ambition, I propose to combine templated-assisted synthesis of molecular nanorings and cryogenic atomic-scale probe microscopies for probing the effects of molecular organization on electronic communication, with single-electron sensitivity and sub-angstrom resolution for a complete control of their coherently delocalization of charge. This combination will allow us to understand the relation between structure, aromaticity, and charge mobility for single macrocycle. The proposal entails transformative potential for the field of organic solar cells down to the nanoscale.”

Project Aims

“To combine template-assisted synthesis with atomic-scale scanning probe techniques to experimentally control and visualize charge delocalization in molecular nanorings. Such combination will provide fundamental insights into the charge transfer processes of organic solar cell nanomodels.”

Abstract

The processes involved in Portland cement (PC) production account for around 7% of global
CO2 emissions. Reactive magnesia-based cements have comparable properties to PC, but
much lower environmental impact. In particular, magnesium oxychloride cement (MOC)
composites, with their CO2-neutral footprint, could provide the basis for a novel route to
sustainable construction materials. However, there are challenges to be overcome, the main
one of which is the poor water resistance of MOC, which results in the rapid degradation of its mechanical properties. The novelty of our approach lies in incorporating combinations of 2D carbon-based nanomaterials and selected secondary waste fillers into the MOC matrix in order to obtain high-strength and water-resistant composites. Furthermore, the excellent recycling potential of these MOC composites will be exploited by the design of thermal and mechanical methods that deliver a zero-waste cradle-to-cradle lifecycle. While this project is high-risk, success will offer an entirely new route in the design of sustainable construction materials.

Project Aims

“The main aim of the project is to develop high-strength, water-resistant, CO2-neutral, and completely recyclable magnesium oxychloride cement composites with 2D carbon nanoadditives and secondary fillers as a new group of materials for Portland cement replacement. ”

Abstract

“Organisms often evolve similar adaptations to similar environments in the process of convergent evolution, indicating that the trajectory of phenotypic evolution is amenable to predictions. Whether the genomic trajectories of convergent organisms are parallel – and thus predictable in principle – is unclear due to the scarcity of genomic evidence from convergent organismal groups. To answer these questions, I will establish a model system consisting of rove beetles (Staphylinidae) and scuttle flies (Phoridae) that adapted more than twenty times repeatedly to live in symbiosis with termites. Using phylogenetics, comparative genomics, transcriptomics, and microtomographic reconstructions of phenotypes, I will infer the extent and the timescale at which parallel patterns of genome evolution accompany the evolution of convergent adaptations. The integrative analytical approach applied to a massively convergent model group of organisms will give me an unprecedented capacity to assess the repeatability of evolution.”

Project Aims

“1) Uncover the extent, time-scale, and hierarchical level of genome sequence evolution accompanying convergent phenotype adaptation to a symbiotic lifestyle.

2) Determine whether the genetic changes in convergently adapted organisms are repeatable”

Abstract

Layered low-dimensional materials are auspicious for application in all areas of nanotechnology since properties of these materials depend on the degree of exfoliation. Also, catalysis seems to be an exciting application as a superior effect of a two-dimensional (2D) support on the activity of metal nanoparticles due to specific metal-support interactions. This project is focused on preparation and chemical modification of layered materials based on Si, Ge, and SixGe(1-x) mixtures. The aim is to prepare 2D hundreds-of-micron-sized sheets and nanometer-sized quantum dots (QDs) with high optical and chemical uniformity. Functionalization of the prepared uniform low-dimensional materials allows the application of these materials in fundamental research of phenomena typical for heterogeneous catalysis: I) Study of the exclusive effect of 2D support on the enhanced activity of metal nanoparticles and II) Assessment of accessibility and interconnectivity of pores space in conventional catalysts using 0D QDs with varying size as a pore space probe.

Project Aims

  1. Synthesis and chemical modification of layered materials based on Si, Ge, and SixGe(1-x) mixtures 2. Assessment of chemical and optical uniformity 3. Platinum nanoparticle deposition on 2D material 4. Study of the metal-2D support interaction 5. Mass transport visualization in pore space

Abstract

During the interaction of a high-power laser beam with a target, extreme intense electromagnetic pulses (EMP) in the MHz-THz band reaching up to hundreds of kV/m are emitted. Notwithstanding that such effects have been observed in recent decades, the physical mechanisms of EMP production still are not satisfactorily explained. Moreover, the strong EMP causes significant interferences in signals and damages the diagnostic systems. On the terawatt and petawatt laser facilities, these problems are so important that the systematic research of EMP was included in the scientific program of world-class institutions e.g. the Rutherford Appleton Laboratory and ENEA Frascati. The EMP is the current topic also in the Czech Republic due to the commissioning of the ELI Beamlines laser facility where highrepetition laser systems operate with a rate of tens or hundreds of pulses per second. Therefore, in the frame of this project, we will perform a systematic characterization of the EMP for various parameters of the laser beam and target using a comprehensive system of EMP and plasma diagnostics.

Project Aims

The aim is to understand the processes responsible for the EMP emission, characterization of the EMP for various parameters of the laser and target, optimization of established diagnostics and development of new diagnostics methods, improve measures against EMP, an effort to find an application.

Abstract

“We focus on a pressing question in evolutionary ecology: Is migratory behaviour to breed at higher latitudes still advantageous? Despite the historic benefits of migration, currently numerous migratory animals experience higher predation, more parasites but lower food supply on their breeding grounds than in earlier decades, questioning migration profitability. To address this emerging issue, we propose a comprehensive investigation of migration profitability, combining experimental, observational and comparative approaches, novel technologies and robust independent datasets. We will study latitudinal gradients in predation,

parasites and food supply in relation to migration profitability and population dynamics, using shorebirds as an excellent model system at 16 established study sites across both hemispheres. We anticipate uncovering the ecological and demographic drivers of changing benefits for migratory behaviour. This project is significant by disentangling the impacts of climate change and human pressure on a globally important issue as well as helping practical conservation.”

Project Aims

We will: 1) quantify predation, parasites and food supply using the same protocols across latitudes; 2) track breeding productivity and migration routes of individual birds from different populations; 3) combine experimental, observational and comparative investigations of migration profitability.

Abstract

More and more aspects of daily life, generally, and of contractual relations, specifically, are (partly) governed by artificially intelligent machines. Though the technology is still in its infancy, prominent examples that suggest the need for regulation are already emerging. Regulation, however, also requires a deep understanding about whether humans interact with machines differently as compared to their interactions with other humans, and if so, how. Research on behavioral micro-foundations of these human-machine transactions is surprisingly scarce. The proposed research project will contribute to closing this gap by conducting a set of experiments specifically designed to reveal how human behavior adapts to the presence of machines in social dilemma situations and coordination problems. The results will be used to draw conclusions for legal reform and, more broadly, for implications for institutional design.

Project Aims

The main goal of the research project is to quantify how human behavior changes when artificially intelligent machines are involved in social dilemma situations and coordination problems. A subsequent goal is to draw policy implications to smooth the transition to machinedriven economies/societies.

Abstract

This project will create novel mathematical methods that facilitate a better understanding of the properties of massive networks. Such networks appear in many real-life situations including links between Internet routers, user connections on social networks, or protein-to-protein interactions inside a molecule. Large networks are, however, also fundamental to many open problems in pure mathematics. In particular, they are a central object in extremal combinatorics. One of the key elements of this project focuses on providing new techniques of using a computer in order to find mathematical proofs. Another important aspect of the project revolves around randomness, which turns out to be extremely effective in various mathematical and computer science scenarios. In fact, for many problems involving decisions that were solved in this randomized way, we currently do not know anything that would perform even nearly as good as random choices do. In this project, we will study so-called pseudorandomness – a systematic way that aims at catching up with the randomness by being smart.

Project Aims

Find novel and extend current methods for analyzing massive combinatorial structures (such as large networks), and apply these methods to open problems in discrete mathematics. Investigate new ways of using computers to prove theorems in mathematics.

Abstract

The project aims to analyse internal changes in the Mongol-Turkic multi-ethnic contact areas of Mongolia to the identities of rural communities as expressed in the memories of belonging and orally transmitted awareness of local geography and in relation to the land use strategies of mobile pastoralists (evolvement of movement patterns). The project is based on the innovative connection of methods of oral history and research of the oral tradition as a source of history in addressing changing identities and adaptive strategies of marginalized communities, ongoing metamorphoses in unprofessional parts of oral heritage and land use evolvement, which is expected to provide important data for current environmental issues. Outputs of the project include digital databases a) of seasonal moves of mobile pastoralists during the last hundred years, and b) of the endangered oral tradition, and c) an analysis of the main research problems in a comparative monograph assessing the current state of the local history-related oral tradition oscillating between transmitted and constructed memories.

Project Aims

The aim is basic interdisciplinary research of oral history and oral tradition. Based on data collected within own fieldwork, the project will analyse non-invasive methods to understand the dynamics of changes in the movement patterns and community identities of endangered ethnic groups in Mongolia.

 

 

JUNIOR STAR 2022

Abstract

Cell division is an essential process for any living cell on Earth. Cell division is finalized by cytokinesis, which results in two daughter cells. Plant cytokinesis is fundamentally different from that of animal and fungal cells. Plant cells evolved a unique membranous compartment, the cell plate. The cell plate grows in an inside-out manner by which it separates two daughter nuclei. In this highly multidisciplinary project, we aim to unravel unprecedented details of cell plate development, which remain unknown. We will use cell plate development as a time axis to study the dynamic interplay between proteins, lipids and cell wall polysaccharides. We will use continuously dividing synchronized Arabidopsis cell culture. We will employ chemical crosslinking mass spectrometry, metabolic labelling and state-of-the-art fluorescence microscopy. We aim to solve the molecular architecture of the enigmatic callose synthase complex using an integrative structural approach. Our unique methodology will identify new players in plant cytokinesis and create a 4D map of cell plate development.

Aims

The overall aim of this research project is to describe the spatiotemporal dynamics of cell plate development at the level of individual proteins and construct a 4D map of cell plate development.

Abstract

The changes in terrestrial hydrological cycle directly influence water availability. It is expected that global warming will accelerate the hydrological cycle, resulting to new challenges for human societies. In this project we will analyze and model the variability of the terrestrial hydrological cycle in a combination of multi-scale data-driven methods with process-based climate and hydrological modeling. Our aim is to assess the present and future acceleration rate and understand how it is connected to changes in water availability. We will combine paleoclimatic data and contemporary observations, develop new stochastic methods, and utilize the recent advances in process attribution to understand how water availability responds to the hydroclimatic fluctuations.

Aims

“1) Assessment of the current terrestrial water cycle acceleration and its statistical significance.
2) Development of a multi-scale stochastic model for hydroclimatic variability.
3) Attribution of changes in water availability to the processes affected by the acceleration of the hydrological cycle.”

Abstract

This project is about developing insights in the most active research area in economic theory – information economics – to help understand the informational transformation that many sectors of the economy and society are undergoing. It will depart from previous research in this field by focusing on the interplay of information and power – such as in questions of privacy, of the ownership of data and algorithms, and the centralization or decentralization of data storage and processing. This includes understanding: (i) How the possibilities of the Internet can be harnessed for efficiency-enhancing information revelation and exchange, (ii) how the mandatory disclosure (or non-disclosure) of information shapes economic and societal outcomes, (iii) how we can most usefully model the economic value of data and algorithms and their ownership, and (iv) how the centralization of data storage and processing interacts with mechanisms of social and economic control.

Aims

To gain insights in the economic theory of information that can help harness the possibilities of the Internet for society and solve the problems it creates. To establish CERGE-EI and the Czech Republic as an international center of excellence and focal point for this research.

Abstract

Biomacromolecular structural data is a highly valuable research resource. Reconstruction of whole organelles and cells is the cutting-edge research in this area, but a community strongly lacks services for their efficient visualization and modelling. In this project, we will develop a Cell* web platform, which will solve this gap. Moreover, Cell* will show the structures in the context of experimental data and biological and chemical properties. It will provide an insight into organelle and cell biology through the integration of structural models. Cell* will be a breakthrough solution also due to its capabilities to visualize dynamics of cell-sized structures and perform their animations. In this project, I will use my experience with the development of LiteMol and Mol* web tools for the visualization of large biomacromolecular assemblies and complexes. LiteMol was published in Nature Methods and it was the main viewer in PDBe. LiteMol was replaced by Mol*, which is now a main structure visualization tool in PDBe and RCSB PDB. I have been a lead developer of both LiteMol and Mol*.

Aims

Develop a Cell* web platform for visualization, modelling, and dynamics of organelle- and cellsized structures. Cell* will also enable visualization of experimental data and biological and chemical properties (annotations).

Abstract

The active layer and permafrost are the building elements of the periglacial environment in polar regions. Their parameters like temperature, moisture, or active layer thickness respond very sensitively to climate oscillation, making them valuable indicators of the effect of climate change on terrestrial ecosystems in the polar environments. Therefore, a long-term monitoring of the active layer thickness and permafrost temperature belongs to principal questions of Antarctic research. The proposed project will assess the current state and evolution of periglacial dynamics in the ice-free areas of the Antarctic Peninsula. Extensive fieldwork, laboratory and analytical methods will provide a detailed evaluation of the ground physical properties (moisture, texture, thermal properties), ground temperature and active layer thickness. Available data will allow us to reconstruct the past state and predict the possible evolution of permafrost temperature and active layer thickness in the period 1950-2100 and determine the effect of ongoing climate change on these parameters.

Aims

The project aims to assess the dynamics of the periglacial environment at present, reconstruct its state in the past and predict its development in the future until 2100 in the Antarctic Peninsula region using monitoring of soil temperature variability, moisture and the active layer thickness.

Abstract

Inter-species co-existence, between a microbe and its host, underpins much of the complexity of the natural world. Ticks, blood-feeding Arachnids, harbour a bacterial ally, residing within mitochondria of several tissues. Until now, ticks and symbionts have been rarely studied together as an interacting system. The functional context of this alliance is thus largely unexplored. This proposal aims to uncover the molecular interface of “species bridging”, i.e. integration of the symbiont metabolism in tick physiology. Using a holistic approach that blends state-of-the-art microscopy, multi-omics data, and RNAi with a newly developed comparative model of symbiont-free ticks, we propose to do an innovative structural and functional exploration into the interaction landscape of the bacterium and its host. This project will also provide an in-depth insight into the tolerance and resistance strategies of ticks against viruses and bacteria, allowing the multi-species co-existence.

Aims

“1) characterisation of symbiont-tick molecular and cellular interactions
2) identification of haem- and cholesterol-distribution network in ticks
3) development of Crispr-Cas9 delivery into ovaries using tick vitellogenin fragments”

Abstract

In the project, the most recent methods of experimental dynamics will be combined with the state-of-the-art lab-based in-situ X-ray imaging to get an unprecedented insight into deformation behavior of complex materials at intermediate and high strain rates. A flash X-ray system and high power X-ray tube will be employed together with high speed imaging equipment (high speed cameras and detectors) to investigate the internal processes in the materials during dynamic loading. Significant effort will be aimed at novel cellular and layered materials filled with strain rate sensitive fillings while the effects of shear thickening fluids and fluids with nanoparticle inclusions will be investigated in particular. In this field, the combination of X-ray imaging with instrumented dynamic experiments will reveal fundamental aspects of the deformation response of the materials and their failure mechanisms. The results will be used to formulate and validate theoretical assumptions and models with a special aim on the internal processes that can be conventionally inspected only indirectly.

Aims

The main goal of the project is to reveal the crucial aspects of the deformation response in complex materials at intermediate and high strain rates through a combination of novel experimental methods and techniques in impact dynamics with state-of-the-art lab-based in-situ X-ray imaging.

Abstract

This project will investigate reaction networks at phase interfaces and develop the concepts of molecular recognition, semiconductor electric polarization and molecular epitaxy towards enantioselective catalysis, photoredox catalysis and planar heterojunctions by doubly dynamic self-assembly. Phase interfaces are omnipresent and always dictate self-organization of species in their proximity. Here, I propose to take advantage of the interphase energy together with stimuli-responsive reaction networks to achieve a breakthrough concept: functionalitydriven dynamic self-assembly at phase interfaces. We will study how the molecules “feel” the presence of the phase interphase, the energy/charge transfer between them and the other phase and how they assemble to form a phase on their own. We will demonstrate the potential of this approach by achieving enantioselectivity in generally achiral transformations, electrochemically promoted reactions without applied electric potential and total self-assembly of planar heterojunctions from a single reaction network.

Aims

Develop methodology for stimuli and composition instructed self-assembly on surfaces and phase interfaces driven by functionality of the assembly, exploit the findings for heterogeneous organocatalysis, photoredox catalysis and optoelectronic devices (e.g. photovoltaics, diodes).

Abstract

DNA replication is fundamental to cell proliferation, but its malfunctions can cause genome instability and trigger diseases including cancer. DNA replication initiates at replication origins by the formation of pre-replicative complexes (pre-RCs). The pre-RCs are essential drivers of replication forks; however, the mechanism(s) of pre-RCs formation and their precise roles in safeguarding genome integrity is poorly understood. I have recently discovered a molecular pathway that couples pre-RC assembly with proper DNA replication dynamics. Building on these findings, I propose to address here a central hypothesis that ‘the molecular homeostasis of replication origins is a key component of error-free DNA replication’. Therefore, using mammalian cell culture models coupled to state-of-the-art set of coherent cell biology, genomics and proteomics-based experiments, I will investigate the maintenance, regulation, and novel functions of replication origins. These experiments will illuminate the fundaments of DNA replication and reveal mechanisms counteracting genome instability in disease.

Aims

“1) The role of pre-RCs in maintenance of replication origins in ensuing cellular generations
2) The determinants of distinct biochemical properties of parental and nascent DNA replication origins
3) The contribution of origin licensing pathways to the polyploidization during cardiomyocytes maturation”

Abstract

The main obstacle which hinders humanity from building sophisticated nanomachines, such as molecular computers, is the lack of scaleable nanofabrication methods allowing precise assembly of many different molecular components. Living nature solves this problem using self-assembling and template-assisted synthesis driven by biopolymers such as DNA, RNA and proteins. In this project, I will develop methods for scalable bottom-up fabrication of molecular circuits on ionic substates in ultra high vacuum (UHV) inspired by these biological principles. This will be achieved by computational survey of templated synthesis pathways, and computer aided design of novel polymers (inspired by DNA) providing templates for the assembling and synthesis. To facilitate the design, I will create a multi-scale simulation software dedicated to exploration of self-assembling and template-synthesis pathways on ionic substrates. Such software will benefit the whole emerging field of on-surface chemistry, which currently lacks specialized tools comparable to those used for molecular docking in biochemistry.

Aims

“1) Develop specialized software for computational survey of templated synthesis processes on ionic substrate in vacuum
2) Design a polymer template applicable for driving templated synthesis and self-assembling of molecular circuits on ionic substrate”

Abstract

The aim of our materials research project is to experimentally establish interlinked new paradigms in crystallography, band structure, and electronics in multipole collinear antiferromagnets. Using diffraction and microscopy measurements up to the ultimate atomic resolution, we will demonstrate unique crystallography signatures of the multipole antiferromagnets which are beyond the established nomenclature of magnetic symmetry groups. They result in a fundamentally new form of a wavevector-dependent spin-splitting, which has been omitted in the band theory of solids, and which we will elucidate by spectroscopy measurements and ab initio calculations. We will demonstrate that these spin-split bands in the dipole-free antiferromagnets generate conserved highly-polarized spin currents, which are analogous to spin currents driving reading and writing functionalities in ferromagnetic memory devices. Beyond spin-electronics, we envisage impact of the project on fields ranging from macroscopic quantum and topological phases to dissipationless microelectronics.

Aims

We will synthesize thin films of multipole collinear antiferromagnets, and by their experimental research establish new interlinked chapters in crystallography, band structure, and electronics, with the potential to outgrow science and technology fields based on traditional dipole ferromagnets.

JUNIOR STAR 2021

Abstract

The core of the project is to is to study the thermal behavior of high-performance textiles, describe the mechanism of heat transfer in fibrous structures under extreme conditions and developing a general, scientifically supported, methodology of constructing thermal insulation layers. To determine the heat resistance of the fabric in cold conditions in accordance with standards, the losses of heat conduction are negligible and convection and radiation have to be considered. Conventional devices for evaluation of thermal resistance of clothing are based on the measurement of thermal conductivity under standard climatic conditions, which is not useful for extreme conditions. For these reasons, the project also includes the development of the measuring tunnel, which can be used to measure the total heat loss of textiles below freezing temperatures. In construction of the new heat insulating layers, the materials which reduce heat transport by radiation will also be observed. A prediction system for thermal insulation properties of the textile layers will be created.

Aims

The aims of project are: solving of heat transfer problems in textiles; creation of system for construction of thermal insulation layers; development of devices for thermal characterization; advanced materials for effective thermal insulation; creation of thermal comfort prediction system.

Abstract

The notion that groups of Elbe-German tribes were concentrated in a region north of the Danube has been contested by the discovery of vast necropolises, the study of which has great potential to shed light on cultural-historical developments in the 6th century. The subject of this project is interdisciplinary research into this population. The drawing of archaeological and historical conclusions will be preceded by non-destructive prospection, excavation, data heuristics and analytical evaluation using geographic information systems; a wide spectrum of natural-science analyses – standard anthropological analysis including paleopathology and carbon and nitrogen isotope analysis – will be applied to ascertain the population’s diet; strontium isotopes will be analysed to exactly prove migration of groups of population. At the same time, international collaboration, mainly in the area of genetic research, will take place. Regular presentation at international conferences is planned. The outputs will include three studies and a final summarising monograph in English by the proposer.

Aims

The aim of this project is to ascertain new crucial findings regarding the population and culturalhistorical development in 6th-century Moravia by means of a comprehensive assessment, employing the natural sciences to the maximum extent, of relevant co-called Lombard necropolises.

Abstract

Machine-extracted representation of visual content in images and videos is used in computer vision to help estimating human-perceived visual similarity. Visual representation is important in a variety of domains and needs to capture multiple notions of visual similarity, each relying on different perceptual factors. These factors are typically captured by separate models, which results in systems that use model ensembles and are demanding in terms of processing power, processing time, and storage cost. One goal of the project is to propose new ways for designing and learning universal multi-purpose models to extract visual representation that is appropriate for a variety of cases. Representation models will be trained with deep learning, which is typically demanding in terms of labeled training data, especially if multiple purposes are targeted. Therefore, another goal of the project is to reduce the need for supervision by employing large collections of unlabeled examples and exploiting the structure of the representation space in semi-supervised and active learning.

Aims

“1) learn universal representation models that deliver high performance in a range of tasks and domains
2) learn representations that enable new ways of exploring large collections of visual content 3) perform deep representation learning with fewer labeled and more unlabeled data”

Abstract

Chemical industry heavily relies on petrochemical feedstock for raw materials. This puts strain on our natural resources and damages the environment. The use of carbon dioxide (CO2) in chemical synthesis can decrease our overreliance on petrochemicals, mitigate their devastating effects on the environment and help in the development of greener chemistry and circular economy. This project aims at the development of frustrated Lewis pair catalysts for reductive coupling reactions of CO2 with amines. Herein, CO2 replaces the industrially used petrochemical-based and toxic reagents such as carbon monoxide, formaldehyde, methanol and methyl iodide. Hydrogenation catalysts based on frustrated Lewis pairs are proposed as a bridge to main group hydrides, which recently proved as efficient reducing agents for the proposed reactions. Special attention will be given to the required properties of frustrated Lewis pairs for applications in CO2 reduction reactions and the mechanisms of the reactions.

Aims

The aim of the project is to develop and understand reductive coupling reactions of carbon dioxide with amines, which utilize dihydrogen as the reducing agent and frustrated Lewis pairs as hydrogenation catalysts.

Abstract

The Born–Oppenheimer approximation simplified condensed matter physics by separating the motion of atomic nuclei and much lighter electrons. The violation of this concept was considered rare and lead to emergent functionalities such as multiferroicity, polar order and superconductivity. In a recent study, we have demonstrated an abundance of magnetoelastic (ME) interactions in common intermetallic compounds, revealing that interactions between nuclei and electrons are far more common. We believe that hidden ME modes are responsible for many unresolved inconsistencies across condensed matter physics. A detailed description of these phenomena will lead to rapid scientific progress. The project seeks to experimentally exploit ME modes in heavy fermion systems and iron pnictides, using inelastic neutron scattering (INS), which is able to uniquely unveil ME modes. Some compounds form only tiny crystals, too small for conventional INS. We will develop a bespoke device for their precise co-alignment, which will have an immense impact on neutron scattering beyond the scope of the project.

Aims

The project aims to show, that ME effects are a general property of condensed matter and the Born-Oppenheimer approximation is surpassed far more often than generally thought. To reach this goal we will build a unique device allowing neutron measurements on samples too small to measure before.

Abstract

Close-in extrasolar systems of low-mass planets (super-Earths and mini-Neptunes) represent a substantial fraction of the exoplanet population discovered by recent astronomical observations. Our project aims to study hydrodynamic interactions between low-mass planets and their natal protoplanetary disk in order to constrain the processes which contributed to formation of closein exoplanets. First, we plan to analyze migration of low-mass planets towards the inner disk regions. We will explore the influence of gravitational torques induced by pebble accretion, gravity of a pebble disk, and pebble concentrations at pressure maxima. Second, we will focus on planet-disk interactions at the inner disk rim which is sculpted by stellar irradiation and viscosity transitions. Understanding the evolutionary phase at the inner disk rim represents a critical step in understanding the origin of close-in exoplanets. Our results will be obtained by means of 3D and 2D radiation hydrodynamic simulations and they will be confronted with existing theories of planet formation and observations

Aims

We will study interactions of planets and protoplanetary disks by means of numerical hydrodynamic simulations. The aim of the project is to improve the understanding of processes which led to the formation of close-in low-mass extrasolar planets.

Abstract

The concept of information is ubiquitous in current logic. However, the informational interpretation of various logical approaches is rather scattered in the logical literature and a unification is needed. The main goal of this project is to develop unifying philosophical foundation for the logical concept of information based on Barwise’s theory of information channels. Special attention will be paid to the application of this general approach to two more specific areas of logical inquiry: fuzzy logic of graded information and epistemic logic of knowledge and belief. For these two distinct fields of logic a common semantic basis will be provided that will make possible transfer of results from one area into the other.

Aims

We will develop unifying philosophical foundation for the logical concept of information based on Barwise’s theory of information channels, and apply this general approach to two more specific areas of logical inquiry: fuzzy logic of graded information and epistemic logic.

Abstract

Autoimmune regulator (Aire) plays an essential role in the induction of self-tolerant T cells during their development in the thymus by generating a mirror image of the body’s own peripheral antigen repertoire within the medullary thymic epithelial cells (mTECs). Subsequent presentation of these self-antigens by mTECs is essential for deletion of self-reactive T-cell clones and prevention of autoimmunity. Interestingly, most AIRE-mutation bearing patients suffer from candidiasis, which represents one of the most common and earliest manifestations of this mutation. Recently, we were able to show that Aire is expressed in a rare extrathymic population of MHCII positive type-3 innate lymphoid cells (ILC3) and that these Aire-ILC3 like cells regulate the Th17 response to C. albicans. This project is focused on delineating the mechanisms imposed by Aire-ILC3 like cells to regulate the Th17 response in response to extracellular pathogens or during autoimmune reaction. Together, the proposed research project should help our understanding of the Aire role in regulation of Th17 response.

Aims

This project is focused on delineating the molecular mechanisms imposed by Aire-ILC3 like cells to regulate the Th17 response. Moreover, we would like to explore the role of Aire-ILC3 like cells in regulation of Th17 response to extracellular pathogens or during Th17-dependend autoimmune reaction

Abstract

Fungi are eukaryotic microorganisms that play fundamental roles in regulating key ecosystem processes. As major decomposers of organic matter as well as mutualists or pathogens of plants, soil fungi significantly influence plant primary production, carbon sequestration, and act as crucial regulators of the soil carbon balance, which is one of the greatest topics of human security. Although the wealth of our civilization profoundly depends on globalization and free market, there is also another side to this coin, represented by the global changes of environment and easier spread of pathogens of humans, animals and plants. Climate change and world biota globalization constitute most important challenges which affect the functioning of natural as well as agricultural ecosystems. Understanding the consequences of inevitable global changes on biota and ecosystem functioning have to be primary interest of current biological research.

Aims

In this project I aim to determine the effects of climate change and biological invasions on worldwide distribution of fungal species. I also aim to determine how these changes in fungal species distribution, caused by climate change or biological invasions, will affect ecosystem processes.

Abstract

During the juvenile period the growth is determined by the nutrient intake and by production of growth hormones. Recently, we have identified intestinal bacteria as a key player in growth with specific Lactobacillus plantarum (Lp) strain being sufficient to reproduce the effect of the microbiota in monoassociated ex-germ-free mice. Our unpublished data show that Lp retains its growth promoting capacity after treatment of conventional mice and that this effect is Lp strain specific and independent of the Lp viability status. By using multilateral approach we will explore Lp- and Bifidobacteria-derived postbiotics and host receptors that are engaged in the molecular cross-talk resulting in the enhanced growth during chronic undernutrition. Further, we will characterize the impact of the protein undernutrition on the host immune system and its changes after treatment with selected postbiotics. Results of this project will shed light on the bacteria-host crosstalk during growth and pave way to amelioration of the long-term sequelae of undernutrition in children.

Aims

By using multilateral approach, this project aims at identification of lactobacillus- and bifidobacteria-derived postbiotics and host receptors that are engaged in the molecular crosstalk resulting in the enhanced host systemic growth during chronic undernutrition.

Abstract

Climate models predict substantial changes in temperature and precipitation patterns across the Arctic regions in future decades. Microbes are known to play key roles in determining the stability of soil carbon (C) and its possible release into the atmosphere as carbon dioxide and methane. Carbon-rich Arctic soil ecosystems are particularly vulnerable to C losses due to warming and subsequent ecosystem disturbances as wildfires. On the other hand, the release of C from soil to the atmosphere could be mitigated due to increased plant growth or reduced due to drought. Here we propose to characterize the response of soil microbes to the conditions caused by future climate change (increased winter precipitation, summer warming and wildfires); and to identify microbial processes affecting shrub expansion in Greenland. By combining soil, plant and microbial C pools and fluxes at the sites, the study will help in understanding whether Arctic soils will become C sink or source under future climate change.

Aims

The aim of the project is to comprehensively explore the response of soil microbial communities to the conditions caused by future climate change, specifically increased winter precipitation, summer warming and wildfire disturbance; and identify microbial drivers of shrub expansion in Arctic tundra.

Abstract

Phosphorus is a core, limiting macronutrient, but its global turnover is still little understood. For example, one quarter of all phosphorus in the ocean occurs as phosphonates, whose metabolism has only been thoroughly studied in bacteria. We identified unexpectedly widespread phosphonate enzymes in eukaryotic genomes and predict that they comprise a novel mitochondrial pathway. To test this, we will computationally map phosphonate enzyme distribution, expression, and cellular localization in all eukaryotes, then localize them subcellularly in two distantly related protists, Perkinsus and Capsaspora. We will next use labeled precursors to track phosphonate metabolism in both species, and measure the ability of a wide range of algae to utilize phosphonate substrates for growth. We will also reconstruct the evolutionary history of all phosphonate enzymes and how they relate to eukaryogenesis. Our findings will illuminate mitochondrial metabolism, eukaryotic evolution, and phosphorus turnover in cells and ecosystems, and identify new enzymes of potential commercial interest.

Aims

To illuminate the global phosphorus cycle, we will characterize the distribution, functionality, localization and evolution of phosphonate metabolism across the diversity of eukaryotes, a candidate novel and widespread mitochondrial pathway fundamental to phosphorus turnover in cells and ecosystems.

Abstract

The project aims to eliminate the gap between fundamental bounds and actual performance of inverse-designed devices in electromagnetism by revolutionizing approaches to design synthesis. A combination of local gradients of a performance metric over a fixed discretized model and the ability to avoid local minima are the main tools required to achieve this goal. Employing the exact reanalysis allows for unprecedented speed in evaluating full-wave models. A class of geometry- and topology-based operators is proposed to deal with regularity, conformity, and similarity of designs to act as constraints to remove highly irregular shapes, increase tolerance against manufacturing imperfections, and offer a full set of feasible designs. The proposed synthesis method is general and discoveries of structures with unique shapes and properties is expected from low to ultra-high frequencies. The project assumes intense collaboration with world-leading authorities and a multidisciplinary focus having the potential to open a new field of research.

Aims

O1: To formulate and solve the problem of shape synthesis using the exact reanalysis technique. O2: To develop geometry- and topology-based operators to regularize shapes. O3: To implement the theoretical findings of O1-O2 as a software package. O4: To experimentally verify O1-O3 on prototypes.

Abstract

This junior project aims on the design and manufacturing of a new class of interstitial Ti alloys and refractory metals high entropy alloys (HEAs) exhibiting the transformation induced plasticity (TRIP) effect. To achieve the TRIP effect in Ti alloys with increased content of interstitial oxygen (i.e. increased strength) and in HEAs, the composition must be carefully tuned with respect to the stability of bcc phase. Main applicant will employ his experiences with developing new Ti alloys and the fact that metallurgy of bcc HEAs is strikingly similar to the metallurgy of bcc Ti alloys. Manufactured materials will be thoroughly characterized by a wide variety of experimental techniques including scanning and transmission electron microscopy, x-ray, electron and neutron diffraction. These results will be correlated with mechanical properties determined by tensile tests complemented by digital image correlation. The effect of composition variations on the TRIP effect will be assessed to obtain the material with the best combination of strength and ductility.

Aims

The aim of the project is to design, to manufacture and to characterize interstitial Ti alloys, high entropy alloys (HEAs) and interstitial HEAs exhibiting the TRIP effect and consequently both the high strength and ductility.

Abstract

This project will develop a new method for spatial manipulation of light at the nanoscale by assembly of plasmonic nanostructures. I propose to use this method to advance visualization of densely packed biomolecules and their dynamics. Metal nanostructures are capable of massive enhancements of optical response, which arise from collective electromagnetic resonances called plasmons. Here, I propose a radically new idea of understanding plasmonic nanoparticles as nanoscale spatial manipulators for light emitting fluorophores, opening a new dimension of diverse applications. We will use single molecule localization microscopy, DNA self-assembly, and machine learning to describe and reconstruct sub-diffraction limited shifts in the projection of plasmon-coupled fluorophores and determine how to control them by altering the enhancement mechanism, fluorophore-plasmon distance, and their dynamics. The experimental systems developed in this project will bring new routes to answering fundamental questions in plasmonic enhancement well beyond the scope of this project.

Aims

To alternate the enhancement mechanism of plasmon-coupled fluorophore. To control the shift in the projected position of plasmon coupled fluorophore by enhancement mechanism. To determine the distance-dependence of the fluorophore projection. To construct dynamic plasmonic system.

Abstract

My research focuses on the regulation of protein trafficking at the cell surface by a highly dynamic process – endocytosis. This process determines the composition of the cellular plasma membrane and it is a major pathway for viral and pathogen entry, including Ebola and Coronovirus. The dysfunction of endocytosis is also a causal factor behind a number of human genetic diseases, and its dysregulation contributes to wide range of pathologies, including neuropathic pain. Despite its critical importance, surprisingly little is known about how it is regulated. A major regulation point is the dynamic phosphorylation of endocytic components by kinases. However, it is poorly understood which kinases (and phosphatases) control endocytosis even though they represent targets for disease-modifying therapies. My vision is to understand the regulatory role that protein kinases have in membrane-trafficking. My focus is on the Numb-Associated Kinase family (NAK) and their role in pain sensing.

Aims

“I seek to deliver a comprehensive, mechanistic model of the functioning of Numb-associated kinases (NAKs). Objective
1) Elucidating AAK1 and BMP2K related pathways,
2) Elucidating mechanisms of NAK regulation and
3) Determining the consequences of NAK deregulation for the plasma membrane proteome.”

Abstract

Alchemies of Scent investigates how the quest to extract, concentrate, compound and preserve the essences of plants influenced natural philosophy, medicine and culture in the ancient world. It focuses on the encounter of ancient Greek philosophy with the technologies of Egyptian perfumery from the time of Alexander the Great to Cleopatra VII (fourth–first centuries BCE). Using experimental replications of Greco-Egyptian recipes, it reconstructs the practices of this ancestor to modern chemistry and studies the ways these practices were understood. It will produce a lexicon of Egyptian, Greek, and Latin perfumery; a manual of recipes and procedures; three monographic studies on perfume making in the context of the history of science and culture; and it will encourage citizen science and education through exciting social media content

Aims

“1. Produce a lexicon of ancient Egyptian–Greek–Latin perfumery
2. Replicate ancient Greco-Egyptian perfume-making methods
3. Study perfumery in ancient Egyptian and Greek science, medicine, and literary and material culture
4. Encourage citizen science and education through public engagement”

Abstract

The overarching aim of this proposal is to understand molecular mechanisms underlying semaphorin-plexin signalling. Semaphorin ligands and their plexin receptors are one of the classical cell guidance factors that play essential roles in cell processes requiring discrete changes in the cytoskeleton. Although the field has made enormous advances in understanding semaphorin function at the level of genetic and cellular experiments, our knowledge of the molecular-level mechanisms of semaphorin signalling is still lacking. My laboratory will address three fundamental questions: (1) How do proteoglycans modulate the axon navigation towards their target? (2) How does OTK co-receptor control semaphorin-plexin signalling? (3) How does a signal from outside the cell pass to cytoplasmic plexin domain? To address these challenges, we will use a hybrid approach integrating X-ray crystallography with cryo-electron microscopy and tomography. This approach will be further combined with biophysical and cellular experiments in neurons and transgenic flies.

Aims

“1. Dissect molecular mechanisms of proteoglycan-based modulation of semaphorin function 2. Elucidate the interplay OTK co-receptor and semaphorin-plexin signalling
3. Explore the molecular mechanisms through which the extracellular and cytoplasmic segments of plexins communicate”

Abstract

Nitrifiers and methanotrophs are microbial guilds responsible for aerobic transformation of reactive nitrogen and oxidation of methane, respectively. Both processes are fundamental ecosystem functions linked to nutrient cycling and global change. We hypothesize that interactions between these two guilds substantially contribute to the modulation of process rates. However, such interactions have hardly been investigated. The proposed line of research will expose the cause and nature of interactions between nitrifiers and methanotrophs and quantify their ecological impact. The project will employ a unique combination of multidisciplinary techniques, i.e. next generation sequencing, stable isotope incubations with integrated approaches of metagenomics and metatranscriptomics, single cell sorting, and metaproteomics with synthetic microbial consortia. Collectively, these approaches are poised to gather a deep understanding of the links between carbon and nitrogen cycling to eventually be able to predict and mitigate climate change and protect Earths ecosystems.

Aims

The project will resolve interactions between nitrifiers and methane oxidizers, quantify their ecological implications, and develop models for predictions. It will fill knowledge gaps on microbial ecogenomics and -physiology, establish a new stable isotope probing method, and isolate new organisms.

Abstract

Public procurement accounts for 12% of GDP in developed countries. Hence, the efficiency of procurement markets is a first-order issue in modern economies. The proposed research project will focus on three key understudied aspects of public procurement that likely influence procurement outcomes (such as prices, quality, and delays) and economic efficiency of procurement markets: (i) single-bidding in procurement contracts, (ii) the availability of information about public procurement contracts to firms, and (iii) public online oversight and monitoring. The first and the third objective will be conducted on high-quality administrative datasets from the Czech Republic and Ukraine, respectively. The second objective will be addressed by a field experiment. We aim to contribute to the academic literature by identifying causes of inefficiencies in the procurement markets and quantifying their extent. Our findings and the policy recommendations derived from them should, if implemented, result in a more efficient public sector.

Aims

The main goal of the research project is to quantify the extent of inefficiencies on public procurement markets caused by three understudied institutional factors and suggest policies which would result in savings and/or a more efficient public sector if they were implemented.

Abstract

This is an interdisciplinary programme bridging cosmology, astrophysics and particle physics towards explaining dark energy in the Universe. The resolution of dark energy needs an extension of General Relativity. Theories aiming to explain it typically introduce new fields manifesting as a fifth force. The quest for their theoretical underpinning and observational imprints is currently paramount in cosmology. In the project’s first part, I will introduce helioseismology as a new precision probe for fifth forces in Nature. Within generic theories for dark energy, I will formulate the theory for solar pulsations, and with sophisticated simulations I will deliver the tightest constraints on the fifth force to date. In the second part, I will perform a complementary investigation of the fundamental character of general dark energy theories. With state-of-the-art field-theoretical methods I will deliver the first complete description of their quantum origin. With this, I will make robust predictions for gravitational waves for current and future surveys.

Aims

“Within generic dark energy theories:
1: Modelling of solar evolution in presence of the fifth force
2: Modelling of solar eigenspectrum and tight constraints on fifth force
3: Resolve their perturbative quantum structure and its phenomenology
4: Address their Wilsonian UV completion”

Abstract

Triatominae are important blood feeding disease vectors. The project focuses on structure and development of their microbiomes, including interactions with transmitted pathogens. Recently, we identified several novel aspects of triatomine-bacteria associations, which point out unique potential of these vectors for entirely new insights into the principles of insect-bacteria symbiosis. We have proved that i) the microbiomes undergo ontogenetic diversity shift, ii) the dominant microbiome taxa enter intracellular symbiosis, and iii) the microbiomes of wild Triatoma populations encounter a complex pathobiome. The project builds on these novel findings and proposes to investigate microbiome development and bacteria transmission mechanism, functional analogies between the intracellular assemblies and bacteriomes of other hematophagous vectors, pangenomes of microbial communities found within US native Triatoma populations, and specific microbiome changes in respect to an underestimated complexity of the pathobiome, including T. cruzi DTUs, other eukaryotic, bacterial and viral pathogens.

Aims

“To reveal
i) specific changes of Triatoma microbiomes in respect to the complex pathobiome,
ii) characteristics of intracellular symbiosis found in R. prolixus and its functional analogies to tsetse bacteriomes,
iii) pangenome capacities of microbiota associated with wild Triatoma populations.”

Abstract

We propose to develop analytical tools to support the investigation of the locomotion of softbodied animals and robots. Our study will be focused on limbless locomotion, adopted in Nature by earthworms, snakes and snails, and inspiring a new generation of bio-mimetic soft robots, with applications in medical intervention and survey of complex environments. Instead of singularly studying specific models, we propose to build up general results in an abstract framework, where all the various mechanisms employed by such locomotors can be included. We study properties such as stabilization and optimality, and propose to rigorously derive some features of the models using multiscale convergence results. The main mathematical challenges in the analysis of such systems are the soft body, implying that its actual shape is not directly controlled, the presence of non-smooth friction laws, such as dry friction, and the absence of Dirichlet boundary conditions. Our approach combines techniques from nonsmooth analysis, dynamical systems, calculus of variation and optimal control.

Aims

– Development of analytical tools from nonsmooth analysis for the study of stabilitation and optimality in soft locomotors – Rigorous derivation of some properties of the locomotors using multiscale convergence methods.

Abstract

Searching for quantum effects in biology is a grand topic of biophysics. On one hand, there are suggestions for quantum effects on such a macroscopic scale as a human brain; on the other hand, there are heated disputes over tiny localized intramolecular processes in proteins. There are experimental implications that certain quantum effects such as charge or exciton delocalization can indeed be purposely enhanced by the protein environment. Those are e.g. unusually long-lasting coherences observed by 2D spectroscopy in light-harvesting antennas of plants. Unfortunately, it has turned out that it is difficult to assess if the observed oscillations are genuine quantum effects. For assessing how “quantum” the nature of any molecular process is, we are missing “Occam’s razor” techniques. Here I propose that utilizing the deep connection between quantum decoherence and the entanglement collapse might provide such a tool. Generating and analyzing entangled bi-photons generated from chromophores in proteins (such as OCP) should provide direct insight into quantum effects in Biosystems.

Aims

The goal is to reliably set decoherence times of cofactors in proteins by generation of entangled photons in them. These times would be compared with decoherence times determined from free cofactors. This information should shed light on hypotheses about long living coherences in certain biosystems

Abstract

The interplay between DNA repair and transcription is a complex and poorly understood. On one hand, transcription is one of the mayor sources of DNA damage. On the other hand, under particular circumstances, cells use transcription machinery to efficiently initiate DNA repair. As the in vivo methods are inherently unable to uncover the causal relationships between DNA repair and transcription, we decided to study the above-mentioned processes by a combination of biochemical and structural approaches. The aim of the project is to determine the 3D structures of RNAPII with key factors promoting the cross-talk between transcription and DNA repair (BRCA1, SENATAXIN), coupled with a thorough biochemical analysis of the complexes. The combination of these approaches will provide a complex and detailed characterisation of the interplay between DNA repair and transcription.

Aims

“Our overall aim is to is to determine the molecular mechanism of the cross-talk between DNA repair and transcription. In particular:
(i) to solve the 3D structure of the complex between mammalian RNAPII with key DNA repair factors;
(ii) to biochemically characterise the abovementioned complexes.”

Abstract

We hypothesise that multinational corporations (MNCs) avoid paying corporate income taxes by exploiting a combination of globalisation and countries’ sovereignty to set tax policies. Consistent with this hypothesis, we propose a new framework: the inescapable trilemma of corporate taxation. We argue that only two of three policy goals in this trilemma – globalisation, sovereignty, and revenue – can be achieved at any given time. We hypothesise that, at present, revenue is not being achieved. We aim to test it by determining the extent to which the existing limited evidence of MNCs’ tax avoidance represents a general pattern. Unlike previous research, we will overcome the limitations of currently available data. We propose a new empirical methodology and use two breakthrough ideas to establish how much MNCs pay in taxes, where and why. First, we will pioneer the use of country-by-country reporting data from large MNCs. Second, we will combine that data with other sources and leverage their respective strengths to create the most comprehensive data set on MNCs.

Aims

We aim to establish how much MNCs pay in taxes, to what extent these taxes are paid in tax havens, and which factors drive these patterns. Ultimately, we will use our theoretical, methodological and empirical innovations to transform the understanding of corporate taxation in the globalised world.

Abstract

We will focus on the elementary question of ecology: Are niches of tropical species narrower than species in higher latitudes? The answer, although fundamental for understanding the global biodiversity organisation, lacks for pollination interactions, the key driver of most terrestrial ecosystems. We propose an intensive inter-continental study of latitudinal specialisation patterns by standardised sampling of interactions at a whole-community level along a large latitudinal gradient from tropical to subarctic biomes. Interactions will be recorded by our unique video-recording of floral visitors and modern NGS metabarcoding of pollen from pollinators. We will dissect the patterns for entire communities, and for particular groups of plants and pollinators, together with detailed analyses of plant traits related to their reproduction strategies. We hypothesise no simple answer, therefore such complex approach is necessary. The expected differences among groups of pollinators and plants be used for macroecological and macroevolutionary analyses of the global biodiversity patterns.

Aims

“1/ We will sample pollination interactions at 7 sites along latitude.
2/ We will combine ‚traditional‘ observation and experimental approaches with ‚modern‘ NGS metabarcoding.
3/ We will reveal latitudinal specialisation patterns of communities, as well as particular groups of plants and pollinators”

Abstract

Above 1 PeV, the properties of cosmic rays can only be inferred indirectly through the detection of extensive air showers. The interpretation of air shower observables at 10 EeV relies on extrapolations of accelerator data by about one order of magnitude in energy, where a proper description of the very forward physics, most relevant for the shower development, is lacking. This leads to unknown systematic uncertainties in the predictions of hadronic interaction models and inconsistencies in the description of air shower data. We aim at improving the current situation through a comprehensive study of the main shower observables (lateral and longitudinal profiles of muon and electromagnetic components) and of the properties of current hadronic interaction models using data of several air shower experiments. The analysis will be based on several popular simulation codes and will include an unprecedented wide scan on the hadronic parameters (cross-section, multiplicity, elasticity, pion-charge ratio) placing constraints on the hadronic interaction models and exotic physics scenarios.

Aims

Reduction of the uncertainties of current simulation codes towards an improved description of various shower observables via analysis of public data from several air shower experiments. Adjustment of the interactions model parameters causing inconsistencies in the interpretation of data.

Abstract

We will establish a new connection between the multiplicative and additive structures of number fields. This will have important implications, e.g., for 1. universal quadratic forms over (totally real) number fields, estimating their ranks and proving 290-theorems, and 2. class numbers of number fields, determining their precise asymptotic growth in a wide class of families and discovering new techniques for dealing with the class number one problem. We aim at proving the following fundamental hypothesis: For a given number field K, the larger the class number of K is, the fewer indecomposable algebraic integers in K there are, and the smaller the ranks of universal quadratic forms over K are. Methodology is based on a combination of geometric (quadratic lattices), analytic (modular forms, L-functions), and arithmetic (indecomposables, generalized continued fractions) techniques. Despite promising preliminary results over real quadratic fields, further progress will require substantial effort to achieve much needed breakthroughs, starting with the case of cubic fields.

Aims

“Our main goals are to:
1. describe indecomposables using generalized continued fractions;
2. characterize corresponding families of number fields;
3. apply the results to universal quadratic forms;
4. refine the theory of infrastructure in number fields to obtain new connection with class numbers.”

Abstract

Bioactive specialized metabolites from plants represent an essential source of chemical scaffolds for the development of new medicines, but new technological platforms are urgently needed to fully utilize this natural resource. In this project we will expand the capabilities of the popular MZmine platform for metabolomics into the domains of ion mobility separation and molecular networking, two state-of-the-art techniques that are essential for effective isolation and identification of diverse plant natural products. We will further develop and evaluate a novel bioinformatic approach based on genetic networking to associate plant natural products with their biosynthetic enzymes. We will demonstrate these technological advancements by mapping the chemodiversity of the Piperaceae plant family, widely recognized as a remarkable and underexplored reservoir of bioactive specialized metabolites.

Aims

“1. Expand the MZmine platform with ion mobility separation and molecular networking modules.
2. Develop a genetic networking approach to associate plant metabolites with their biosynthetic enzymes.
3. Map the chemodiversity and specialized biosynthetic networks of the Piperaceae plant family.”

SOUVISEJÍCÍ ČLÁNKY